Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Editing the message from A to I

Numerous adenosine-to-inosine editing sites found in mRNA sequences raise new questions about the biological significance of RNA editing.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Processes possibly affected by A-to-I RNA editing of non-coding repetitive sequences.

Bob Crimi

References

  1. Maas, S., Rich, A. & Nishikura, K. J. Biol. Chem. 278, 1391–1394 (2003).

    Article  CAS  Google Scholar 

  2. Paul, M.S. & Bass, B.L. EMBO J. 17, 1120–1127 (1998).

    Article  CAS  Google Scholar 

  3. Levanon, E.Y. et al. Nat. Biotechnol. 22, 1001–1005 (2004).

    Article  CAS  Google Scholar 

  4. Kikuno, R., Nagase, T., Waki, M. & Ohara, O. Nucleic Acids Res. 30, 166–168 (2002).

    Article  CAS  Google Scholar 

  5. Hoopengardner, B., Bhalla, T., Staber, C. & Reenan, R. Science 301, 832–836 (2003).

    Article  CAS  Google Scholar 

  6. Morse, D.P., Aruscavage, P.J. & Bass, B.L. Proc. Natl. Acad. Sci. USA 99, 7906–7911 (2002).

    Article  CAS  Google Scholar 

  7. Reenan, R.A., Hanrahan, C.J. & Ganetzky, B. Neuron 25, 139–149 (2000).

    Article  CAS  Google Scholar 

  8. Schramke, V. & Allshire, R. Science 301, 1069–1074 (2003).

    Article  CAS  Google Scholar 

  9. Han, J.S., Szak, S.T. & Boeke, J.D. Nature 429, 268–318 (2004).

    Article  CAS  Google Scholar 

  10. Knight, S.W. & Bass, B.L. Mol. Cell 10, 809–817 (2002).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nishikura, K. Editing the message from A to I. Nat Biotechnol 22, 962–963 (2004). https://doi.org/10.1038/nbt0804-962

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nbt0804-962

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing