1. Scott L. Diamond and Doron Greenbaum are in the Departments of Chemical Engineering and Bioengineering, University of Pennsylvania, 1024 Vagelos Research Laboratories, Philadelphia, Pennsylvania 19104-6383, USA. e-mail: sld@seas.upenn.edu

Abstract

Mass spectrometry analysis of proteome-derived peptide libraries enables high-throughput determination of protease substrate specificity.

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