Figure 2 - Topological analysis of the literature-curated dataset of Reguly et al.25
From the following article
Protein-protein interaction networks and biology—what's the connection?
Luke Hakes, John W Pinney, David L Robertson & Simon C Lovell
Nature Biotechnology 26, 69 - 72 (2008)
doi:10.1038/nbt0108-69
This shows the connectivity of each protein versus its interacting partner(s) for the network composed of all LC interaction data (gray squares), interactions observed in at least two different experimental studies (open circles) and interactions observed in at least three different experimental studies (black triangles).