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| In This Issue |  Top |
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| Editorial | Top |
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Memo to FDA head: IT upgrade required p507
doi:10.1038/nbt0505-507
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(58K)
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| News | Top |
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Earlier stage biotechs attract partners p509
Mark Ratner
doi:10.1038/nbt0505-509
Abstract | Full text | PDF
(90K)
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Cautious welcome for FDA pharmacogenomics guidance p510
Alla Katsnelson
doi:10.1038/nbt0505-510
Abstract | Full text | PDF
(88K)
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EPO neem patent revocation revives biopiracy debate pp511 - 512
Cormac Sheridan
doi:10.1038/nbt0505-511
Abstract | Full text | PDF
(143K)
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US court case to define EST patentability p513
Stacy Lawrence
doi:10.1038/nbt0505-513
Abstract | Full text | PDF
(194K)
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Syngenta's gaff embarrasses industry and White House p514
Stephan Herrera
doi:10.1038/nbt0505-514
Abstract | Full text | PDF
(88K)
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| In Brief |
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News In Brief pp515 - 516
doi:10.1038/nbt0505-515
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(130K)
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Profile: Julian Thurston p517
Sabine Louët
doi:10.1038/nbt0505-517
Abstract | Full text | PDF
(57K)
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| Data Page |
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Mixed results in Q1 p518
Stacy Lawrence
doi:10.1038/nbt0505-518
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(117K)
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| News Feature |
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Gene therapy: cursed or inching towards credibility? pp519 - 521
Malorye A. Branca
doi:10.1038/nbt0505-519
Abstract | Full text | PDF
(171K)
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| Bioentrepreneur | Top |
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| Bioenews |
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India's strategy to bridge the public-private divide p523
K.S. Jayaraman
Published online: 07 April 2005 | doi:10.1038/bioent857
Reprinted with some modification from the Bioentrepreneur web portal (http://www.nature.com/bioent)
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(104K)
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| Building a business |
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The role of competitive intelligence in biotech startups pp525 - 527
Salvador Carlucci, Anthony Page
& David Finegold
Published online: 21 March 2005 | doi:10.1038/bioent850
Reprinted with some modification from the Bioentrepreneur web portal (http://www.nature.com/bioent)
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(51K)
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| Opinion and Comment | Top |
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| Correspondence |
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The origins of new drugs pp529 - 530
Robert Kneller
doi:10.1038/nbt0505-529
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(38K)
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Framing the issues on transgenic forests pp530 - 532
Claire G. Williams
doi:10.1038/nbt0505-530
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(166K)
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Lost in the woods pp532 - 533
Sofia Valenzuela
& Steven H. Strauss
doi:10.1038/nbt0505-532
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(65K)
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| Commentary |
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The Human Cancer Genome Project—one more misstep in the war on cancer pp535 - 537
George L Gabor Miklos
doi:10.1038/nbt0505-535
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(76K)
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| Investor's Lab |
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Beware the biotech barker p538
Tom Jacobs
doi:10.1038/nbt0505-538
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(37K)
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| Features | Top |
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Navigating an ethical patchwork—human gene banks pp539 - 545
Karen J Maschke
doi:10.1038/nbt0505-539
Abstract | Full text | PDF
(162K)
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| Patents |
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The challenge to patent law of pure chemical protein synthesis pp547 - 549
Aaron Xavier Fellmeth
doi:10.1038/nbt0505-547
Abstract | Full text | PDF
(104K)
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Patents p550
doi:10.1038/nbt0505-550
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(27K)
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| News and Views | Top |
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Therapeutic antibody gene transfer pp551 - 552
Wayne A Marasco
doi:10.1038/nbt0505-551
Abstract | Full text | PDF
(90K)
See also: Research by Fang et al. |
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Bringing amyloid into focus pp552 - 554
Todd E Golde
& Brian J Bacskai
doi:10.1038/nbt0505-552
Abstract | Full text | PDF
(109K)
See also: Research by Hintersteiner et al. |
