Figure 1 - HIV life cycle.

From the following article

Genetic therapies against HIV

John J Rossi, Carl H June & Donald B Kohn

Nature Biotechnology 25, 1444 - 1454 (2007) Published online: 7 December 2007

doi:10.1038/nbt1367

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(1) HIV binds to CD4 and co-receptors CCR5 and CXCR4 and is internalized. (2) Uncoating of virus. (3) Reverse transcription. (4) Integration into host chromosomal DNA. (5) Expression of early viral proteins from multiply spliced mRNAs. (6) Expression of late mRNAs encoding the structural proteins Env, Gag, Pol and integrase. (7) Packaging of unspliced genomic RNA and release of viral particles.

Katie Ris-Vicari

Figures and tables index
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