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Megabases for kilodollars

Two approaches for selecting oligonucleotides from complex mixtures improve the fidelity and scalability of DNA synthesis.

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Figure 1: Assembly of user-defined DNA sequences from low-cost raw materials.

Katie Vicari

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Correspondence to Mikkel Algire or Chuck Merryman.

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Algire, M., Krishnakumar, R. & Merryman, C. Megabases for kilodollars. Nat Biotechnol 28, 1272–1273 (2010). https://doi.org/10.1038/nbt.1723

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