To date, large-scale 'omics data sets and systems approaches in biology have had a relatively minor impact on the practice of medicine. As new technology brings individual genome sequencing closer to reality and large-scale biology continues to progress, opportunities are likely to open up in disease prediction, prevention, diagnosis and treatment. Here the views of two researchers on the potential of disruptive biomedical technologies in clinical practice are contrasted with the perspectives of a clinician and an entrepreneur in commercial clinical information technology.

POINT: Are we prepared for the future doctor visit?

COUNTERPOINT: Do not opine before it's time