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Volume 26 Issue 1, January 2008

Human induced pluripotent stem cells expressing NANOG, a marker of embryonic stem cells. Yamanaka and colleagues generate induced pluripotent stem cells from mouse and human adult fibroblasts without using the c-Myc oncogene (p 101).

Editorial

  • Pressure is mounting on the US Food and Drug Administration (FDA) to explain its decision to ignore an advisory committee's positive recommendation for the cancer vaccine Provenge.

    Editorial

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News

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News in Brief

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Profile

  • Charismatic FasterCures president Greg Simon is on a mission to galvanize US biomedical research—and he's starting by changing attitudes to the sharing of donated patient materials.

    • Crispin Littlehales
    Profile
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Data Page

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News Feature

  • Follow-on biologics, changes to the patent system, new rules from the FDA and the prospect of a new party in the White House dominate the policy outlook for biotechs. Aaron Lorenzo reports.

    • Aaron Lorenzo
    News Feature
  • Investor activism hits the biotech industry with mixed results. Karl Thiel investigates.

    • Karl Thiel
    News Feature
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Correspondence

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Commentary

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Feature

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Patents

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News & Views

  • Induced pluripotent stem cells have been generated from mouse and human adult fibroblasts without the tumor-causing gene c-Myc.

    • Martin F Pera
    • Kouichi Hasegawa
    News & Views
  • A new mouse model with humanized blood vessels will facilitate testing of antiplatelet therapies.

    • Ingo Ahrens
    • Karlheinz Peter
    News & Views
  • The derivation of primate embryonic stem cells by nuclear transfer marks an advance toward human therapeutic cloning.

    • John Gurdon
    News & Views
  • Technologies for selecting segments of large genomes for resequencing will reveal biologically important sequence variation.

    • Michael Stratton
    News & Views
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Commentary

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Perspective

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Article

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Letter

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Research

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Careers and Recruitment

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People

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