Figure 1 - Clonal human AFS cells have a normal karyotype and retain long telomeres.
From the following article
Isolation of amniotic stem cell lines with potential for therapy
Paolo De Coppi, Georg Bartsch, Jr, M Minhaj Siddiqui, Tao Xu, Cesar C Santos, Laura Perin, Gustavo Mostoslavsky, Angéline C Serre, Evan Y Snyder, James J Yoo, Mark E Furth, Shay Soker & Anthony Atala
Nature Biotechnology 25, 100 - 106 (2007) Published online: 7 January 2007
doi:10.1038/nbt1274
(a) Giemsa band karyogram showing chromosomes of late passage (>250 p.d.) cells. (b) Flow cytometry of late passage cells showing DNA stained with propidium iodide. G1 and G2/M indicate 2n and 4n cellular DNA content, respectively. S indicates cells undergoing DNA synthesis, intermediate in DNA content between 2n and 4n. (c) Conserved telomere length of AFS cells between early passage (20 p.d., lane 3) and late passage (250 p.d., lane 4). Short length (lane 1) and high length (lane 2) telomere standards are provided in the assay kit. Marker lengths are indicated. p.d., population doubling.
