Nature Biotechnology
- 24, 959 - 961 (2006)
doi:10.1038/nbt0806-959
How does DNA sequence motif discovery work?Patrik D'haeseleer
Patrik D'haeseleer is in the Microbial Systems Division, Biosciences Directorate, Lawrence Livermore National Laboratory, 7000 East Ave., PO Box 808, L-448, Livermore, California 94551, USA. patrikd@llnl.gov
How can we computationally extract an unknown motif from a set of target sequences? What are the principles behind the major motif discovery algorithms? Which of these should we use, and how do we know we've found a 'real' motif?
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