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Volume 22 Issue 5, May 2004

A root of a poplar colonized by the green fluorescent protein-labeled endophytic bacterium Pseudomonas putida VM1453. Photo courtesy of Kieran Germaine, David Ryan and David Dowling Department of Applied Biology & Chemistry, Institute of Technology, Carlow, Ireland). On page 583, van der Lelie and colleagues describe a yellow lupin containing a modified endophytic symbiont capable of toluene degradation.

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  • Will formal entry into the European Union enable the eight new Central European members to galvanize their biotech sectors? Clare Sansom reports.

    • Clare Sansom
    News Feature
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Correspondence

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Investors Lab

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  • Has structural bioinformatics advanced enough to form the core of a drug discovery program? A new generation of companies exploiting structure-focused technologies is counting on it.

    • Karl A Thiel
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News & Views

  • Ankyrin repeats generate high-affinity protein binders with biophysical properties that may favor therapeutic applications.

    • Ian M Tomlinson
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  • Chemical screening in a zebrafish mutant has turned up two compounds that rescue a heart defect, but will this yield new drugs?

    • Jonathan Margolis
    • Greg D Plowman
    News & Views
  • The genome sequence of Thermus thermophilus may provide new insights into heat-tolerant enzymes and metabolic pathways of biotechnological potential.

    • Wolfgang Liebl
    News & Views
  • Genetically modified (GM) bacteria improve the degradation of toluene in plants.

    • Bernard R Glick
    News & Views
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News and Views Feature

  • The complete genome sequence of the rat provides new signposts on the road to functional determination in higher eukaryotes.

    • Ismail Kola
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Patents

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People

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