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Volume 24 Issue 2, February 2006

Colored scanning electron micrograph of Streptococcus pyogenes, a group A Streptococcus that can cause multiple infections in humans. Grandi and colleagues describe a proteomic approach to identifying novel antigens for the development of vaccines against this group of organisms, p 191. Credit: Eye of Science/Photo Researchers, Inc.

Volume 24 Issue 2

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  • The faculty director of the newly established bioethics center at Harvard Law School believes that law is the framework for looking at all the issues relevant to the delivery of healthcare, from malpractice to insurance to patents.

    • Mark Ratner
    Profile
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Data Page

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News Feature

  • Cancer drugs targeting signaling pathways have been hampered by problems of efficacy and tumor resistance. Will the next generation of kinase inhibitors fare better than the first? Ken Garber investigates.

    • Ken Garber
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Correspondence

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Commentary

  • Poor national mechanisms for accountability, competition, transparency and ethical oversight allowed Hwang Woo-Suk's descent into ethical, and ultimately scientific, misconduct.

    • Herbert Gottweis
    • Robert Triendl
    Commentary
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Investors Lab

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  • If there's a positive message to take away from the FDA's seemingly endless troubles in 2005, it may be that smaller companies are increasingly registering on the agency's radar.

    • Mark Ratner
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Patents

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News & Views

  • Directed evolution of adeno-associated virus (AAV) yields mutant vectors that can evade neutralizing antibodies.

    • Aravind Asokan
    • R Jude Samulski
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  • Human embryonic stem cell lines are derived under defined conditions.

    • Harry Moore
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  • Another toxic explosive is now amenable to phytoremediation, but the political will to implement this technology remains in doubt.

    • Richard B Meagher
    News & Views
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