Nature Biotechnology
- 24, 1429 - 1435 (2006)
Published online: 24 September 2006; | doi:10.1038/nbt1246
Compact, universal DNA microarrays to comprehensively determine transcription-factor binding site specificitiesMichael F Berger, Anthony A Philippakis, Aaron M Qureshi, Fangxue S He, Preston W Estep III & Martha L Bulyk Supplementary Fig. 1 (pdf 572K) Survey of binding sites in the JASPAR database. Supplementary Fig. 2 (pdf 516K) Reproducibility of Cy3 dUTP signal intensities. Supplementary Fig. 3 (pdf 680K) Correlation of PBM signal intensities with affinities. Supplementary Fig. 4 (pdf 632K) Effects of binding site position and orientation on PBM signal. Supplementary Fig. 5 (pdf 656K) Comparison of median signal intensities for 28 Zif268 variants for fixed versus variable position, orientation, and flanking sequence. Supplementary Fig. 6 (pdf 300K) Correspondence between median signal intensities for 7-mers on distinct de Bruijn sequences. Supplementary Fig. 7 (pdf 924K) Biacore measurements supporting interdependence between the first two positions of the Cbf1 binding site. Supplementary Fig. 8 (pdf 656K) Minimum number of unique features on an array for different values of k. Supplementary Fig. 9 (pdf 612K) Dependence of Cy3 dUTP incorporation upon sequence context. Supplementary Methods (doc 76K)
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