Figure 1 - The number of publications with keywords for nucleic acid detection and sequencing technologies.


From the following article

What would you do if you could sequence everything?

Avak Kahvejian, John Quackenbush & John F Thompson

Nature Biotechnology 26, 1125 - 1133 (2008)

doi:10.1038/nbt1494

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PubMed (http://www.ncbi.nlm.nih.gov/sites/entrez) was searched in two-year increments for key words and the number of hits plotted over time. For 2007–2008, results from January 1–March 31, 2008 were multiplied by four and added to those for 2007. Key words used were those listed in the legend except for new sequencing technologies ('next-generation sequencing' or 'high-throughput sequencing'), ChIP ('chromatin immunoprecipitation' or 'ChIP-Chip' or 'ChIP-PCR' or 'ChIP-Seq'), qPCR (TaqMan or qPCR or 'real-time PCR') and SNP analysis (SNPs or 'single-nucleotide polymorphisms' and not nitroprusside (nitroprusside is excluded because sodium nitroprusside is sometimes abbreviated as 'SNP' but is generally unrelated to genetics)).

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