Perspective abstract


Nature Biotechnology 26, 73 - 81 (2008)
Published online: 8 January 2008 | doi:10.1038/nbt1343



There is an Erratum (February 2008) associated with this Perspective.

Allergenicity assessment of genetically modified crops—what makes sense?

Richard E Goodman1, Stefan Vieths2, Hugh A Sampson3, David Hill4, Motohiro Ebisawa5, Steve L Taylor1 & Ronald van Ree6


GM crops have great potential to improve food quality, increase harvest yields and decrease dependency on certain chemical pesticides. Before entering the market their safety needs to be scrutinized. This includes a detailed analysis of allergenic risks, as the safety of allergic consumers has high priority. However, not all tests currently being applied to assessing allergenicity have a sound scientific basis. Recent events with transgenic crops reveal the fallacy of applying such tests to GM crops.

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  1. Department of Food Science & Technology, University of Nebraska, Lincoln, Nebraska, 68583-0955, USA.
  2. Department of Allergology, Paul-Ehrlich-Institut, Langen, D-63225, Germany.
  3. Division of Pediatric Allergy and Immunology, Mount Sinai Medical Center, New York, New York, 10029, USA.
  4. Murdoch Children's Research Institute, Royal Children's Hospital, Melbourne, Victoria 3052, Australia.
  5. Division Pediatric Allergy, National Sagamihara Hospital, Sagamihara, 228-8522, Japan.
  6. Department of Experimental Immunology, Academic Medical Center, Amsterdam, 1105 AZ, The Netherlands.

Correspondence to: Richard E Goodman1 e-mail: rgoodman2@unlnotes.unl.edu



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