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Tunable antibodies

A recent Keystone meeting highlighted the progress in generating effective anti-cancer antibodies by manipulating antibody binding affinity and their ability to support ADCC.

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Figure 1: Antibody structure can be manipulated to fit an intended therapeutic application.

Bob Crimi

References

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Weiner, L., Carter, P. Tunable antibodies. Nat Biotechnol 23, 556–557 (2005). https://doi.org/10.1038/nbt0505-556

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