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| In This Issue |  Top |
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| Editorial | Top |
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Under surveillance p1
doi:10.1038/nbt0105-1
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(70K)
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| News | Top |
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Protein chip companies turn to biomarkers pp3 - 4
Cormac Sheridan
doi:10.1038/nbt0105-3
Abstract | Full text | PDF
(139K)
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Delisting threat looms large on biotech front p5
Stacy Lawrence
doi:10.1038/nbt0105-5
Abstract | Full text | PDF
(72K)
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Report recommends ban of US GM maize in Mexico p6
Jeffrey L. Fox
doi:10.1038/nbt0105-6
Abstract | Full text | PDF
(115K)
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UK seeks to relax shareholder preemption rights p7
Peter Vermij
doi:10.1038/nbt0105-7
Abstract | Full text | PDF
(121K)
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| In Brief |
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News In Brief pp9 - 10
doi:10.1038/nbt0105-9
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(107K)
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Profile: Kiran Mazumdar-Shaw p11
K.S. Jayaraman
doi:10.1038/nbt0105-11
Abstract | Full text | PDF
(81K)
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| Data Page |
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Tech transfer—slow progress p12
Stacy Lawrence
doi:10.1038/nbt0105-12
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(84K)
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| News Feature |
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International patent law—boon or bane of biotech? pp13 - 15
Paroma Basu
doi:10.1038/nbt0105-13
Abstract | Full text | PDF
(168K)
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| Opinion and Comment | Top |
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| Correspondence |
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BIO and biogenerics p17
Carl B. Feldbaum
doi:10.1038/nbt0105-17a
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(83K)
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Reply to 'BIO and biogenerics' p17
doi:10.1038/nbt0105-17b
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(83K)
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Good faith gone bad—gone good again p17
Harvey Bialy
doi:10.1038/nbt0105-17c
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(83K)
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Conditional alleles, inteins and degrons p18
Juraj Gregan
doi:10.1038/nbt0105-18a
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(68K)
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Biotech in post-TRIPS India pp18 - 19
Shyama V. Ramani, Preeti Pradhan
& Mahesh Ravi
doi:10.1038/nbt0105-18b
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(77K)
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Preserving the genetic integrity of human embryonic stem cells pp19 - 20
Maisam M. Mitalipova, Raj R. Rao, Deborah M. Hoyer, Julie A. Johnson, Lorraine F. Meisner, Karen L. Jones, Stephen Dalton
& Steven L. Stice
doi:10.1038/nbt0105-19
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(79K)
| Supplementary Information |
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| Commentary |
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Haplotyping in biomedicine—practical challenges pp21 - 22
Charles R Cantor
& Matthew R Nelson
doi:10.1038/nbt0105-21
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(105K)
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| Investor's Lab |
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Time to kick that drug habit p23
Tom Jacobs
doi:10.1038/nbt0105-23
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(57K)
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| Book Review |
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Living and dying with viruses p25
Reviewed by: Cormac Sheridan
doi:10.1038/nbt0105-25
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(86K)
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| Feature | Top |
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Poorer nations turn to publicly developed GM crops pp27 - 33
Joel I Cohen
doi:10.1038/nbt0105-27
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(295K)
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| News and Views | Top |
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Banking on red blood cells pp35 - 36
Narla Mohandas
doi:10.1038/nbt0105-35
Abstract | Full text | PDF
(124K)
