J. Craig Venter reflects on an effort spanning decades to create a living cell from chemically synthesized building blocks.
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References
Lartigue, C. et al. Creating bacterial strains from genomes that have been cloned and engineered in yeast. Science 325, 1693–1696 (2009).
Hutchison, C.A. III et al. Global transposon mutagenesis and a minimal mycoplasma genome. Science 286, 2165–2169 (1999).
Smith, H.O., Hutchison, C.A. III, Pfannkoch, C. & Venter, J.C. Generating a synthetic genome by whole genome assembly: ΦX174 bacteriophage from synthetic oligonucleotides. Proc. Natl. Acad. Sci. USA 100, 15440–15445 (2003).
Gibson, D.G. et al. Complete chemical synthesis, assembly and cloning of a Mycoplasma genitalium genome. Science 319, 1215–1220 (2008).
Lartigue, C. et al. Genome transplantation in bacteria: changing one species into another. Science 317, 632–638 (2007).
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Marshall, A. The sorcerer of synthetic genomes. Nat Biotechnol 27, 1121–1124 (2009). https://doi.org/10.1038/nbt1209-1121
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DOI: https://doi.org/10.1038/nbt1209-1121