News and Views
Nature Biotechnology 25, 743 - 744 (2007)
doi:10.1038/nbt0707-743
Precision genome surgery
Alfred Pingoud1 & George H Silva1
- Alfred Pingoud and George H. Silva are at the Institut fuer Biochemie, Fachbereich Biologie und Chemie, Justus-Liebig-Universitaet, Heinrich-Buff-Ring 58, D-35392 Giessen, Germany. e-mail: alfred.m.pingoud@chemie.bio.uni-giessen.de
Abstract
A redesign of zinc-finger nucleases reduces off-target cleavage.
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
RESEARCH
Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleasesNature Biotechnology Research (01 Jul 2007)
An improved zinc-finger nuclease architecture for highly specific genome editingNature Biotechnology Research (01 Jul 2007)
The monomeric homing endonuclease PI-SceI has two catalytic centres for cleavage of the two strands of its DNA substrateThe EMBO Journal Article (15 Dec 1999)
See all 8 matches for Research