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Nature Biotechnology 25, 1395–1402 (1 December 2007) | doi:10.1038/nbt1207-1395

Antivirals become a broader enterprise

Jeffrey L Fox

Efforts to develop antiviral therapeutics had mostly sputtered before the AIDS epidemic spurred an intensive search for new drugs to counter the human immunodeficiency virus (HIV). Added impetus has been provided by the frustrations and failures encountered during HIV vaccine development (Box 1).