 |
| In This Issue |  Top |
|
 |
|
| PDF |
|
| Editorial | Top |
|
|
|
Orphans at the window p1055
doi:10.1038/nbt0904-1055
Full text | PDF
(54K)
|
|
| News | Top |
|
|
|
Cash-strapped biotechs find financing alternative pp1057 - 1058
Peter Mitchell
Published online: 27 August 2004 | doi:10.1038/nbt0904-1057
Abstract | Full text | PDF
(94K)
|
|
|
|
As products enter clinic...scientists shown the door. p1059
Mark Ratner
Published online: 27 August 2004 | doi:10.1038/nbt0904-1059
Abstract | Full text | PDF
(76K)
|
|
|
|
Russia becomes attractive as a source of IP for biotechs p1060
Alla Katsnelson
Published online: 27 August 2004 | doi:10.1038/nbt0904-1060
Abstract | Full text | PDF
(232K)
|
|
|
|
EU to review rare disease drugs market exclusivity p1061
Cormac Sheridan
Published online: 27 August 2004 | doi:10.1038/nbt0904-1061
Abstract | Full text | PDF
(148K)
|
|
|
|
NAS issues mixed message on unintended effects of GM food p1062
Jeffrey L. Fox
Published online: 27 August 2004 | doi:10.1038/nbt0904-1062
Abstract | Full text | PDF
(315K)
|
|
|
|
France to focus on a few biotech clusters pp1063 - 1064
Emilie Balcon
Published online: 27 August 2004 | doi:10.1038/nbt0904-1063
Abstract | Full text | PDF
(209K)
|
|
 |
|
| In Brief |
|
|
|
News In Brief pp1065 - 1066Published online: 27 July 2004 |
doi:10.1038/nbt0904-1065
Full text | PDF
(146K)
|
|
|
|
Profile: Jim Greenwood p1067
Stephan Herrera
doi:10.1038/nbt0904-1067
Abstract | Full text | PDF
(129K)
|
|
|
|
| Data Page |
|
|
|
Biotech R&D still reeling p1068
Stacy Lawrence
doi:10.1038/nbt0904-1068
Full text | PDF
(51K)
|
|
|
|
| News Feature |
|
|
|
The faking of champions pp1069 - 1071
Laura DeFrancesco
Published online: 27 August 2004 | doi:10.1038/nbt0904-1069
Abstract | Full text | PDF
(460K)
|
|
|
|
Coming soon: a global grid for cancer research pp1071 - 1073
Aaron Bouchie
Published online: 27 August 2004 | doi:10.1038/nbt0904-1071
Abstract | Full text | PDF
(265K)
|
|
| Opinion and Comment | Top |
|
|
|
| Correspondence |
|
|
|
Developing market p1075
Wendy Taylor
doi:10.1038/nbt0904-1075
Full text | PDF
(134K)
|
|
|
|
The $802 million fallacy p1076
John Hodgson
doi:10.1038/nbt0904-1076a
Full text | PDF
(78K)
|
|
|
|
'Informative' horizontal gene transfer p1076
Harry J Gilbert, Anthony G O'Donnell
& John C Mathers
doi:10.1038/nbt0904-1076b
Full text | PDF
(78K)
|
|
|
|
Hydrocarbons and renewable energy p1077
Manfred Ringpfeil
doi:10.1038/nbt0904-1077a
Full text | PDF
(82K)
|
|
|
|
AIDS, aneuploidy and oncogenes p1077
Maxwell Gordon
doi:10.1038/nbt0904-1077b
Full text | PDF
(82K)
|
|
|
|
Reply to 'AIDS, aneuploidy and oncogenes' pp1077 - 1078
doi:10.1038/nbt0904-1077c
Full text | PDF
(117K)
|
|
|
|
Reply to 'AIDS, aneuploidy and oncogenes' p1078
doi:10.1038/nbt0904-1078a
Full text | PDF
(98K)
|
|
|
|
Genomic islands in Rhodopseudomonas palustris pp1078 - 1079
Chun-Ting Zhang
& Ren Zhang
doi:10.1038/nbt0904-1078b
Full text | PDF
(117K)
| Supplementary Information |
|
|
|
| Commentary |
|
|
|
Keeping dry and crossing membranes pp1081 - 1084
