Table 2


From the following article

Brazilian health biotech—fostering crosstalk between public and private sectors

Rahim Rezaie, Sarah E Frew, Stephen M Sammut, Maya R Maliakkal, Abdallah S Daar & Peter A Singer

Nature Biotechnology 26, 627 - 644 (2008)

doi:10.1038/nbt0608-627

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Table 2. Financial background for companies intervieweda

Company nameYear foundedPublic or privateApproximate revenues (millions Brazilian reais (R$) or US dollars ($))Grants or low-interest loans from governmental sources (millions Brazilian reais (R$) or US dollars ($))Sources of private investment/amounts (millions Brazilian reais (R$) or US dollars ($))Revenues from exports (millions Brazilian reais (R$) or US dollars ($))Approximate R&D expenditure annually or as statedb (millions Brazilian reais (R$) or US dollars ($))Total number of employees (involved in R&D where available)

aSome figures were provided to us in US dollars, others in Brazilian reais (R$). For consistency, data are presented in both currencies using an exchange rate of $1 being equal to approxR1.86 Brazilian reais (the approximate exchange rate on September 25, 2007). Where figures have been converted from US funds, the actual amounts in terms of Brazilian currency may differ slightly from the amount stated here depending on the actual exchange rate at the time when they were realized. All financial figures are close approximates and do not represent exact figures.

bR&D expenditure is not limited to activities related to novel product development; four digit numbers in parentheses.

cBiolab and União Química Farmacêutica Nacional are both owned by Castro Marques Group.

dCryopraxis Criobiologia is a spin-off of Silvestre Laboratories and has now established its own subsidiary in the United States called CellPraxis USA Inc. (Jupiter, FL, USA).

eRSTec Venture Fund is a joint creation of Inter-American Development Bank, Brazilian Development Bank (BNDES) and other individuals and programs.

fSince the interview, Katal Biotecnológica has been taken over by Interteck International Imp. e Exp. (São Paulo), a former shareholder, and its founder Leonides Rezende has started a new firm focused on molecular diagnostics. N/A, data not available or not disclosed; FINEP, Financiadora de Estudos e Projetos–Brazilian National Studies and Project Funding Agency; FACEP, Fundação de Amparo à Ciência e Tecnologia do Estado de Pernambuco–State of Pernambuco Science and Technology Funding Agency; CNPq, Conselho Nacional de Desenvolvimento Científico e Tecnológico–National Counsel of Scientific and Technological Development; BNDES, Banco Nacional de Desenvolvimento Econômico e Social–Brazilian Development Bank; RHAE, Recursos Humanos Em Áreas Estratégicas–Human Resources in Strategic Areas; FAPESP, Fundação de Amparo à Pesquisa do Estado de São Paulo–The São Paulo State Funding Agency.

Aché Laboratórios Farmacêuticos1966PrivateR$1.77 ($951)N/AN/AR$1.1 ($0.54) in 2006R$11.9 ($6.4)2,800
BIOCANCER2004PrivateN/AapproxR$1.5 ($0.8) in 2005 and 2006Investors include FIR Capital, Biominas Foundation, Jardim Botânico Partners' Novarum Fund (all based in Belo Horizonte)/amounts not disclosedMany foreign clienteleN/A15
Biogene1995PrivateR$0.17 ($0.094)R$0.09 ($0.05) each year from FINEP and FACEPEN/AJust started exportingR$0.098 ($0.053)4 (4)
Biolab Sanus Farmacêutica1996PrivatecR$335 ($180)R$3.7 ($2) from FINEP; R$0.93 ($0.5) from CNPq and R$37 ($20) from BNDES at 6% per year interest (R&D funds shared with União Química)Castro-Marques Group/R$56 ($30) in past 3 yearsN/AR$20.8 ($11.2); approximately half targeted for radical innovation1,542 (35)
BIOMM2002Publicly listed (On BOVESPA)R$5.6 ($3)N/AN/A100% foreign clientele baseN/A15 (8)
COINFAR2001PrivateNo revenues yetR$3.8 ($2) from FINEP (2005–2007)Founding shareholders R$11 ($6) from 2002 to 2006N/AR$3 ($1.6) expected for 2008 to 20096 internal with 20 researchers contracted in Brazilian universities
Cryopraxis Criobiologia2001PrivatedR$22.3 ($12) in 2007NoneNoneN/AN/A100 (10)
Eurofarma Laboratórios1972PrivateR$826 ($444)FINEP funded projects with Brazilian universities (amounts not disclosed)N/AN/AR$37 ($20)2,300 (20)
FK Biotecnologia1999PrivateR$0.37 ($0.2) in 2006; R$1.86 ($1) up to July 2007FINEP loan of R$0.14 ($0.075) in 2001. FINEP grants totaled R$ 3.7 ($2) from 2005 to 2007. R$0.07 ($0.04) in 2004Angel investors provided R$0.034 ($0.02) in 1999. First-round VC by RSTec venture funde R$1.16 ($0.62) in 2000Small amountsR$1.86 ($1)25 (18)
Hebron Farmacêutica1990PrivateR$56 ($30)N/AN/AN/AN/A550
Intrials Latin America Clinical Research1999PrivateN/AN/A3 angel investorsMost foreign clienteleN/A30
Katal Biotecnológica1994PrivateR$4.6 ($2.5) in 2005N/AInvestment by Interteck Internacional Imp. e Exp. (São Paulo) f amount not disclosedN/AN/A35 (2)
Labtest Diagnóstica1971PrivateR$31.6 ($17) in 2006 estimated at R$35 ($19) in 2007Low-interest loans from Bank of Development, Minas Gerais R$2.8 ($1.5) and BNDES R$2.4 ($1.3)Undisclosed private sources provided R$0.9 ($0.49)R$0.84 ($0.45)R$1.15 ($0.62)110 (27)
Nortec Química1985Private (partly owned by government)R$37 ($20) in 2006R$6 ($3.2) from FINEPN/A10% of sales revenuesN/A180 (6)
Pele Nova Biotecnologia2003PrivateR$1.86 ($1) in 2006; estimated at R$3.3 ($1.8) in 2007NoneREIF Fund (managed by DGF Investments in São Paulo) and two angel investors/over R$7.4 ($4)N/Aapprox35% of revenues and investments15 (4)
Recepta Biopharma2006PrivateNo revenues yetR$16 ($8.6) from FINEPAngel investors provided R$3.7 ($2)N/AR$6.1 ($3.3)4 (43 in partner institutions)
Scylla Bioinformatics2002PrivateN/AR$0.15 ($0.08) from each of FINEP and FAPESP, with some funds from CNPqVotorantim Venture (São Paulo) provided R$0.5 ($0.27)N/AN/A8
Silvestre Laboratories1984PrivatedapproxR$18.6 ($10)NoneNoneN/AR$3.7 ($2)65 (10)
União Química Farmacêutica Nacional1936PrivateR$279 ($150) in 2006See Biolab information aboveSee Biolab information aboveN/AR$3.7 ($2) year (for incremental innovation) and R$10 ($5.4) per year for radical innovation1,800 (some R&D shared with Biolab)
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