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Nature Biotechnology 27, 620 - 621 (2009)
doi:10.1038/nbt0709-620
Minicells overcome tumor drug-resistance
Emmanouil D Karagiannis1 & Daniel G Anderson1
- Emmanouil D. Karagiannis and Daniel G. Anderson are at the David H. Koch Institute for Integrated Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Correspondence to: Daniel G Anderson1 e-mail: dgander@mit.edu
Abstract
Bacterially derived minicells loaded with siRNA reverse drug resistance in tumor xenografts.
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RESEARCH
Sequential treatment of drug-resistant tumors with targeted minicells containing siRNA or a cytotoxic drugNature Biotechnology Research (01 Jul 2009)