Ariel Fernández
doi:10.1038/nbt0904-1081
Full text | PDF
(184K)
|
|
|
|
| Investor's Lab |
|
|
|
Does biotech M&A benefit investors? p1085
Tom Jacobs
doi:10.1038/nbt0904-1085
Full text | PDF
(60K)
|
|
| Feature | Top |
|
|
|
Goodbye Columbus! New NRDOs forego discovery pp1087 - 1092
Karl A Thiel
doi:10.1038/nbt0904-1087
Abstract | Full text | PDF
(125K)
|
|
| News and Views | Top |
|
|
|
Phosphoproteomics finds its timing pp1093 - 1094
Sam A Johnson
& Tony Hunter
doi:10.1038/nbt0904-1093
Abstract | Full text | PDF
(205K)
See also: Research by Blagoev et al. |
|
|
|
 -cell precursors—a work in progress pp1095 - 1096
Gordon C Weir
& Susan Bonner-Weir
doi:10.1038/nbt0904-1095
Abstract | Full text | PDF
(177K)
See also: Research by Seaberg et al. |
|
|
|
Immunotherapy dispenses with tumor antigens pp1096 - 1098
Soldano Ferrone
doi:10.1038/nbt0904-1096
Abstract | Full text | PDF
(198K)
See also: Research by Daniels et al. |
|
|
|
Finding enzymatic gold on silver surfaces pp1098 - 1099
Uwe T Bornscheuer
doi:10.1038/nbt0904-1098
Abstract | Full text | PDF
(105K)
See also: Research by Moore et al. |
|
|
|
High-throughput biochemistry heats up pp1100 - 1101
F Raymond Salemme
doi:10.1038/nbt0904-1100
Abstract | Full text | PDF
(106K)
|
|
|
|
Research Highlights p1103
doi:10.1038/nbt0904-1103
Full text | PDF
(199K)
|
|
| Perspectives | Top |
|
|
|
Problems in monitoring horizontal gene transfer in field trials of transgenic plants pp1105 - 1109
Jack A Heinemann
& Terje Traavik
Published online: 31 August 2004 | doi:10.1038/nbt1009
Abstract | Full text | PDF
(183K)
|
|
|
|
Monitoring and modeling horizontal gene transfer pp1110 - 1114
Kaare M Nielsen
& Jeffrey P Townsend
Published online: 31 August 2004 | doi:10.1038/nbt1006
Abstract | Full text | PDF
(128K)
|
|
| Research | Top |
|
|
|
| Articles |
|
|
|
Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages pp1115 - 1124
Raewyn M Seaberg, Simon R Smukler, Timothy J Kieffer, Grigori Enikolopov, Zeenat Asghar, Michael B Wheeler, Gregory Korbutt
& Derek van der Kooy
Published online: 22 August 2004 | doi:10.1038/nbt1004
Abstract | Full text | PDF
(535K)
| Supplementary Information
See also: News and Views by Weir & Bonner-Weir |
|
|
|
A simple method to cure established tumors by inflammatory killing of normal cells pp1125 - 1132
Gregory A Daniels, Luis Sanchez-Perez, Rosa Maria Diaz, Timothy Kottke, Jill Thompson, Maoyi Lai, Michael Gough, Mahzuz Karim, Andrew Bushell, Heung Chong, Alan Melcher, Kevin Harrington
& Richard G Vile
Published online: 01 August 2004 | doi:10.1038/nbt1007
Abstract | Full text | PDF
(527K)
See also: News and Views by Ferrone |
|
|
|
Rapid and ultra-sensitive determination of enzyme activities using surface-enhanced resonance Raman scattering pp1133 - 1138
Barry D Moore, Lorna Stevenson, Alan Watt, Sabine Flitsch, Nicolas J Turner, Chris Cassidy
& Duncan Graham
Published online: 08 August 2004 | doi:10.1038/nbt1003
Abstract | Full text | PDF
(268K)
| Supplementary Information
See also: News and Views by Bornscheuer |
|
|
|
