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Nature Biotechnology
ISSUE
February 2004, Volume 22 No 2
In This Issue
Editorial
NewsIn Brief | News Feature
Opinion and CommentCorrespondence | Commentary | Book Review
Feature
News and Views
ResearchPerspective | Articles | Letters
ResourcesPatents | People | New on the Market
BioentrepreneurBioenews | Building a business
NaturejobsCareers and Recruitment
About the cover
In This Issue Top
PDF
Editorial Top
Drugs in crops—the unpalatable truth p133
doi:10.1038/nbt0204-133
Full text | PDF (97K)
News Top
Biotech holds steady in Q4 pp135 - 136
Peter Mitchell
doi:10.1038/nbt0204-135
Full text | PDF (278K)
China pushes liver proteomics p136
Hepeng Jia & Sabine Louët
doi:10.1038/nbt0204-136
Full text | PDF (252K)
Genomics companies shop around for chemical expertise pp137 - 138
Liz Fletcher
doi:10.1038/nbt0204-137
Full text | PDF (242K)
Rogan steps down as USPTO director p139
Aparna Surendran
doi:10.1038/nbt0204-139
Full text | PDF (209K)
In Brief
News In Brief pp141 - 143
doi:10.1038/nbt0204-141
Full text | PDF (212K)
News Feature
Make or break for costimulatory blockers pp145 - 147
Ken Garber
doi:10.1038/nbt0204-145
Abstract | Full text | PDF (303K)
Opinion and Comment Top
Correspondence
Questions linger over European GM food regulations p149
Daniel Ramón, Andrew MacCabe & José Vicente Gil
doi:10.1038/nbt0204-149
Full text | PDF (189K)
Commentary
Beyond the Petri dish pp151 - 152
Shuguang Zhang
doi:10.1038/nbt0204-151
Full text | PDF (320K)
The prevalence of patent interferences in gene technology pp153 - 154
Jon F Merz & Michelle R Henry
doi:10.1038/nbt0204-153
Full text | PDF (90K)
Book Review
Journalism with a worldview pp155 - 156
Reviewed by: Matthew C Nisbet
doi:10.1038/nbt0204-155
Full text | PDF (113K)
Feature Top
A regulatory patchwork—human ES cell research oversight pp157 - 163
Lori P Knowles
doi:10.1038/nbt0204-157
Abstract | Full text | PDF (1,372K)
News and Views Top
Breaching the skin's barrier to drugs pp165 - 167
Brian W Barry
doi:10.1038/nbt0204-165
Abstract | Full text | PDF (330K)
See also: Research by Karande et al.
Phage-inspired antibiotics? pp167 - 168
Steven Projan
doi:10.1038/nbt0204-167
Abstract | Full text | PDF (199K)
See also: Research by Liu et al.
Enlightened receptor dynamics pp169 - 170
Gal Gur & Yosef Yarden
doi:10.1038/nbt0204-169
Abstract | Full text | PDF (362K)
See also: Research by Lidke et al.
The fate of transgenes in the human gut pp170 - 172
John Heritage
doi:10.1038/nbt0204-170
Abstract | Full text | PDF (624K)
See also: Research by Netherwood et al.
Label-free detection becomes crystal clear pp172 - 173
Paul S Cremer
doi:10.1038/nbt0204-172
Abstract | Full text | PDF (143K)
Research notes p175
doi:10.1038/nbt0204-175
Full text | PDF (175K)
Research Top
Perspective
The HUPO PSI's Molecular Interaction format—a community standard for the representation of protein interaction data pp177 - 183
Henning Hermjakob, Luisa Montecchi-Palazzi, Gary Bader, Jérôme Wojcik, Lukasz Salwinski, Arnaud Ceol, Susan Moore, Sandra Orchard, Ugis Sarkans, Christian von Mering, Bernd Roechert, Sylvain Poux, Eva Jung, Henning Mersch, Paul Kersey, Michael Lappe, Yixue Li, Rong Zeng, Debashis Rana, Macha Nikolski, Holger Husi, Christine Brun, K Shanker, Seth G N Grant, Chris Sander, Peer Bork, Weimin Zhu, Akhilesh Pandey, Alvis Brazma, Bernard Jacq, Marc Vidal, David Sherman, Pierre Legrain, Gianni Cesareni, Ioannis Xenarios, David Eisenberg, Boris Steipe, Chris Hogue & Rolf Apweiler
Published online: 30 January 2004 | doi:10.1038/nbt926
Abstract | Full text | PDF (1,518K)
Articles
Antimicrobial drug discovery through bacteriophage genomics pp185 - 191
Jing Liu, Mohammed Dehbi, Greg Moeck, Francis Arhin, Pascale Bauda, Dominique Bergeron, Mario Callejo, Vincent Ferretti, Nhuan Ha, Tony Kwan, John McCarty, Ramakrishnan Srikumar, Dan Williams, Jinzi J Wu, Philippe Gros, Jerry Pelletier & Michael DuBow
