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Volume 25 Issue 4, April 2007

Clausen and colleagues describe novel glycosidases that convert group A, B and AB blood to universal O-type blood (p 454). Extension of this technology to use in transfusion medicine will depend on performance in clinical trials and regulatory approval. Credit: Photo Researchers, Inc.

Editorial

  • In view of concerns about safety, could Amgen's aggressive promotion of erythropoietin (EPO) have jeopardized its billion-dollar franchise?

    Editorial

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News

  • The next wave of protein therapeutics, based on non-traditional scaffolds, may offer advantages in the range of conditions they can treat, delivery, and manufacturing. But they are just beginning to prove themselves in the clinic.

    • Cormac Sheridan
    News
  • A recent series of rulings from US federal courts speaks to the precarious legal state of current genetically modified crop activities.

    • Jeffrey L. Fox
    News
  • The UK's Office of Fair Trading is suggesting a system of drug pricing based on therapeutic value, which it believes would better focus innovation and investment toward creating more valuable drugs.

    • Nuala Moran
    News
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News in Brief

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News

  • John Maraganore is CEO of an increasingly rare breed of firm—the innovative science-based biotech.

    • Brady Huggett
    News
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News Feature

  • Neurotechnology companies have promise, but lack funding and credibility. Monya Baker reports on this nascent area for startups.

    • Monya Baker
    News Feature
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Correspondence

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Commentary

  • Other areas of biomedical research should emulate new standards from the International Society for Stem Cell Research highlighting the importance of sharing materials, data and research rights, and requiring fair global access to resulting diagnostics and therapies.

    • Patrick L Taylor
    Commentary
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Book Review

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Feature

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Patents

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News & Views

  • Novel glycosidases convert group A and B red blood cells to universal group O cells.

    • Geoff Daniels
    • Stephen G Withers
    News & Views
  • The sequence of the soil bacterium that synthesizes erythromycin A will aid efforts to boost antibiotic production.

    • Leonard Katz
    • Chaitan Khosla
    News & Views
  • Analysis of 50 million expressed sequence tags in rice reveals a complex collection of RNA species.

    • Antoni Rafalski
    News & Views
  • Live imaging reveals that caveolae mediate rapid transport of antibodies across the lung endothelium.

    • Kristy Red-Horse
    • Napoleone Ferrara
    News & Views
  • Recent studies of the 1918 influenza virus shed light on the risks of avian influenza virus.

    • Maria Zambon
    News & Views
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Commentary

  • The Brookhaven Protein Data Bank was once a pioneering database, but its organization of structural data is now outdated and in need of an upgrade.

    • Amanda C Schierz
    • Larisa N Soldatova
    • Ross D King
    Commentary
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Brief Communication

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Article

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Letter

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Erratum

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Corrigendum

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Careers and Recruitment

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People

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