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Opinion and Comment

Nature Biotechnology 26, 271–272 (1 March 2008) | doi:10.1038/nbt0308-271

iPS cells and the politics of promise

Herbert Gottweis & Stephen Minger

To the editor: The paper published online in November by Yamanaka at Kyoto University (Kyoto, Japan) on the generation of induced human pluripotent stem (iPS) cells in the absence of c-Myc followed closely on the heels of a report published in Cell by the same group and another in Science from Thomson's group in Wisconsin. In late December, a third stem cell group from Harvard (Cambridge, MA, USA) also successfully generated iPS cells from a range of adult human somatic cells using protocols very similar to those of the Japanese group.