| Letters |
|
|
|
Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics pp1139 - 1145
Blagoy Blagoev, Shao-En Ong, Irina Kratchmarova
& Matthias Mann
Published online: 15 August 2004 | doi:10.1038/nbt1005
Abstract | Full text | PDF
(320K)
| Supplementary Information
See also: News and Views by Johnson & Hunter |
|
|
|
5'-end SAGE for the analysis of transcriptional start sites pp1146 - 1149
Shin-ichi Hashimoto, Yutaka Suzuki, Yasuhiro Kasai, Kei Morohoshi, Tomoyuki Yamada, Jun Sese, Shinichi Morishita, Sumio Sugano
& Kouji Matsushima
Published online: 08 August 2004 | doi:10.1038/nbt998
Abstract | Full text | PDF
(220K)
| Supplementary Information |
|
|
|
Post-integration stabilization of a transposon vector by terminal sequence deletion in Drosophila melanogaster pp1150 - 1154
Alfred M Handler, Grazyna J Zimowska
& Carsten Horn
Published online: 08 August 2004 | doi:10.1038/nbt1002
Abstract | Full text | PDF
(230K)
|
|
|
|
Evolution of a T7 RNA polymerase variant that transcribes 2'-O-methyl RNA pp1155 - 1160
Jijumon Chelliserrykattil
& Andrew D Ellington
Published online: 08 August 2004 | doi:10.1038/nbt1001
Abstract | Full text | PDF
(292K)
|
|
|
|
Aggregation-resistant domain antibodies selected on phage by heat denaturation pp1161 - 1165
Laurent Jespers, Oliver Schon, Kristoffer Famm
& Greg Winter
Published online: 08 August 2004 | doi:10.1038/nbt1000
Abstract | Full text | PDF
(360K)
|
|
| Resources | Top |
|
|
|
| Patents |
|
|
|
The exclusion of diagnostic methods from patentability by the EPC: a case for review? pp1167 - 1168
Mathias Ricker
doi:10.1038/nbt0904-1167
Abstract | Full text | PDF
(64K)
|
|
|
|
New Patents p1169
doi:10.1038/nbt0904-1169
Full text | PDF
(32K)
|
|
|
|
| People |
|
|
|
People p1171
doi:10.1038/nbt0904-1171
Full text | PDF
(68K)
|
|
|
|
| New on the Market |
|
|
|
Software & Liquid handling pp1173 - 1175
doi:10.1038/nbt0904-1173
Full text | PDF
(283K)
|
|
| Computational Biology | Top |
|
|
|
| Primer |
|
|
|
What is Bayesian statistics? pp1177 - 1178
Sean R Eddy
doi:10.1038/nbt0904-1177
Abstract | Full text | PDF
(91K)
|
|
|
|
| Commentary |
|
|
|
Funding high-throughput data sharing pp1179 - 1183
Catherine A Ball, Gavin Sherlock
& Alvis Brazma
doi:10.1038/nbt0904-1179
Full text | PDF
(109K)
|
|
| Bioentrepreneur | Top |
|
|
|
| Bioenews |
|
|
|
Napster case spills into biotech sector pp1185 - 1186
Aaron Bouchie
Published online: 29 July 2004 | doi:10.1038/bioent822
Reprinted with some modification from the Bioentrepreneur web portal (http://www.nature.com/bioent)
PDF
(297K)
|
|
|
|
| Building a business |
|
|
|
Riding the risk cycle pp1187 - 1188
Roop Chandwani
& Simon Portman
Published online: 26 July 2004 | doi:10.1038/bioent817
Reprinted with some modification from the Bioentrepreneur web portal (http://www.nature.com/bioent)
PDF
(69K)
|
|
| Naturejobs | Top |
|
|
|
| Careers and Recruitment |
|
|
|
Strategic HR for today's biotechnology companies p1189
Mary Yaroshevsky-Glanville
doi:10.1038/nbt0904-1189
Abstract | Full text | PDF
(59K)
|
|
|
Top |
|
|
