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Calreticulin exposure increases cancer immunogenicity

Nature Biotechnology volume 25, pages 192–193 (2007)Cite this article

Some cytotoxic anticancer drugs may boost an immunogenic molecular signal of apoptosis.

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Figure 1: The impact of a dying cell on immune function is governed by phagocytic uptake.

Kim Caesar

References

  1. Casares, N. et al. J. Exp. Med. 202, 1691–1701 (2005).

    Article  CAS  Google Scholar 

  2. Obeid, M. et al. Nat. Med. 13, 52–59 (2006).

    Google Scholar 

  3. Zong, W.X. & Thompson, C.B. Genes Dev. 20, 1–15 (2006).

    Article  CAS  Google Scholar 

  4. Krysko, D.V., D'Herde, K. & Vandenabeele, P. Apoptosis 11, 1709–1726 (2006).

    Article  Google Scholar 

  5. Henson, P.M., Bratton, D.L. & Fadok, V.A. Nat. Rev. Mol. Cell Biol. 2, 627–633 (2001).

    Article  CAS  Google Scholar 

  6. Drake, C.G., Jaffee, E. & Pardoll, D.M. Adv. Immunol. 90, 51–81 (2006).

    Article  CAS  Google Scholar 

  7. Davis, I.D., Jefford, M., Parente, P. & Cebon, J. J. Leukoc. Biol. 73, 3–29 (2003).

    Article  CAS  Google Scholar 

  8. Lake, R.A. & van der Most, R.G. N. Engl. J. Med. 354, 2503–2504 (2006).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Chris Clarke and Mark J. Smyth are with the Cancer Immunology Program, Peter MacCallum Cancer Centre, St Andrews Place, East Melbourne, Victoria 3002, Australia. chris.clarke@petermac.org or mark.smyth@petermac.org,

    Chris Clarke & Mark J Smyth

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  1. Chris Clarke
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  2. Mark J Smyth
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Clarke, C., Smyth, M. Calreticulin exposure increases cancer immunogenicity. Nat Biotechnol 25, 192–193 (2007). https://doi.org/10.1038/nbt0207-192

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