 |
| In This Issue |  Top |
|
 |
|
| PDF |
|
| Editorial | Top |
|
|
|
The YIC factor p1187
doi:10.1038/nbt1005-1187
Full text | PDF
(71K)
|
|
| News | Top |
|
|
|
Korean biotechs seize opportunity to list on public markets pp1189 - 1190
Sabine Louët
Published online: 30 September 2005 | doi:10.1038/nbt1005-1189
Abstract | Full text | PDF
(197K)
|
|
|
|
Chiron's manufacturing misfortunes boost competitors p1191
Cormac Sheridan
Published online: 30 September 2005 | doi:10.1038/nbt1005-1191
Abstract | Full text | PDF
(101K)
|
|
|
|
New IGF drug stirs competition in growth factor segment p1192
Mark Ratner
Published online: 30 September 2005 | doi:10.1038/nbt1005-1192
Abstract | Full text | PDF
(144K)
|
|
|
|
Big biotech embraces direct-to-consumer advertising p1193
Alla Katsnelson
Published online: 30 September 2005 | doi:10.1038/nbt1005-1193
Abstract | Full text | PDF
(204K)
|
|
 |
|
| In Brief |
|
|
|
News In Brief pp1195 - 1196Published online: 30 September 2005 |
doi:10.1038/nbt1005-1195
Full text | PDF
(117K)
|
|
|
|
Profile: Jean Deleage p1197
Mark Ratner
Published online: 30 September 2005 | doi:10.1038/nbt1005-1197
Abstract | Full text | PDF
(74K)
|
|
|
|
| Data Page |
|
|
|
Biotech patenting slows in 2004 p1198
Stacy Lawrence
Published online: 30 September 2005 | doi:10.1038/nbt1005-1198
Full text | PDF
(127K)
|
|
|
|
| News Feature |
|
|
|
It came from beneath the sea pp1199 - 1201
Cormac Sheridan
Published online: 30 September 2005 | doi:10.1038/nbt1005-1199
Abstract | Full text | PDF
(170K)
|
|
| Bioentrepreneur | Top |
|
|
|
| Bioenews |
|
|
|
Looking at US versus European exit opportunities p1203
Stacy Lawrence
Published online: 12 August 2005 | doi:10.1038/bioent876
Reprinted with some modification from the Bioentrepreneur web portal (http://www.nature.com/bioent)
PDF
(115K)
|
|
|
|
| Building a business |
|
|
|
Virtual reality: the promise and pitfalls of going virtual pp1205 - 1207
Hal Broderson
Published online: 26 September 2005 | doi:10.1038/bioent881
Reprinted with some modification from the Bioentrepreneur web portal (http://www.nature.com/bioent)
PDF
(111K)
|
|
| Opinion and Comment | Top |
|
|
|
| Correspondence |
|
|
|
BIRB-796 is not an effective ABL(T315I) inhibitor pp1209 - 1210
Thomas O'Hare
& Brian J. Druker
doi:10.1038/nbt1005-1209
Full text | PDF
(137K)
|
|
|
|
Reply to BIRB-796 is not an effective ABL(T315I) inhibitor pp1210 - 1211
Miles A. Fabian, William H. Biggs III, Daniel K. Treiber, Patrick P. Zarrinkar
& David J. Lockhart
doi:10.1038/nbt1005-1210
Full text | PDF
(136K)
See also: Opinion and Comment by O'Hare & Druker |
|
|
|
Decentralization key to ScanBalt p1211
Peter Frank
doi:10.1038/nbt1005-1211
Full text | PDF
(120K)
|
|
|
|
NCRI Informatics Initiative p1212
Richard H.J. Begent, Peter Kerr, Helen Parkinson, Fiona Reddington
& J. Max Wilkinson
doi:10.1038/nbt1005-1212
Full text | PDF
(118K)
|
|
|
|
| Commentary |
|
|
|
A new role for scientists in the Biological Weapons Convention pp1213 - 1216
Gigi Kwik Grönvall
doi:10.1038/nbt1005-1213
Abstract | Full text | PDF
(124K)
|
|
|
|
Mind the (biomedical funding) gap pp1217 - 1218
Arthur Klausner
doi:10.1038/nbt1005-1217
Abstract | Full text | PDF
(113K)
|
|
|
|
| Investor's Lab |
