Nature Biotechnology
23, 942 - 944 (2005)
doi:10.1038/nbt0805-942
Discovering DNA regulatory elements with bacteriaMartha L Bulyk
Martha L. Bulyk is in the Division of Genetics, Department of Medicine, Department of Pathology and the Harvard-MIT Division of Health Sciences & Technology, Brigham & Women's Hospital and Harvard Medical School, Harvard Medical School New Research Building, Room 466D, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA. mlbulyk@receptor.med.harvard.edu
A bacterial one-hybrid selection system offers a low-tech alternative for determining the DNA-binding specificities of transcription factors.
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