News and Views

Nature Biotechnology 25, 743 - 744 (2007)
doi:10.1038/nbt0707-743

Precision genome surgery

Alfred Pingoud1 & George H Silva1

  1. Alfred Pingoud and George H. Silva are at the Institut fuer Biochemie, Fachbereich Biologie und Chemie, Justus-Liebig-Universitaet, Heinrich-Buff-Ring 58, D-35392 Giessen, Germany. e-mail: alfred.m.pingoud@chemie.bio.uni-giessen.de

A redesign of zinc-finger nucleases reduces off-target cleavage.

Top

MORE ARTICLES LIKE THIS

These links to content published by NPG are automatically generated.

RESEARCH

Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases

Nature Biotechnology Research (01 Jul 2007)

An improved zinc-finger nuclease architecture for highly specific genome editing

Nature Biotechnology Research (01 Jul 2007)

The monomeric homing endonuclease PI-SceI has two catalytic centres for cleavage of the two strands of its DNA substrate

The EMBO Journal Article (15 Dec 1999)

Gene targeting using zinc finger nucleases

Nature Biotechnology Research (01 Aug 2005)

See all 7 matches for Research

Extra navigation

See also

Search PubMed for

Open Innovation Challenges

  • Methods to Analyze Consumer Emotions

    • Deadline: Jan 17 2010
    • Reward: $10,000 USD

    The Seeker is looking for methods to analyze consumer emotions. This Challenge requires only a writ...

  • Single-cell Analysis Platform

    • Deadline: Dec 02 2009
    • Reward: $5,000 USD

    This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is...

naturejobs

More science jobs
Post a job for free

ADVERTISEMENT