Table of contents


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News

Genentech raises stakes on PARP inhibitors pp1179 - 1180

Cormac Sheridan

doi:10.1038/nbt1006-1179


Polyclonal antibodies step out of the shadows p1181

Emily Waltz

doi:10.1038/nbt1006-1181


Poor enforcement could jeopardize China's drug innovation policy pp1182 - 1183

Hepeng Jia

doi:10.1038/nbt1006-1182


Brazil next biotech trailblazer in Latin America? p1184

Ricardo Bonalume

doi:10.1038/nbt1006-1184


In Brief

News In Brief pp1186 - 1187

doi:10.1038/nbt1006-1186


Profile: Michael Fernandez p1188

Kendall Powell

doi:10.1038/nbt1006-1188


Data Page

Biotech patenting upturn p1190

Stacy Lawrence

doi:10.1038/nbt1006-1190


News Feature

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Bioentrepreneur

Building a business

Exit strategies in Europe pp1195 - 1197

Peter Buckel, Ulrich Dauer, Patrik Frei & Jean-Yves Nothias

doi:10.1038/bioent911


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Opinion and Comment

Correspondence

Reactions to Eprex's adverse reactions pp1199 - 1200

Basant Sharma, Mary H. Ryan & Katia Boven

doi:10.1038/nbt1006-1199


Reply to Reactions to Eprex's adverse reactions p1200

doi:10.1038/nbt1006-1200a


Potential impact and cost-effectiveness of Golden Rice pp1200 - 1201

Alexander J Stein, H.P.S. Sachdev & Matin Qaim

doi:10.1038/nbt1006-1200b


Commentary

The imitation game—a computational chemical approach to recognizing life pp1203 - 1206

Leroy Cronin, Natalio Krasnogor, Benjamin G Davis, Cameron Alexander, Neil Robertson, Joachim H G Steinke, Sven L M Schroeder, Andrei N Khlobystov, Geoff Cooper, Paul M Gardner, Peter Siepmann, Benjamin J Whitaker & Dan Marsh

doi:10.1038/nbt1006-1203


Investor's Lab

Biotech buybacks—good or bad? p1207

Tom Jacobs

doi:10.1038/nbt1006-1207


Book Review

Relighting the Enlightenment p1209

doi:10.1038/nbt1006-1209


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Features

The emerging nanomedicine landscape pp1211 - 1217

Volker Wagner, Anwyn Dullaart, Anne-Katrin Bock & Axel Zweck

doi:10.1038/nbt1006-1211


Patents

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News and Views

Putting proteins on the map pp1223 - 1224

Robert F Murphy

doi:10.1038/nbt1006-1223

See also: Research by Schubert et al.





Wastewater genomics pp1229 - 1230

Takashi Mino & Hiroyasu Satoh

doi:10.1038/nbt1006-1229

See also: Research by Martín et al.



Research Highlights p1233

doi:10.1038/nbt1006-1233


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Computational Biology

Analysis

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Research

Perspective

Brief Communications

Articles

Genome sequence of the bioplastic-producing "Knallgas" bacterium Ralstonia eutropha H16 pp1257 - 1262

Anne Pohlmann, Wolfgang Florian Fricke, Frank Reinecke, Bernhard Kusian, Heiko Liesegang, Rainer Cramm, Thomas Eitinger, Christian Ewering, Markus Pötter, Edward Schwartz, Axel Strittmatter, Ingo Vos zlig, Gerhard Gottschalk, Alexander Steinbüchel, Bärbel Friedrich & Botho Bowien

doi:10.1038/nbt1244

See also: News and Views by Lee


Metagenomic analysis of two enhanced biological phosphorus removal (EBPR) sludge communities pp1263 - 1269

Héctor García Martín, Natalia Ivanova, Victor Kunin, Falk Warnecke, Kerrie W Barry, Alice C McHardy, Christine Yeates, Shaomei He, Asaf A Salamov, Ernest Szeto, Eileen Dalin, Nik H Putnam, Harris J Shapiro, Jasmyn L Pangilinan, Isidore Rigoutsos, Nikos C Kyrpides, Linda Louise Blackall, Katherine D McMahon & Philip Hugenholtz

doi:10.1038/nbt1247

See also: News and Views by Mino & Satoh


Analyzing proteome topology and function by automated multidimensional fluorescence microscopy pp1270 - 1278

Walter Schubert, Bernd Bonnekoh, Ansgar J Pommer, Lars Philipsen, Raik Böckelmann, Yanina Malykh, Harald Gollnick, Manuela Friedenberger, Marcus Bode & Andreas W M Dress

doi:10.1038/nbt1250

See also: News and Views by Murphy


Letters

Human C5aR knock-in mice facilitate the production and assessment of anti-inflammatory monoclonal antibodies pp1279 - 1284

Hyun Lee, David Zahra, Alexis Vogelzang, Rebecca Newton, Jenny Thatcher, Annie Quan, Trina So, Jörg Zwirner, Frank Koentgen, Søren B Padkjær, Fabienne Mackay, Peter L Whitfeld & Charles R Mackay

doi:10.1038/nbt1248

See also: News and Views by Wang



Erratum

Erratum: High-resolution computational models of genome binding events p1293

Yuan Qi, Alex Rolfe, Kenzie D MacIsaac, Georg K Gerber, Dmitry Pokholok, Julia Zeitlinger, Timothy Danford, Robin D Dowell, Ernest Fraenkel, Tommi S Jaakkola, Richard A Young & David K Gifford

doi:10.1038/nbt1006-1293a


Corrigenda

Corrigendum: Tumor antigen—specific induction of transcriptionally targeted retroviral vectors from chimeric immune receptor—modified T cells p1293

John Chester, Anja Ruchatz, Michael Gough, Marka Crittenden, Heung Chong, François Loïc-Cosset, Rosa Maria Diaz, Kevin Harrington, Luis Alvarez-Vallina & Richard Vile

doi:10.1038/nbt1006-1293b


Corrigendum: Integrative model of the response of yeast to osmotic shock p1293

Edda Klipp, Bodil Nordlander, Roland Krüger, Peter Gennemark & Stefan Hohmann

doi:10.1038/nbt1006-1293c


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Naturejobs

Careers and Recruitment

People

People p1298

doi:10.1038/nbt1006-1298


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