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Opinion and Comment

Nature Biotechnology 26, 381–382 (1 April 2008) | doi:10.1038/nbt0408-381

Response to Transendothelial movement and caveolae

Phil Oh, Per Borgstr|[ouml]|m, Anne Simonson & Jan Schnitzer respond: Our paper describes the use of intravital microscopy to visualize, in real time and within a living animal, caveolae actively pumping a fluorescently labeled probe across the lung endothelium against a concentration gradient. The observations and methods of Heltianu et al. were very different from ours.