Table of contents
Editorials
Flogging Gardasil - p261
doi:10.1038/nbt0307-261
Abstract - Flogging Gardasil | Full Text - Flogging Gardasil | PDF (67 KB) - Flogging Gardasil
Messing with home brews - p262
doi:10.1038/nbt0307-262a
Abstract - Messing with home brews | Full Text - Messing with home brews | PDF (38 KB) - Messing with home brews
Democratizing proteomics data - p262
doi:10.1038/nbt0307-262b
Abstract - Democratizing proteomics data | Full Text - Democratizing proteomics data | PDF (38 KB) - Democratizing proteomics data
News
Incretin mimetics vie for slice of type 2 diabetes market - p263
Catherine Shaffer
doi:10.1038/nbt0307-263
Abstract - Incretin mimetics vie for slice of type 2 diabetes market | Full Text - Incretin mimetics vie for slice of type 2 diabetes market | PDF (1,393 KB) - Incretin mimetics vie for slice of type 2 diabetes market
Supreme Court boosts licensees in biotech patent battles - pp264 - 265
Emily Waltz
doi:10.1038/nbt0307-264
Abstract - Supreme Court boosts licensees in biotech patent battles | Full Text - Supreme Court boosts licensees in biotech patent battles | PDF (70 KB) - Supreme Court boosts licensees in biotech patent battles
Public sector seeks to bridge 'valley of death' - p266
Nuala Moran
doi:10.1038/nbt0307-266
Abstract - Public sector seeks to bridge 'valley of death' | Full Text - Public sector seeks to bridge 'valley of death' | PDF (725 KB) - Public sector seeks to bridge 'valley of death'
US aims to tighten rules on direct-to-consumer drug ads - p267
Brian Vastag
doi:10.1038/nbt0307-267
Abstract - US aims to tighten rules on direct-to-consumer drug ads | Full Text - US aims to tighten rules on direct-to-consumer drug ads | PDF (1,121 KB) - US aims to tighten rules on direct-to-consumer drug ads
In Brief
News in brief - pp269 - 270
doi:10.1038/nbt0307-269
Data Page
Agbiotech booms in emerging nations - p271
Stacy Lawrence
doi:10.1038/nbt0307-271
Full Text - Agbiotech booms in emerging nations | PDF (145 KB) - Agbiotech booms in emerging nations
News Feature
Negotiating the RNAi patent thicket - pp273 - 275
Charlie Schmidt
doi:10.1038/nbt0307-273
Abstract - Negotiating the RNAi patent thicket | Full Text - Negotiating the RNAi patent thicket | PDF (1,935 KB) - Negotiating the RNAi patent thicket
Bioentrepreneur
Building a business
Becoming an American company: a holistic approach to decision making - pp277 - 280
Pradip K Banerjee
doi:10.1038/bioent916
PDF (122 KB) - Becoming an American company: a holistic approach to decision making
Opinion and Comment
Correspondence
Two views of the emperor's new clones - p281
Henry I Miller
doi:10.1038/nbt0307-281
Full Text - Two views of the emperor's new clones | PDF (263 KB) - Two views of the emperor's new clones
Two views of the emperor's new clones - pp282 - 283
David Schubert
doi:10.1038/nbt0307-282
Full Text - Two views of the emperor's new clones | PDF (839 KB) - Two views of the emperor's new clones
Biofuels and biocontainment - pp283 - 284
C Neal Stewart, Jr
doi:10.1038/nbt0307-283
Full Text - Biofuels and biocontainment | PDF (631 KB) - Biofuels and biocontainment
A curated compendium of phosphorylation motifs - pp285 - 286
Ramars Amanchy, Balamurugan Periaswamy, Suresh Mathivanan, Raghunath Reddy, Sudhir Gopal Tattikota & Akhilesh Pandey
doi:10.1038/nbt0307-285
Full Text - A curated compendium of phosphorylation motifs | PDF (514 KB) - A curated compendium of phosphorylation motifs | Supplementary information
Features
Overhauling clinical trials - pp287 - 292
Christopher Thomas Scott & Monya Baker
doi:10.1038/nbt0307-287
Abstract - Overhauling clinical trials | Full Text - Overhauling clinical trials | PDF (187 KB) - Overhauling clinical trials
Patents
The threat from within: trade secret theft by employees - pp293 - 295
Sharon Mollman Elliott
doi:10.1038/nbt0307-293
Abstract - The threat from within: trade secret theft by employees | Full Text - The threat from within: trade secret theft by employees | PDF (419 KB) - The threat from within: trade secret theft by employees
Recent patent applications in RNA interference - p296
doi:10.1038/nbt0307-296
Full Text - Recent patent applications in RNA interference | PDF (36 KB) - Recent patent applications in RNA interference
News and Views
Sequence-activity relationships guide directed evolution - pp297 - 298
Joelle N Pelletier & Robert Lortie
doi:10.1038/nbt0307-297
Abstract - Sequence-activity relationships guide directed evolution | Full Text - Sequence-activity relationships guide directed evolution | PDF (180 KB) - Sequence-activity relationships guide directed evolution
See also: Research by Fox et al.
Towards quantitative analysis of proteome dynamics - pp298 - 300
Sebastian Kühner & Anne-Claude Gavin
doi:10.1038/nbt0307-298
Abstract - Towards quantitative analysis of proteome dynamics | Full Text - Towards quantitative analysis of proteome dynamics | PDF (221 KB) - Towards quantitative analysis of proteome dynamics
See also: Research by Rinner et al.
