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Volume 25 Issue 8, August 2007

Adult mouse liver stained with antibodies to the surface markers CD26 (green) and 2G9 (red). Azuma et al. describe a mouse model that allows engraftment and expansion of human hepatocytes. p 903.

Editorial

  • The example set by leading proteomics laboratories will be a major factor in determining the successful implementation of new reporting guidelines in the wider community.

    Editorial

    Advertisement

  • Despite hand-wringing over the patenting of a minimized organism, both patents and open-source approaches will be needed to promote innovation and research progress in synthetic biology.

    Editorial
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News

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News in Brief

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Data Page

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News Feature

  • When Zheng Xiaoyu took the helm of the Chinese State Food and Drug Administration (SFDA) nine years ago, hopes were high for effective regulatory oversight of China's drug industry. Now those hopes have been dashed with tragic personal consequences for Zheng and allegations of widespread corruption by Chinese officials.

    • Hepeng Jia
    News Feature
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Correspondence

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Commentary

  • An analysis of recent returns from venture-backed biotech firms reveals that companies receiving the most financing do not necessarily deliver the best returns.

    • Bruce L Booth
    Commentary
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Feature

  • As the cost of drug development continues to rise and public markets shift their attention to companies with late-stage products, an increasing diversity of financing options are becoming available to biotech companies with early-stage clinical programs.

    • Mark Kessel
    • Frederick Frank
    Feature
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Patents

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News & Views

  • A new mouse model allows mass production of human hepatocytes.

    • David A Shafritz
    News & Views
  • Evolved polymerases improve the recovery of ancient DNA.

    • M Thomas P Gilbert
    • Eske Willerslev
    News & Views
  • The nutritional quality of maize and soybean seeds is improved by embryo-specific silencing of an ABC transporter.

    • Victor Raboy
    News & Views
  • Peptides only 28 amino acids long retain the specificity of a parental antibody.

    • Robert Charles Ladner
    News & Views
  • Three recent papers on the reprogramming of somatic cells herald a revolution in stem cell biology.

    • Shin-ichi Nishikawa
    News & Views
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Primer

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Perspective

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Brief Communication

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Article

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Letter

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Erratum

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Corrigendum

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Careers and Recruitment

  • In the drug discovery industry, the key to managing innovation is to make the best use of scientists' creativity and build an innovation-fostering culture.

    • Xiaotian Zhong
    • George B Moseley III
    Careers and Recruitment
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People

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