Table 2
From the following article
Brazilian health biotech—fostering crosstalk between public and private sectors
Rahim Rezaie, Sarah E Frew, Stephen M Sammut, Maya R Maliakkal, Abdallah S Daar & Peter A Singer
Nature Biotechnology 26, 627 - 644 (2008)
doi:10.1038/nbt0608-627
Table 2. Financial background for companies intervieweda
| Company name | Year founded | Public or private | Approximate revenues (millions Brazilian reais (R$) or US dollars ($)) | Grants or low-interest loans from governmental sources (millions Brazilian reais (R$) or US dollars ($)) | Sources of private investment/amounts (millions Brazilian reais (R$) or US dollars ($)) | Revenues from exports (millions Brazilian reais (R$) or US dollars ($)) | Approximate R&D expenditure annually or as statedb (millions Brazilian reais (R$) or US dollars ($)) | Total number of employees (involved in R&D where available) |
|---|---|---|---|---|---|---|---|---|
aSome figures were provided to us in US dollars, others in Brazilian reais (R$). For consistency, data are presented in both currencies using an exchange rate of $1 being equal to | ||||||||
bR&D expenditure is not limited to activities related to novel product development; four digit numbers in parentheses. | ||||||||
cBiolab and União Química Farmacêutica Nacional are both owned by Castro Marques Group. | ||||||||
dCryopraxis Criobiologia is a spin-off of Silvestre Laboratories and has now established its own subsidiary in the United States called CellPraxis USA Inc. (Jupiter, FL, USA). | ||||||||
eRSTec Venture Fund is a joint creation of Inter-American Development Bank, Brazilian Development Bank (BNDES) and other individuals and programs. | ||||||||
fSince the interview, Katal Biotecnológica has been taken over by Interteck International Imp. e Exp. (São Paulo), a former shareholder, and its founder Leonides Rezende has started a new firm focused on molecular diagnostics. N/A, data not available or not disclosed; FINEP, Financiadora de Estudos e Projetos–Brazilian National Studies and Project Funding Agency; FACEP, Fundação de Amparo à Ciência e Tecnologia do Estado de Pernambuco–State of Pernambuco Science and Technology Funding Agency; CNPq, Conselho Nacional de Desenvolvimento Científico e Tecnológico–National Counsel of Scientific and Technological Development; BNDES, Banco Nacional de Desenvolvimento Econômico e Social–Brazilian Development Bank; RHAE, Recursos Humanos Em Áreas Estratégicas–Human Resources in Strategic Areas; FAPESP, Fundação de Amparo à Pesquisa do Estado de São Paulo–The São Paulo State Funding Agency. | ||||||||
| Aché Laboratórios Farmacêuticos | 1966 | Private | R$1.77 ($951) | N/A | N/A | R$1.1 ($0.54) in 2006 | R$11.9 ($6.4) | 2,800 |
| BIOCANCER | 2004 | Private | N/A | R$1.5 ($0.8) in 2005 and 2006 | Investors include FIR Capital, Biominas Foundation, Jardim Botânico Partners' Novarum Fund (all based in Belo Horizonte)/amounts not disclosed | Many foreign clientele | N/A | 15 |
| Biogene | 1995 | Private | R$0.17 ($0.094) | R$0.09 ($0.05) each year from FINEP and FACEPE | N/A | Just started exporting | R$0.098 ($0.053) | 4 (4) |
| Biolab Sanus Farmacêutica | 1996 | Privatec | R$335 ($180) | R$3.7 ($2) from FINEP; R$0.93 ($0.5) from CNPq and R$37 ($20) from BNDES at 6% per year interest (R&D funds shared with União Química) | Castro-Marques Group/R$56 ($30) in past 3 years | N/A | R$20.8 ($11.2); approximately half targeted for radical innovation | 1,542 (35) |
