Volume 24 Issue 1, January 2006

Editorial

Getting beyond Hwang

Editorial 01 Jan 2006

Advertisement
Genetically modified mush

Editorial 01 Jan 2006

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News

Biotech jostles with pharma for slice of HIV market

Entry inhibitors offer an alternative strategy to treat AIDS.

Alla Katsnelson
News 05 Jan 2006
Serono changes tack

What appears to be Serono's imminent departure from the ranks of biotech, could be another phase in the maturation of the continent's pharmaceutical sector.

Cormac Sheridan
News 05 Jan 2006
Shift toward early-stage deals favors biotechs

As biopharmaceutical companies move further into the pipeline in search of candidates, early stage deals are increasing in number and value.

Stacy Lawrence
News 05 Jan 2006
Lack of private financing hobbles emerging biotech regions

The availability of private funding remains an important but elusive factor for success

Hepeng Jia
K.S. Jayarama
Marina Astvatsaturyan
News 05 Jan 2006

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News in Brief

News In Brief

News in Brief 05 Jan 2006

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Data Page

Tech transfer revs up

Stacy Lawrence
Data Page 05 Jan 2006

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Correspondence

Wrestling with SUMO and bio-ontologies

Mark A. Musen
Suzanna Lewis
Barry Smith
Correspondence 01 Jan 2006
Wrestling with SUMO and bio-ontologies

Christian Stoeckert
Catherine Ball
Joseph White
Correspondence 01 Jan 2006
Wrestling with SUMO and bio-ontologies

Mark Miller
Rami Rifaieh
Correspondence 01 Jan 2006
Reply to Wrestling with SUMO and bio-ontologies

Correspondence 01 Jan 2006
European GMO labeling thresholds impractical and unscientific

Florian Weighardt
Correspondence 01 Jan 2006
ATCC not involved in negotiations with India

Jesus Soriano
Correspondence 01 Jan 2006

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Commentary

Activism unleashed...and unconscionable

How activists play on our fears about pharmaceutical and biotech companies.

Henry I Miller
Commentary 01 Jan 2006

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Investors Lab

Paying over the odds

Tom Jacobs
Investors Lab 01 Jan 2006

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Book Review

Clone aid

Arthur L. Caplan
Book Review 01 Jan 2006

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Feature

The licensing of DNA patents by US academic institutions: an empirical survey

A survey of technology transfer of DNA inventions at 19 top US research universities reveals consensus, diversity and flexibility in intellectual property management. Patent filing and license terms are influenced by intended uses of inventions, outside market interest and NIH guidelines.

Lori Pressman
Richard Burgess
LeRoy Walters
Feature 01 Jan 2006

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Patents

Determining the meaning of claim terms

In Phillips v. AWH, the US Federal Circuit clarifies the importance of defining a claim in the context of the entire patent rather than relying on outside sources.

Henry E Auer
Patents 01 Jan 2006
Recent patent applications in microRNAs

Patents 01 Jan 2006

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News & Views

Fishing for cancer models

A comparative study of gene expression in hepatocellular carcinomas underscores the utility of zebrafish for human cancer research.

Clemens Grabher
A Thomas Look
News & Views 01 Jan 2006
Steroid regulation improves crop yield

Slight decreases in brassinosteroid levels help rice plants make the most of daylight.

Kenneth A Feldmann
News & Views 01 Jan 2006
RNAi tackles a sexually transmitted disease

RNA therapy is effective against Herpes simplex virus-2 in mice.

Patricia Cristofaro
Bharat Ramratnam
News & Views 01 Jan 2006
Research Highlights

News & Views 01 Jan 2006

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Primer

Inference in Bayesian networks

Bayesian networks are increasingly important for integrating biological data and for inferring cellular networks and pathways. What are Bayesian networks and how are they used for inference?

Chris J Needham
James R Bradford
David R Westhead

Collection:

Computational Biology
Primer 01 Jan 2006

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Analysis

Creation and implications of a phenome-genome network

Atul J Butte
Isaac S Kohane
Analysis 10 Jan 2006

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Perspective

Transgenic crops expressing Bacillus thuringiensis toxins and biological control

Jörg Romeis
Michael Meissle
Franz Bigler
Perspective 10 Jan 2006

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Brief Communication

Conservation of gene expression signatures between zebrafish and human liver tumors and tumor progression

Siew Hong Lam
Yi Lian Wu
Zhiyuan Gong
Brief Communication 04 Dec 2005
Production of a recombinant bacterial lipoprotein in higher plant chloroplasts

Karin Glenz
Bernadette Bouchon
Heribert Warzecha
Brief Communication 04 Dec 2005

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Article

Engineering and characterization of a superfolder green fluorescent protein

Jean-Denis Pédelacq
Stéphanie Cabantous
Geoffrey S Waldo

Collection:

Fluorescent protein biosensors
Article 20 Dec 2005

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Letter

A genetic strategy to treat sickle cell anemia by coregulating globin transgene expression and RNA interference

Selda Samakoglu
Leszek Lisowski
Michel Sadelain
Letter 25 Dec 2005
A genetically encoded photosensitizer

Maria E Bulina
Dmitriy M Chudakov
Konstantin A Lukyanov
Letter 20 Dec 2005
Extracellular accumulation of recombinant proteins fused to the carrier protein YebF in Escherichia coli

Guijin Zhang
Stephen Brokx
Joel H Weiner
Letter 20 Dec 2005
Erect leaves caused by brassinosteroid deficiency increase biomass production and grain yield in rice

Tomoaki Sakamoto
Yoichi Morinaka
Makoto Matsuoka
Letter 20 Dec 2005

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Careers and Recruitment

Thinking outside the cell

New tools and technologies are allowing cell biologists to take a more holistic view. To make the most of this, they are teaming up with scientists from other fields.

Corie Lok
Careers and Recruitment 01 Jan 2006

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People

People

People 01 Jan 2006

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Volume 24 Issue 1, January 2006

Editorial

News

News in Brief

Data Page

Correspondence

Commentary

Investors Lab

Book Review

Feature

Patents

News & Views

Primer

Analysis

Perspective

Brief Communication

Article

Letter

Careers and Recruitment

People

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