Table 2


From the following article

Albinterferon alpha-2b: a genetic fusion protein for the treatment of chronic hepatitis C

G Mani Subramanian, Michele Fiscella, Araba Lamousé-Smith, Stefan Zeuzem & John G McHutchison

Nature Biotechnology 25, 1411 - 1419 (2007) Published online: 7 December 2007

doi:10.1038/nbt1364

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Table 2. Clinical studies with albumin-fusion products

Albumin-fusion productsFusion partner MW (kDa)Development-stageIndication
Alb-growth hormone (GH)22Phase 1/2Growth hormone deficiency
Alb-granulocyte colony-stimulating factor (GCSF)19.6Phase 1/2Neutropenia
Alb-interferon (IFN-alpha)19.2Phase 3Chronic hepatitis C
Alb-interleukin 2 (IL2)15.5Phase 1/2Malignancy
Alb-glucagon-like peptide 1 (GLP-1)3.8Phase 1/2Diabetes mellitus
Alb-beta-natriuretic peptide (BNP)3.5Phase 1/2Congestive heart failure
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