|
|
|
A taxing dilemma p1219
Tom Jacobs
doi:10.1038/nbt1005-1219
Full text | PDF
(57K)
|
|
|
|
| Book Review |
|
|
|
Rejecting the gambler's principle p1220
Reviewed by: Daniel Callahan
doi:10.1038/nbt1005-1220
Full text | PDF
(82K)
|
|
| Features | Top |
|
|
|
A very firm handshake: biotech's growing negotiating power pp1221 - 1226
Karl A Thiel
doi:10.1038/nbt1005-1221
Abstract | Full text | PDF
(342K)
|
|
|
|
| Patents |
|
|
|
ESTs stumble at the utility threshold pp1227 - 1229
Paula K Davis, James J Kelley, Steven P Caltrider
& Stephen J Heinig
doi:10.1038/nbt1005-1227
Abstract | Full text | PDF
(90K)
|
|
|
|
Recent patent applications in imaging technology p1230
doi:10.1038/nbt1005-1230
Full text | PDF
(35K)
|
|
| News and Views | Top |
|
|
|
Islets for all? pp1231 - 1232
Hans E Hohmeier
& Christopher B Newgard
doi:10.1038/nbt1005-1231
Abstract | Full text | PDF
(138K)
See also: Research by Narushima et al. |
|
|
|
Antibodies in the breakdown lane pp1232 - 1234
Richard S Blumberg
& Wayne I Lencer
doi:10.1038/nbt1005-1232
Abstract | Full text | PDF
(220K)
See also: Research by Vaccaro et al. |
|
|
|
Simple recipe for blocking ion channels pp1234 - 1235
Christopher D Benham
doi:10.1038/nbt1005-1234
Abstract | Full text | PDF
(149K)
See also: Research by Xu et al. |
|
|
|
Bacteria to the rescue pp1236 - 1237
Rekha Seshadri
& John Heidelberg
doi:10.1038/nbt1005-1236
Abstract | Full text | PDF
(201K)
See also: Research by Kube et al. |
|
|
|
It takes a village to grow a tissue pp1237 - 1239
David L Kaplan, Randall T Moon
& Gordana Vunjak-Novakovic
doi:10.1038/nbt1005-1237
Abstract | Full text | PDF
(148K)
|
|
|
|
Research Highlights p1241
doi:10.1038/nbt1005-1241
Full text | PDF
(85K)
|
|
| Computational Biology | Top |
|
|
|
| Commentary |
|
|
|
Emergent behavior of growing knowledge about molecular interactions pp1243 - 1247
Murat Cokol, Ivan Iossifov, Chani Weinreb
& Andrey Rzhetsky
doi:10.1038/nbt1005-1243
Abstract | Full text | PDF
(681K)
| Supplementary Information |
|
|
|
| Analysis |
|
|
|
Discovery of regulatory elements in vertebrates through comparative genomics pp1249 - 1256
Amol Prakash
& Martin Tompa
Published online: 06 October 2005 | doi:10.1038/nbt1140
Abstract | Full text | PDF
(430K)
| Supplementary Information |
|
| Research | Top |
|
|
|
| Review |
|
|
|
Engineering novel binding proteins from nonimmunoglobulin domains pp1257 - 1268
H Kaspar Binz, Patrick Amstutz
& Andreas Plückthun
Published online: 06 October 2005 | doi:10.1038/nbt1127
Abstract | Full text | PDF
(627K)
| Supplementary Information |
|
|
|
| Articles |
|
|
|
Genome sequence of the chlorinated compound−respiring bacterium Dehalococcoides species strain CBDB1 pp1269 - 1273
Michael Kube, Alfred Beck, Stephen H Zinder, Heiner Kuhl, Richard Reinhardt
& Lorenz Adrian
Published online: 21 August 2005 | doi:10.1038/nbt1131
Abstract | Full text | PDF
(230K)
| Supplementary Information
See also: News and Views by Seshadri & Heidelberg |
|
|
|
A human  -cell line for transplantation therapy to control type 1 diabetes pp1274 - 1282
Michiki Narushima, Naoya Kobayashi, Teru Okitsu, Yoshihito Tanaka, Shun-Ai Li, Yong Chen, Atsushi Miki, Kimiaki Tanaka, Shuhei Nakaji, Kohji Takei, Alejandro Soto Gutierrez, Jorge David Rivas-Carrillo, Nalu Navarro-Álvarez, Hee-Sook Jun, Karen A Westerman, Hirofumi Noguchi, Jonathan R T Lakey, Philippe Leboulch, Noriaki Tanaka
