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Nature Biotechnology 26, 1206 (1 November 2008) | doi:10.1038/nbt1108-1206a

Amgen's bone blockbuster

Hayley Birch

Amgen has announced favorable results for its experimental osteoporosis drug Denosumab that suggest it could take on market leader Fosamax, Merck's successful small-molecule drug. In phase 3 trials, Denosumab reduced by two-thirds the instance of spine fractures in postmenopausal women with osteoporosis.