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Reverse engineering gene regulatory networks pp554 - 555
Alexander J Hartemink
doi:10.1038/nbt0505-554
Abstract | Full text | PDF
(79K)
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Tunable antibodies pp556 - 557
Louis M Weiner
& Paul Carter
doi:10.1038/nbt0505-556
Abstract | Full text | PDF
(89K)
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Research Highlights p559
doi:10.1038/nbt0505-559
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(90K)
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| Computational Biology | Top |
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| Analysis |
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Systematic interpretation of genetic interactions using protein networks pp561 - 566
Ryan Kelley
& Trey Ideker
Published online: 05 May 2005 | doi:10.1038/nbt1096
Abstract | Full text | PDF
(595K)
| Supplementary Information |
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| Research | Top |
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| Review |
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Baculovirus as versatile vectors for protein expression in insect and mammalian cells pp567 - 575
Thomas A Kost, J Patrick Condreay
& Donald L Jarvis
Published online: 05 May 2005 | doi:10.1038/nbt1095
Abstract | Full text | PDF
(481K)
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| Articles |
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In vivo detection of amyloid- deposits by near-infrared imaging using an oxazine-derivative probe pp577 - 583
Martin Hintersteiner, Albert Enz, Peter Frey, Anne-Lise Jaton, Willy Kinzy, Rainer Kneuer, Ulf Neumann, Markus Rudin, Matthias Staufenbiel, Markus Stoeckli, Karl-Heinz Wiederhold
& Hans-Ulrich Gremlich
Published online: 17 April 2005 | doi:10.1038/nbt1085
Abstract | Full text | PDF
(552K)
See also: News and Views by Golde & Bacskai |
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Stable antibody expression at therapeutic levels using the 2A peptide pp584 - 590
Jianmin Fang, Jing-Jing Qian, Saili Yi, Thomas C Harding, Guang Huan Tu, Melinda VanRoey
& Karin Jooss
Published online: 17 April 2005 | doi:10.1038/nbt1087
Abstract | Full text | PDF
(342K)
See also: News and Views by Marasco |
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Gene knockdown by large circular antisense for high-throughput functional genomics pp591 - 599
Yun-Han Lee, Ik-Jae Moon, Bin Hur, Jeong-Hoh Park, Kil-Hwan Han, Seok-Yong Uhm, Yong-Joo Kim, Koo-Jeong Kang, Jong-Wook Park, Young-Bae Seu, Young-Ho Kim
& Jong-Gu Park
Published online: 01 May 2005 | doi:10.1038/nbt1089
Abstract | Full text | PDF
(458K)
| Supplementary Information |
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| Letters |
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Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain pp601 - 606
Viviane Tabar, Georgia Panagiotakos, Edward D Greenberg, Bill K Chan, Michel Sadelain, Philip H Gutin
& Lorenz Studer
Published online: 24 April 2005 | doi:10.1038/nbt1088
Abstract | Full text | PDF
(480K)
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Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells pp607 - 611
Shinsuke Yuasa, Yuji Itabashi, Uichi Koshimizu, Tomofumi Tanaka, Keijiro Sugimura, Masayoshi Kinoshita, Fumiyuki Hattori, Shin-ichi Fukami, Takuya Shimazaki, Hideyuki Okano, Satoshi Ogawa
& Keiichi Fukuda
Published online: 01 May 2005 | doi:10.1038/nbt1093
Abstract | Full text | PDF
(459K)
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Construction of lycopene-overproducing E. coli strains by combining systematic and combinatorial gene knockout targets pp612 - 616
Hal Alper, Kohei Miyaoku
& Gregory Stephanopoulos
Published online: 10 April 2005 | doi:10.1038/nbt1083
Abstract | Full text | PDF
(320K)
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Quantitative mouse brain proteomics using culture-derived isotope tags as internal standards pp617 - 621
Yasushi Ishihama, Toshitaka Sato, Tsuyoshi Tabata, Norimasa Miyamoto, Koji Sagane, Takeshi Nagasu
& Yoshiya Oda
Published online: 17 April 2005 | doi:10.1038/nbt1086
Abstract | Full text | PDF
(195K)
| Supplementary Information |
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Enzyme family−specific and activity-based screening of chemical libraries using enzyme microarrays pp622 - 627
Daniel P Funeriu, Jörg Eppinger, Lucile Denizot, Masato Miyake
& Jun Miyake
Published online: 10 April 2005 | doi:10.1038/nbt1090
Abstract | Full text | PDF
(674K)
| Supplementary Information |
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| Resources | Top |
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| New on the Market |
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Antibodies & Gene cloning p628
doi:10.1038/nbt0505-628
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(201K)
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| Naturejobs | Top |
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| Careers and Recruitment |
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US biotechnology companies and foreign nationals: the changing dynamics of access to H-1B visas pp629 - 630
A Stephen Dahms
& Stephen C Trow
doi:10.1038/nbt0505-629
Abstract | Full text | PDF
(42K)
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| People |
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People p632
doi:10.1038/nbt0505-632
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(68K)
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