Promoting angiogenesis to a fault - pp300 - 302
Daniel J Hicklin
doi:10.1038/nbt0307-300
Abstract - Promoting angiogenesis to a fault | Full Text - Promoting angiogenesis to a fault | PDF (715 KB) - Promoting angiogenesis to a fault
RNA interference has second helpings - pp302 - 303
Eric A Miska & Julie Ahringer
doi:10.1038/nbt0307-302
Abstract - RNA interference has second helpings | Full Text - RNA interference has second helpings | PDF (614 KB) - RNA interference has second helpings
Toll-free vaccines? - pp303 - 305
Arthur M Krieg
doi:10.1038/nbt0307-303
Abstract - Toll-free vaccines? | Full Text - Toll-free vaccines? | PDF (890 KB) - Toll-free vaccines?
Research Highlights - p307
doi:10.1038/nbt0307-307
Full Text - Research Highlights | PDF (101 KB) - Research Highlights
Computational Biology
Analysis
A human phenome-interactome network of protein complexes implicated in genetic disorders - pp309 - 316
Kasper Lage, E Olof Karlberg, Zenia M Størling, Páll Í Ólason, Anders G Pedersen, Olga Rigina, Anders M Hinsby, Zeynep Tümer, Flemming Pociot, Niels Tommerup, Yves Moreau & Søren Brunak
doi:10.1038/nbt1295
Abstract - A human phenome-interactome network of protein complexes implicated in genetic disorders | Full Text - A human phenome-interactome network of protein complexes implicated in genetic disorders | PDF (767 KB) - A human phenome-interactome network of protein complexes implicated in genetic disorders | Supplementary information
Brief Communication
Endothelial cells derived from human embryonic stem cells form durable blood vessels in vivo - pp317 - 318
Zack Z Wang, Patrick Au, Tong Chen, Ying Shao, Laurence M Daheron, Hao Bai, Melanie Arzigian, Dai Fukumura, Rakesh K Jain & David T Scadden
doi:10.1038/nbt1287
Abstract - Endothelial cells derived from human embryonic stem cells form durable blood vessels : in vivo | Full Text - Endothelial cells derived from human embryonic stem cells form durable blood vessels in vivo | PDF (221 KB) - Endothelial cells derived from human embryonic stem cells form durable blood vessels in vivo | Supplementary information
Research
Articles
Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis - pp319 - 326
Thomas W Jeffries, Igor V Grigoriev, Jane Grimwood, José M Laplaza, Andrea Aerts, Asaf Salamov, Jeremy Schmutz, Erika Lindquist, Paramvir Dehal, Harris Shapiro, Yong-Su Jin, Volkmar Passoth & Paul M Richardson
doi:10.1038/nbt1290
Abstract - Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast : Pichia stipitis | Full Text - Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis | PDF (420 KB) - Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis | Supplementary information
Live dynamic imaging of caveolae pumping targeted antibody rapidly and specifically across endothelium in the lung - pp327 - 337
Phil Oh, Per Borgström, Halina Witkiewicz, Yan Li, Bengt J Borgström, Adrian Chrastina, Koji Iwata, Kurt R Zinn, Richard Baldwin, Jacqueline E Testa & Jan E Schnitzer
doi:10.1038/nbt1292
Abstract - Live dynamic imaging of caveolae pumping targeted antibody rapidly and specifically across endothelium in the lung | Full Text - Live dynamic imaging of caveolae pumping targeted antibody rapidly and specifically across endothelium in the lung | PDF (1,167 KB) - Live dynamic imaging of caveolae pumping targeted antibody rapidly and specifically across endothelium in the lung | Supplementary information
Improving catalytic function by ProSAR-driven enzyme evolution - pp338 - 344
Richard J Fox, S Christopher Davis, Emily C Mundorff, Lisa M Newman, Vesna Gavrilovic, Steven K Ma, Loleta M Chung, Charlene Ching, Sarena Tam, Sheela Muley, John Grate, John Gruber, John C Whitman, Roger A Sheldon & Gjalt W Huisman
doi:10.1038/nbt1286
Abstract - Improving catalytic function by ProSAR-driven enzyme evolution | Full Text - Improving catalytic function by ProSAR-driven enzyme evolution | PDF (393 KB) - Improving catalytic function by ProSAR-driven enzyme evolution | Supplementary information
See also: News and Views by Pelletier & Lortie
An integrated mass spectrometric and computational framework for the analysis of protein interaction networks - pp345 - 352
Oliver Rinner, Lukas N. Mueller, Martin Hubálek, Markus Müller, Matthias Gstaiger & Ruedi Aebersold
doi:10.1038/nbt1289
Abstract - An integrated mass spectrometric and computational framework for the analysis of protein interaction networks | Full Text - An integrated mass spectrometric and computational framework for the analysis of protein interaction networks | PDF (337 KB) - An integrated mass spectrometric and computational framework for the analysis of protein interaction networks | Supplementary information
See also: News and Views by Kühner & Gavin
Letter
Female-specific insect lethality engineered using alternative splicing - pp353 - 357
Guoliang Fu, Kirsty C Condon, Matthew J Epton, Peng Gong, Li Jin, George C Condon, Neil I Morrison, Tarig H Dafa'alla & Luke Alphey
doi:10.1038/nbt1283
First paragraph - Female-specific insect lethality engineered using alternative splicing | Full Text - Female-specific insect lethality engineered using alternative splicing | PDF (224 KB) - Female-specific insect lethality engineered using alternative splicing | Supplementary information
Naturejobs
Careers and Recruitment
Research training and academic disciplines at the convergence of nanotechnology and biomedicine in the United States - pp359 - 361
Kelly Y Kim
doi:10.1038/nbt0307-359
Abstract - Research training and academic disciplines at the convergence of nanotechnology and biomedicine in the United States | Full Text - Research training and academic disciplines at the convergence of nanotechnology and biomedicine in the United States | PDF (116 KB) - Research training and academic disciplines at the convergence of nanotechnology and biomedicine in the United States | Supplementary information
