Table 1


From the following article

Protein-protein interaction networks and biology—what's the connection?

Luke Hakes, John W Pinney, David L Robertson & Simon C Lovell

Nature Biotechnology 26, 69 - 72 (2008)

doi:10.1038/nbt0108-69

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Table 1. Statistics for the LC25 and the HC7 datasets, showing the effect of multiple validation on global network properties

NetworkLC-1LC-2LC-3HC-2HC-3

LC-1, LC-2 and LC-3 are literature-curated networks containing interactions observed in at least one, two or three different experimental studies, respectively. HC-2 and HC-3 contain high-confidence interactions observed at least twice and at least three times, respectively. Statistics are calculated for nodes in the largest connected component only. Degree, number of neighbors of a given node; diameter, length of the longest of all shortest paths between node pairs; eccentricity, length of the longest of all shortest paths between a given node and any other node; radius, minimum value of eccentricity over all nodes; clustering coefficient, proportion of possible edges between the neighbors of a given node that are actually present. Definitions and details of methods can be found in ref. 35.

Nodes3,2891,5289452,9981,628
Edges11,3342,8441,2749,2583,045
Connected components2890124101200
Percentage nodes in largest component98.079.436.391.855.7
Percentage edges in largest component99.689.947.398.375.8
Mean degree7.004.213.516.615.09
Diameter1219191530
Mean eccentricity8.1413.814.29.9822.2
Radius61010815
Mean shortest path length4.227.547.564.909.99
Mean clustering coefficient0.270.330.300.290.40
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