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Nature Biotechnology 24, 697 - 702 (2006)
Published online: 14 May 2006; | doi:10.1038/nbt1211

Short hairpin RNA–expressing bacteria elicit RNA interference in mammals

Shuanglin Xiang, Johannes Fruehauf & Chiang J Li

Supplementary Fig. 1 (pdf 20K)
Structure of Transkingdom RNA Interference Plasmid (TRIP) and silencing sequences

Supplementary Fig. 2 (pdf 24K)
Specific silencing of beta-catenin in SW 480 cells

Supplementary Fig. 3 (pdf 40K)
Silencing is caused by bacterial produced shRNA; TRIP plasmid transfection does not induce silencing.

Supplementary Fig. 4 (pdf 368K)
GAPDH expression is not altered by E.coli expressing shRNA against beta-catenin after oral dosing in mice

Supplementary Table 1 (pdf 16K)
RT-PCR for marker genes of interferon pathway induction


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Nature Biotechnology
ISSN: 1087-0156
EISSN: 1546-1696
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