Table of contents


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News

Scientists cry foul as Europe plays politics with GM crops pp139 - 140

John Hodgson

doi:10.1038/nbt0208-139


China steps up US biotech intellectual property land grab pp141 - 142

Mark Ratner

doi:10.1038/nbt0208-141


Small molecule challenges dominance of TNF-alpha inhibitors pp143 - 144

Cormac Sheridan

doi:10.1038/nbt0208-143


Regulators weigh risks of consumer genetic tests pp145 - 146

Charles Schmidt

doi:10.1038/nbt0208-145


In Brief

News in brief pp147 - 148

doi:10.1038/nbt0208-147


Profile

Sidney Wolfe p149

Randall Osborne

doi:10.1038/nbt0208-149


Data Page

2007—a banner year for biotech p150

Stacy Lawrence

doi:10.1038/nbt0208-150


News Feature

Priced out of the UK market pp151 - 154

Nuala Moran

doi:10.1038/nbt0208-151


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Bioentrepreneur

Other ways of financing your company pp155 - 157

Jörn Aldag, Mark Kessel, Adrian Ibrahim, Ray Hill & Paul McCubbin

doi:10.1038/bioe.2008.1


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Opinion and Comment

Correspondence

FDA on transgenic animals—a dog's breakfast? pp159 - 160

Henry I Miller

doi:10.1038/nbt0208-159


Action needed to harmonize regulation of low-level presence of biotech traits pp161 - 162

Roger Krueger & Bernard Le Buanec

doi:10.1038/nbt0208-161


Metabolite identification via the Madison Metabolomics Consortium Database pp162 - 164

Qiu Cui, Ian A Lewis, Adrian D Hegeman, Mark E Anderson, Jing Li, Christopher F Schulte, William M Westler, Hamid R Eghbalnia, Michael R Sussman & John L Markley

doi:10.1038/nbt0208-162


Human Proteinpedia enables sharing of human protein data pp164 - 167

Suresh Mathivanan, Mukhtar Ahmed, Natalie G Ahn, Hainard Alexandre, Ramars Amanchy, Philip C Andrews, Joel S Bader, Brian M Balgley, Marcus Bantscheff, Keiryn L Bennett, Erik Björling, Blagoy Blagoev, Ron Bose, Samir K Brahmachari, Alma S Burlingame, Xosé R Bustelo, Gerard Cagney, Greg T Cantin, Helene L Cardasis, Julio E Celis, Raghothama Chaerkady, Feixia Chu, Philip A Cole, Catherine E Costello, Robert J Cotter, David Crockett, James P DeLany, Angelo M De Marzo, Leroi V DeSouza, Eric W Deutsch, Eric Dransfield, Gerard Drewes, Arnaud Droit, Michael J Dunn, Kojo Elenitoba-Johnson, Rob M Ewing, Jennifer Van Eyk, Vitor Faca, Jayson Falkner, Xiangming Fang, Catherine Fenselau, Daniel Figeys, Pierre Gagné, Cecilia Gelfi, Kris Gevaert, Jeffrey M Gimble, Florian Gnad, Renu Goel, Pavel Gromov, Samir M Hanash, William S Hancock, HC Harsha, Gerald Hart, Faith Hays, Fuchu He, Prashantha Hebbar, Kenny Helsens, Heiko Hermeking, Winston Hide, Karin Hjernø, Denis F Hochstrasser, Oliver Hofmann, David M Horn, Ralph H Hruban, Nieves Ibarrola, Peter James, Ole N Jensen, Pia Hønnerup Jensen, Peter Jung, Kumaran Kandasamy, Indu Kheterpal, Reiko F Kikuno, Ulrike Korf, Roman Körner, Bernhard Kuster, Min-Seok Kwon, Hyoung-Joo Lee, Young-Jin Lee, Michael Lefevre, Minna Lehvaslaiho, Pierre Lescuyer, Fredrik Levander, Megan S Lim, Christian Löbke, Joseph A Loo, Matthias Mann, Lennart Martens, Juan Martinez-Heredia, Mark McComb, James McRedmond, Alexander Mehrle, Rajasree Menon, Christine A Miller, Harald Mischak, S Sujatha Mohan, Riaz Mohmood, Henrik Molina, Michael F Moran, James D Morgan, Robert Moritz, Martine Morzel, David C Muddiman, Anuradha Nalli, J Daniel Navarro, Thomas A Neubert, Osamu Ohara, Rafael Oliva, Gilbert S Omenn, Masaaki Oyama, Young-Ki Paik, Kyla Pennington, Rainer Pepperkok, Balamurugan Periaswamy, Emanuel F Petricoin, Guy G Poirier, T S Keshava Prasad, Samuel O Purvine, B Abdul Rahiman, Prasanna Ramachandran, Y L Ramachandra, Robert H Rice, Jens Rick, Ragna H Ronnholm, Johanna Salonen, Jean-Charles Sanchez, Thierry Sayd, Beerelli Seshi, Kripa Shankari, Shi Jun Sheng, Vivekananda Shetty, K Shivakumar, Richard J Simpson, Ravi Sirdeshmukh, K W Michael Siu, Jeffrey C Smith, Richard D Smith, David J States, Sumio Sugano, Matthew Sullivan, Giulio Superti-Furga, Maarit Takatalo, Visith Thongboonkerd, Jonathan C Trinidad, Mathias Uhlen, Joël Vandekerckhove, Julian Vasilescu, Timothy D Veenstra, José-Manuel Vidal-Taboada, Mauno Vihinen, Robin Wait, Xiaoyue Wang, Stefan Wiemann, Billy Wu, Tao Xu, John R Yates, Jun Zhong, Ming Zhou, Yunping Zhu, Petra Zurbig & Akhilesh Pandey

