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Map of 15 epitopes in a primary human hepatocyte, analyzed and visualized by multi-epitope-ligand cartography (MELC). In this issue, Schubert and colleagues introduce MELC as a means of mapping large numbers of molecular components at subcellular resolution in single cells and tissue sections (p 1270). Image courtesy of Walter Schubert.
With a healthy dose of skepticism and a penchant for science policy, Michael Fernandez wades into the contentious issue of agricultural biotech regulation. He talks about how to move a polarized debate forward and the constant challenge of remaining neutral in Washington, DC.
Nothing in US patent law has a more drastic effect on an inventor's patent than a finding of inequitable conduct, so understanding the principles of the doctrine can be valuable in saving your patent from being found unenforceable.
This supplement collects together reprints of papers from Nature Biotechnology reporting the first formal results of a consortium of over 150 regulatory, industrial and academic scientists that set out to conduct a cross-platform analysis of DNA microarray expression data obtained from two, commercially available RNA samples.