See also: Research by Giarratana et al. |
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An enriched look at tyrosine phosphorylation pp36 - 37
Thomas P Conrads
& Timothy D Veenstra
doi:10.1038/nbt0105-36
Abstract | Full text | PDF
(118K)
See also: Research by Rush et al. |
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Sorting out metagenomes pp38 - 39
Jo Handelsman
doi:10.1038/nbt0105-38
Abstract | Full text | PDF
(142K)
See also: Research by Uchiyama et al. |
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Ethanol fermentation on the move pp40 - 41
Thomas W Jeffries
doi:10.1038/nbt0105-40
Abstract | Full text | PDF
(115K)
See also: Research by Seo et al. |
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Thiol modifications in a snapshot pp42 - 43
James Bardwell
doi:10.1038/nbt0105-42
Abstract | Full text | PDF
(109K)
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Research Highlights p45
doi:10.1038/nbt0105-45
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(73K)
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| Research | Top |
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| Review |
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Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering pp47 - 55
M P Lutolf
& J A Hubbell
Published online: 06 January 2005 | doi:10.1038/nbt1055
Abstract | Full text | PDF
(949K)
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| Perspective |
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Insect resistance management in GM crops: past, present and future pp57 - 62
Sarah L Bates, Jian-Zhou Zhao, Richard T Roush
& Anthony M Shelton
Published online: 06 January 2005 | doi:10.1038/nbt1056
Abstract | Full text | PDF
(207K)
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| Articles |
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The genome sequence of the ethanologenic bacterium Zymomonas mobilis ZM4 pp63 - 68
Jeong-Sun Seo, Hyonyong Chong, Hyun Seok Park, Kyoung-Oh Yoon, Cholhee Jung, Jae Joon Kim, Jin Han Hong, Hyungtae Kim, Jeong-Hyun Kim, Joon-Il Kil, Cheol Ju Park, Hyun-Myung Oh, Jung-Soon Lee, Su-Jung Jin, Hye-Won Um, Hee-Jong Lee, Soo-Jin Oh, Jae Young Kim, Hyung Lyun Kang, Se Yong Lee, Kye Joon Lee
& Hyen Sam Kang
Published online: 12 December 2004 | doi:10.1038/nbt1045
Abstract | Full text | PDF
(463K)
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See also: News and Views by Jeffries |
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Ex vivo generation of fully mature human red blood cells from hematopoietic stem cells pp69 - 74
Marie-Catherine Giarratana, Ladan Kobari, Hélène Lapillonne, David Chalmers, Laurent Kiger, Thérèse Cynober, Michael C Marden, Henri Wajcman
& Luc Douay
Published online: 26 December 2004 | doi:10.1038/nbt1047
Abstract | Full text | PDF
(501K)
See also: News and Views by Mohandas |
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A reverse genetic, nontransgenic approach to wheat crop improvement by TILLING pp75 - 81
Ann J Slade, Susan I Fuerstenberg, Dayna Loeffler, Michael N Steine
& Daniel Facciotti
Published online: 05 December 2004 | doi:10.1038/nbt1043
Abstract | Full text | PDF
(394K)
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| Letters |
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Microfluidic sorting of mammalian cells by optical force switching pp83 - 87
Mark M Wang, Eugene Tu, Daniel E Raymond, Joon Mo Yang, Haichuan Zhang, Norbert Hagen, Bob Dees, Elinore M Mercer, Anita H Forster, Ilona Kariv, Philippe J Marchand
& William F Butler
Published online: 19 December 2004 | doi:10.1038/nbt1050
Abstract | Full text | PDF
(341K)
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Substrate-induced gene-expression screening of environmental metagenome libraries for isolation of catabolic genes pp88 - 93
Taku Uchiyama, Takashi Abe, Toshimichi Ikemura
& Kazuya Watanabe
Published online: 19 December 2004 | doi:10.1038/nbt1048
Abstract | Full text | PDF
(187K)
See also: News and Views by Handelsman |
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Immunoaffinity profiling of tyrosine phosphorylation in cancer cells pp94 - 101
John Rush, Albrecht Moritz, Kimberly A Lee, Ailan Guo, Valerie L Goss, Erik J Spek, Hui Zhang, Xiang-Ming Zha, Roberto D Polakiewicz
& Michael J Comb
Published online: 12 December 2004 | doi:10.1038/nbt1046
Abstract | Full text | PDF
(345K)
| Supplementary Information
See also: News and Views by Conrads & Veenstra |
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Protein tagging and detection with engineered self-assembling fragments of green fluorescent protein pp102 - 107
Stéphanie Cabantous, Thomas C Terwilliger
& Geoffrey S Waldo
Published online: 05 December 2004 | doi:10.1038/nbt1044
Abstract | Full text | PDF