doi:10.1038/nbt0208-164


Commentary

How biotech can transform biofuels pp169 - 172

Lee R Lynd, Mark S Laser, David Bransby, Bruce E Dale, Brian Davison, Richard Hamilton, Michael Himmel, Martin Keller, James D McMillan, John Sheehan & Charles E Wyman

doi:10.1038/nbt0208-169


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Features

Weighing the outcomes pp173 - 182

Michael J Russo & David Balekdjian

doi:10.1038/nbt0208-173


Patents

Recent Supreme Court decisions and licensing power pp183 - 185

Jennifer Giordano-Coltart & Charles W Calkins

doi:10.1038/nbt0208-183


Recent patent applications in gene expression p186

doi:10.1038/nbt0208-186


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News and Views

Stem cells in a new light pp187 - 188

Henry Klassen & Benjamin Reubinoff

doi:10.1038/nbt0208-187

See also: Research by Osakada et al.


A crystal clear view of the beta2-adrenergic receptor pp189 - 191

Robert J Lefkowitz, Jin-Peng Sun & Arun K Shukla

doi:10.1038/nbt0208-189


Regulating rejection with cell therapy pp191 - 192

Mohamed H Sayegh & Howard L Weiner

doi:10.1038/nbt0208-191


Research highlights p193

doi:10.1038/nbt0208-193


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Computational Biology

Primer

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Research

Perspective

Assessment of risk of insect-resistant transgenic crops to nontarget arthropods pp203 - 208

Jörg Romeis, Detlef Bartsch, Franz Bigler, Marco P Candolfi, Marco M C Gielkens, Susan E Hartley, Richard L Hellmich, Joseph E Huesing, Paul C Jepson, Raymond Layton, Hector Quemada, Alan Raybould, Robyn I Rose, Joachim Schiemann, Mark K Sears, Anthony M Shelton, Jeremy Sweet, Zigfridas Vaituzis & Jeffrey D Wolt

doi:10.1038/nbt1381


Insect resistance to Bt crops: evidence versus theory pp199 - 202

Bruce E Tabashnik, Aaron J Gassmann, David W Crowder & Yves Carriére

doi:10.1038/nbt1382


Brief Communications

Switching constant domains enhances agonist activities of antibodies to a thrombopoietin receptor pp209 - 211

Masayuki Kai, Kazuhiro Motoki, Hideaki Yoshida, Chie Emuta, Yukiko Chisaka, Kumi Tsuruhata, Chisato Endo, Mari Muto, Munetake Shimabe, Uichi Nishiyama, Tetsuya Hagiwara, Atsushi Matsumoto, Hiroshi Miyazaki & Shiro Kataoka

doi:10.1038/nbt1376


Human embryonic stem cell derivation from poor-quality embryos pp212 - 214

Paul H Lerou, Akiko Yabuuchi, Hongguang Huo, Ayumu Takeuchi, Jessica Shea, Tina Cimini, Tan A Ince, Elizabeth Ginsburg, Catherine Racowsky & George Q Daley

doi:10.1038/nbt1378


Article

Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells pp215 - 224

Fumitaka Osakada, Hanako Ikeda, Michiko Mandai, Takafumi Wataya, Kiichi Watanabe, Nagahisa Yoshimura, Akinori Akaike, Yoshiki Sasai & Masayo Takahashi

doi:10.1038/nbt1384

See also: News and Views by Klassen & Reubinoff


Article

Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection pp225 - 233

TuAnh Nguyen, Keishi Ishida, Holger Jenke-Kodama, Elke Dittmann, Cristian Gurgui, Thomas Hochmuth, Stefan Taudien, Matthias Platzer, Christian Hertweck & Jörn Piel

doi:10.1038/nbt1379


Letter

Fluorogen-activating single-chain antibodies for imaging cell surface proteins pp235 - 240

Christopher Szent-Gyorgyi, Brigitte F Schmidt, Yehuda Creeger, Gregory W Fisher, Kelly L Zakel, Sally Adler, James A J Fitzpatrick, Carol A Woolford, Qi Yan, Kalin V Vasilev, Peter B Berget, Marcel P Bruchez, Jonathan W Jarvik & Alan Waggoner

doi:10.1038/nbt1368


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Errata

Erratum: Allergenicity assessment of genetically modified crops—what makes sense? p241

Richard E Goodman, Stefan Vieths, Hugh A Sampson, David Hill, Motohiro Ebisawa, Steve L Taylor & Ronald van Ree

doi:10.1038/nbt0208-241a


Erratum: Europe's anti-GM stance to presage animal feed shortage? p241

Peter Mitchell

doi:10.1038/nbt0208-241b


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Corrigendum

Corrigendum: Therapeutic targeting of a stem cell niche p241

Gregor B Adams, Roderick P Martin, Ian R Alley, Karissa T Chabner, Kenneth S Cohen, Laura M Calvi, Henry M Kronenberg & David T Scadden

doi:10.1038/nbt0208-241c


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Naturejobs

Careers and Recruitment

People

People p246

doi:10.1038/nbt0208-246


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Open Innovation Challenges

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