Published online: 11 January 2004 | doi:10.1038/nbt932
Abstract | Full text | PDF (652K)
See also: News and Views by Projan
Discovery of transdermal penetration enhancers by high-throughput screening pp192 - 197
Pankaj Karande, Amit Jain & Samir Mitragotri
Published online: 04 January 2004 | doi:10.1038/nbt928
Abstract | Full text | PDF (731K)
See also: News and Views by Barry
Quantum dot ligands provide new insights into erbB/HER receptor−mediated signal transduction pp198 - 203
Diane S Lidke, Peter Nagy, Rainer Heintzmann, Donna J Arndt-Jovin, Janine N Post, Hernan E Grecco, Elizabeth A Jares-Erijman & Thomas M Jovin
Published online: 04 January 2004 | doi:10.1038/nbt929
Abstract | Full text | PDF (1,881K)  | Supplementary Information
See also: News and Views by Gur & Yarden
Assessing the survival of transgenic plant DNA in the human gastrointestinal tract pp204 - 209
Trudy Netherwood, Susana M Martín-Orúe, Anthony G O'Donnell, Sally Gockling, Julia Graham, John C Mathers & Harry J Gilbert
Published online: 18 January 2004 | doi:10.1038/nbt934
Abstract | Full text | PDF (435K)
See also: News and Views by Heritage
Letters
Enzyme immobilization in a biomimetic silica support pp211 - 213
Heather R Luckarift, Jim C Spain, Rajesh R Naik & Morley O Stone
Published online: 11 January 2004 | doi:10.1038/nbt931
Abstract | Full text | PDF (203K)
Intensity-based protein identification by machine learning from a library of tandem mass spectra pp214 - 219
Joshua E Elias, Francis D Gibbons, Oliver D King, Frederick P Roth & Steven P Gygi
Published online: 18 January 2004 | doi:10.1038/nbt930
Abstract | Full text | PDF (282K)  | Supplementary Information
FRET between cardiac Na+ channel subunits measured with a confocal microscope and a streak camera pp220 - 224
Christoph Biskup, Thomas Zimmer & Klaus Benndorf
Published online: 18 January 2004 | doi:10.1038/nbt935
Abstract | Full text | PDF (678K)  | Supplementary Information
Generation of marker-free plastid transformants using a transiently cointegrated selection gene pp225 - 229
Sebastian M J Klaus, Fong-Chin Huang, Timothy J Golds & Hans-Ulrich Koop
Published online: 18 January 2004 | doi:10.1038/nbt933
Abstract | Full text | PDF (737K)
Resources Top
Patents
Genetic sequences: how are they patented? pp231 - 232
Guillaume Dufresne & Manuel Duval
doi:10.1038/nbt0204-231
Abstract | Full text | PDF (66K)
Recent patent applications in tissue engineering p233
doi:10.1038/nbt0204-233
Full text | PDF (35K)
People
People p235
doi:10.1038/nbt0204-235
Full text | PDF (55K)
New on the Market
Microarrays and Reagents & enzymes p237
doi:10.1038/nbt0204-237
Full text | PDF (266K)
Bioentrepreneur Top
Bioenews
Biotechs critique big pharma's collaboration skills pp239 - 240
Emma Dorey
Published online: 18 December 2003 | doi:10.1038/bioent787
Three US states launch biotech seed funds pp240 - 241
Ken Howard
Published online: 31 December 2003 | doi:10.1038/bioent788
UK urged to plug "bioprocessing gap" pp241 - 242
Peter Mitchell
Published online: 11 December 2003 | doi:10.1038/bioent786
Arizona's sales tax diverted to biotech research pp242 - 243
Aparna Surendran
Published online: 08 January 2004 | doi:10.1038/bioent790
Reprinted with some modification from the Bioentrepreneur web portal (http://www.nature.com/bioent)

PDF (376K)
Building a business
Term sheet trends in the venture capital market pp243 - 245
Luci Staller Altman
Published online: 22 December 2003 | doi:10.1038/bioent785
Reprinted with some modification from the Bioentrepreneur web portal (http://www.nature.com/bioent)

PDF (85K)
Naturejobs Top
Careers and Recruitment
Graduate education and employment opportunities in bioethics pp247 - 249
Leigh Turner
doi:10.1038/nbt0204-247
Abstract | Full text | PDF (71K)
  Top
 
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ISSN: 1087-0156
EISSN: 1546-1696
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