| BIOMM | 2002 | Publicly listed (On BOVESPA) | R$5.6 ($3) | N/A | N/A | 100% foreign clientele base | N/A | 15 (8) |
| COINFAR | 2001 | Private | No revenues yet | R$3.8 ($2) from FINEP (2005–2007) | Founding shareholders R$11 ($6) from 2002 to 2006 | N/A | R$3 ($1.6) expected for 2008 to 2009 | 6 internal with 20 researchers contracted in Brazilian universities |
| Cryopraxis Criobiologia | 2001 | Privated | R$22.3 ($12) in 2007 | None | None | N/A | N/A | 100 (10) |
| Eurofarma Laboratórios | 1972 | Private | R$826 ($444) | FINEP funded projects with Brazilian universities (amounts not disclosed) | N/A | N/A | R$37 ($20) | 2,300 (20) |
| FK Biotecnologia | 1999 | Private | R$0.37 ($0.2) in 2006; R$1.86 ($1) up to July 2007 | FINEP loan of R$0.14 ($0.075) in 2001. FINEP grants totaled R$ 3.7 ($2) from 2005 to 2007. R$0.07 ($0.04) in 2004 | Angel investors provided R$0.034 ($0.02) in 1999. First-round VC by RSTec venture funde R$1.16 ($0.62) in 2000 | Small amounts | R$1.86 ($1) | 25 (18) |
| Hebron Farmacêutica | 1990 | Private | R$56 ($30) | N/A | N/A | N/A | N/A | 550 |
| Intrials Latin America Clinical Research | 1999 | Private | N/A | N/A | 3 angel investors | Most foreign clientele | N/A | 30 |
| Katal Biotecnológica | 1994 | Private | R$4.6 ($2.5) in 2005 | N/A | Investment by Interteck Internacional Imp. e Exp. (São Paulo) f amount not disclosed | N/A | N/A | 35 (2) |
| Labtest Diagnóstica | 1971 | Private | R$31.6 ($17) in 2006 estimated at R$35 ($19) in 2007 | Low-interest loans from Bank of Development, Minas Gerais R$2.8 ($1.5) and BNDES R$2.4 ($1.3) | Undisclosed private sources provided R$0.9 ($0.49) | R$0.84 ($0.45) | R$1.15 ($0.62) | 110 (27) |
| Nortec Química | 1985 | Private (partly owned by government) | R$37 ($20) in 2006 | R$6 ($3.2) from FINEP | N/A | 10% of sales revenues | N/A | 180 (6) |
| Pele Nova Biotecnologia | 2003 | Private | R$1.86 ($1) in 2006; estimated at R$3.3 ($1.8) in 2007 | None | REIF Fund (managed by DGF Investments in São Paulo) and two angel investors/over R$7.4 ($4) | N/A | 35% of revenues and investments | 15 (4) |
| Recepta Biopharma | 2006 | Private | No revenues yet | R$16 ($8.6) from FINEP | Angel investors provided R$3.7 ($2) | N/A | R$6.1 ($3.3) | 4 (43 in partner institutions) |
| Scylla Bioinformatics | 2002 | Private | N/A | R$0.15 ($0.08) from each of FINEP and FAPESP, with some funds from CNPq | Votorantim Venture (São Paulo) provided R$0.5 ($0.27) | N/A | N/A | 8 |
| Silvestre Laboratories | 1984 | Privated | R$18.6 ($10) | None | None | N/A | R$3.7 ($2) | 65 (10) |
| União Química Farmacêutica Nacional | 1936 | Private | R$279 ($150) in 2006 | See Biolab information above | See Biolab information above | N/A | R$3.7 ($2) year (for incremental innovation) and R$10 ($5.4) per year for radical innovation | 1,800 (some R&D shared with Biolab) |

R1.86 Brazilian reais (the approximate exchange rate on September 25, 2007). Where figures have been converted from US funds, the actual amounts in terms of Brazilian currency may differ slightly from the amount stated here depending on the actual exchange rate at the time when they were realized. All financial figures are close approximates and do not represent exact figures.