(333K)
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Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters pp108 - 116
Mario Amendola, Mary Anna Venneri, Alessandra Biffi, Elisa Vigna
& Luigi Naldini
Published online: 26 December 2004 | doi:10.1038/nbt1049
Abstract | Full text | PDF
(507K)
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| Errata |
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Erratum: Can China bring its own pipeline to the market? p117
Sabine Louët
doi:10.1038/nbt0105-117a
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(48K)
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Erratum: Agbio groups join BIO p117
Jeffrey L. Fox
doi:10.1038/nbt0105-117b
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(48K)
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| Corrigenda |
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Corrigenda: Antisense and siRNA as agonists of Toll-like receptors p117
Sudhir Agrawal
& Ekambar R Kandimalla
doi:10.1038/nbt0105-117c
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(48K)
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| Resources | Top |
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| Patents |
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Developing an intellectual property portfolio for the academic or not-for-profit institution pp119 - 121
Coe A Bloomberg
doi:10.1038/nbt0105-119
Abstract | Full text | PDF
(79K)
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Patents p123
doi:10.1038/nbt0105-123
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(37K)
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| People |
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People p125
doi:10.1038/nbt0105-125
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(65K)
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| New on the Market |
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Lab automation p127
doi:10.1038/nbt0105-127a
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(162K)
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Genomics & proteomics p127
doi:10.1038/nbt0105-127b
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(162K)
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| Quiz |
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The Nature Biotechnology 2005 New Year Quiz pp129 - 130
doi:10.1038/nbt0105-129
Full text | PDF
(77K)
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| Computational Biology | Top |
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| Perspective |
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Automatic generation of cellular reaction networks with Moleculizer 1.0 pp131 - 136
Larry Lok
& Roger Brent
Published online: 06 January 2005 | doi:10.1038/nbt1054
Abstract | Full text | PDF
(363K)
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| Analysis |
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Assessing computational tools for the discovery of transcription factor binding sites pp137 - 144
Martin Tompa, Nan Li, Timothy L Bailey, George M Church, Bart De Moor, Eleazar Eskin, Alexander V Favorov, Martin C Frith, Yutao Fu, W James Kent, Vsevolod J Makeev, Andrei A Mironov, William Stafford Noble, Giulio Pavesi, Graziano Pesole, Mireille Régnier, Nicolas Simonis, Saurabh Sinha, Gert Thijs, Jacques van Helden, Mathias Vandenbogaert, Zhiping Weng, Christopher Workman, Chun Ye
& Zhou Zhu
Published online: 06 January 2005 | doi:10.1038/nbt1053
Abstract | Full text | PDF
(198K)
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| Bioentrepreneur | Top |
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| Bioenews |
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Angel investors shy away from biotech p145
Aaron Bouchie
Published online: 18 November 2004 | doi:10.1038/bioent838
Reprinted with some modification from the Bioentrepreneur web portal (http://www.nature.com/bioent)
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(112K)
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| Building a business |
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Scaling the biobusiness information mountain pp147 - 149
Gwilym Williams
& Gary Walsh
Published online: 30 November 2004 | doi:10.1038/bioent836
Reprinted with some modification from the Bioentrepreneur web portal (http://www.nature.com/bioent)
PDF
(89K)
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| Naturejobs | Top |
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| Careers and Recruitment |
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Consider post-doctoral training in industry pp151 - 152
Grace H W Wong
doi:10.1038/nbt0105-151
Abstract | Full text | PDF
(66K)
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