& Ji-Won Yoon
Published online: 25 September 2005 | doi:10.1038/nbt1145
Abstract | Full text | PDF
(661K)
| Supplementary Information
See also: News and Views by Hohmeier & Newgard |
|
|
|
Engineering the Fc region of immunoglobulin G to modulate in vivo antibody levels pp1283 - 1288
Carlos Vaccaro, Jinchun Zhou, Raimund J Ober
& E Sally Ward
Published online: 25 September 2005 | doi:10.1038/nbt1143
Abstract | Full text | PDF
(290K)
| Supplementary Information
See also: News and Views by Blumberg & Lencer |
|
|
|
Generation of functional ion-channel tools by E3 targeting pp1289 - 1293
Shang-Zhong Xu, Fanning Zeng, Ming Lei, Jing Li, Bin Gao, Chenliang Xiong, Asipu Sivaprasadarao
& David J Beech
Published online: 18 September 2005 | doi:10.1038/nbt1148
Abstract | Full text | PDF
(437K)
See also: News and Views by Benham |
|
|
|
Multiplexed electrical detection of cancer markers with nanowire sensor arrays pp1294 - 1301
Gengfeng Zheng, Fernando Patolsky, Yi Cui, Wayne U Wang
& Charles M Lieber
Published online: 18 September 2005 | doi:10.1038/nbt1138
Abstract | Full text | PDF
(459K)
| Supplementary Information |
|
|
|
| Letters |
|
|
|
Target discovery in small-molecule cell-based screens by in situ proteome reactivity profiling pp1303 - 1307
Michael J Evans, Alan Saghatelian, Erik J Sorensen
& Benjamin F Cravatt
Published online: 02 October 2005 | doi:10.1038/nbt1149
Abstract | Full text | PDF
(275K)
| Supplementary Information |
|
|
|
Mammalian cell−based optimization of the biarsenical-binding tetracysteine motif for improved fluorescence and affinity pp1308 - 1314
Brent R Martin, Ben N G Giepmans, Stephen R Adams
& Roger Y Tsien
Published online: 11 September 2005 | doi:10.1038/nbt1136
Abstract | Full text | PDF
(498K)
| Supplementary Information |
|
| Corrigenda | Top |
|
|
|
Corrigendum: Design of a genome-wide siRNA library using an artificial neural network p1315
Dieter Huesken, Joerg Lange, Craig Mickanin, Jan Weiler, Fred Asselbergs, Justin Warner, Brian Meloon, Sharron Engel, Avi Rosenberg, Dalia Cohen, Mark Labow, Mischa Reinhardt, François Natt
& Jonathan Hall
doi:10.1038/nbt1005-1315a
Full text | PDF
(1,630K)
|
|
|
|
Corrigendum: Overexpression of an Arabidopsis thaliana ABC transporter confers kanamycin resistance to transgenic plants p1315
Ayalew Mentewab
& C Neal Stewart Jr
doi:10.1038/nbt1005-1315b
Full text | PDF
(326K)
|
|
| Erratum | Top |
|
|
|
Erratum: Chasing a cellular fountain of youth p1315
Ken Howard Wilan, Christopher Thomas Scott
& Stephan Herrera
doi:10.1038/nbt1005-1315c
Full text | PDF
(336K)
|
|
| Resources | Top |
|
|
|
| New on the Market |
|
|
|
Imaging & microscopy p1316
doi:10.1038/nbt1005-1316a
Full text | PDF
(171K)
|
|
|
|
Cell & tissue culture p1316
doi:10.1038/nbt1005-1316b
Full text | PDF
(171K)
|
|
| Naturejobs | Top |
|
|
|
| Careers and Recruitment |
|
|
|
An individual approach pp1317 - 1318
Ricki Lewis
doi:10.1038/nbt1005-1317
Abstract | Full text | PDF
(68K)
|
|
|
|
| People |
|
|
|
People p1320
doi:10.1038/nbt1005-1320
Full text | PDF
(83K)
|
|
|
Top |
|
|
