A new technology for genome editing may put the zinc finger nuclease franchise out of business, some believe. Not so fast, say the finger people. Laura DeFrancesco reports.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
TALEN mediated targeted editing of GM2/GD2-synthase gene modulates anchorage independent growth by reducing anoikis resistance in mouse tumor cells
Scientific Reports Open Access 12 March 2015
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Change history
09 January 2012
In the version of the article originally published, Figure 1 incorrectly cites Romer et al, Plant Physiol., 2009 as the article that demonstrates “Promoter customized to bind 3 TAL effectors.” It should have cited Romer et al., Proc. Nat. Acad. Sci. USA (2009). The errors have been corrected in the HMTL and PDF versions of the article.
References
Scott, C.T. Nat. Biotechnol. 23, 915–918 (2005).
Romer, P. et al. Science 318, 645–648 (2007).
Boch, J. et al. Science 326, 1509–1512 (2009).
Moscou, M.J. & Bogdanove, A. Science 326, 1501 (2009).
Christian, M. et al. Genetics 186, 757–761 (2010).
Morbitzer, R. et al. Proc. Natl. Acad. Sci. USA 107, 21617–21622 (2010).
Cermak, T. et al., Nucl. Acids Res. 39, e82 (2011).
Li, T. et al. Nucl. Acids Res. published online, doi:10.1093/nar/gkr188 (31 March 2011).
Miller, J.C. et al. Nat. Biotechnol. 25, 778–785 (2007).
Miller, J.C. et al. Nat. Biotechnol. 29, 143–148 (2011).
Hurt, J.A. et al. Proc. Natl. Acad. Sci. USA 100, 12271–12276 (2003).
Sander, J.D. et al. Nat. Methods 8, 67–69 (2011).
Zhang, F. et al. Nat. Biotechnol. 29, 149–153 (2011).
Rights and permissions
About this article
Cite this article
Move over ZFNs. Nat Biotechnol 29, 681–684 (2011). https://doi.org/10.1038/nbt.1935
Published:
Issue Date:
DOI: https://doi.org/10.1038/nbt.1935
This article is cited by
-
Tobacco as green bioreactor for therapeutic protein production: latest breakthroughs and optimization strategies
Plant Growth Regulation (2023)
-
TALEN mediated targeted editing of GM2/GD2-synthase gene modulates anchorage independent growth by reducing anoikis resistance in mouse tumor cells
Scientific Reports (2015)