1. Robert J. Lefkowitz is in the Departments of Medicine and Biochemistry and the Howard Hughes Medical Institute, Duke University Medical Center, Durham, North Carolina 27710, USA. e-mail: lefko001@receptor-biol.duke.edu
2. Jin-Peng Sun and Arun K. Shukla are in the Departments of Medicine and Biochemistry, Duke University Medical Center, Durham, North Carolina 27710, USA.

Abstract

The crystal structure of a second G protein–coupled receptor sheds light on these key pharmaceutical targets.

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