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Nature Biotechnology
ISSUE
January 2004, Volume 22 No 1
In This Issue
Editorial
NewsIn Brief | News Feature
Opinion and CommentCorrespondence | Commentary | Fool's Corner | Book Review
Feature
News and Views
ResearchPerspective | Brief Communications | Articles | Letters
ResourcesPatents | People | New on the Market | Quiz
BioentrepreneurBioenews | Building a business
NaturejobsCareers and Recruitment
About the cover
In This Issue Top
PDF
Editorial Top
The one that got away p1
doi:10.1038/nbt0104-1
Full text | PDF (53K)
News Top
China approves first gene therapy pp3 - 4
Sue Pearson, Hepeng Jia & Keiko Kandachi
doi:10.1038/nbt0104-3
Full text | PDF (370K)
Vatican debates agbiotech pp4 - 5
Jeffrey L. Fox
doi:10.1038/nbt0104-4
Full text | PDF (285K)
UK to pursue contract clinical trials pp5 - 6
Sabine Louët
doi:10.1038/nbt0104-5
Full text | PDF (156K)
Cancer trials get set for biomarkers pp6 - 7
Aaron Bouchie
doi:10.1038/nbt0104-6
Full text | PDF (460K)
Chile launches policy to boost biotech pp7 - 8
Claudia Orellana
doi:10.1038/nbt0104-7
Full text | PDF (460K)
Nasdaq dilutes its biotech index p9
Emma Dorey
doi:10.1038/nbt0104-9
Full text | PDF (58K)
In Brief
News In Brief pp11 - 13
doi:10.1038/nbt0104-11
Full text | PDF (195K)
News Feature
Signal transduction inhibitors—a work in progress pp15 - 18
Joseph Becker
doi:10.1038/nbt0104-15
Abstract | Full text | PDF (257K)
Opinion and Comment Top
Correspondence
Health impact of nanomaterials? p19
Peter H M Hoet, Abderrahim Nemmar & Benoit Nemery
doi:10.1038/nbt0104-19
Full text | PDF (63K)
Realities for Latin American and Caribbean biotech p20
Rafael Rangel-Aldao
doi:10.1038/nbt0104-20
Full text | PDF (60K)
Commentary
The emerging role of academia in commercializing innovation pp21 - 24
Shreefal Mehta
doi:10.1038/nbt0104-21
Full text | PDF (112K)
Do cloned mammals skip a reprogramming step? pp25 - 26
Josef Fulka Jr., Norikazu Miyashita, Takashi Nagai & Atsuo Ogura
doi:10.1038/nbt0104-25
Full text | PDF (123K)
Fool's Corner
How do your stocks really perform? p27
Tom Jacobs
doi:10.1038/nbt0104-27
Full text | PDF (64K)
Book Review
Hybrids abounding pp29 - 30
Reviewed by: Steven H Strauss & Stephen P DiFazio
doi:10.1038/nbt0104-29
Full text | PDF (118K)
Feature Top
Old dogma, new tricks—21st Century phage therapy pp31 - 36
Karl Thiel
doi:10.1038/nbt0104-31
Abstract | Full text | PDF (1,825K)
News and Views Top
The biological magic behind the bullets pp37 - 38
Brent R Stockwell
doi:10.1038/nbt0104-37
Abstract | Full text | PDF (103K)
See also: Research by Parsons et al.
Cancer surgery joins the dots pp38 - 39
Roger F Uren
doi:10.1038/nbt0104-38
Abstract | Full text | PDF (196K)
See also: Research by Kim et al.
Rain or shine—a phototroph that delivers pp40 - 41
Judy D Wall
doi:10.1038/nbt0104-40
Abstract | Full text | PDF (370K)
See also: Research by Larimer et al.
Unnatural selection of cultured human ES cells? pp42 - 43
Martin F Pera
doi:10.1038/nbt0104-42
Abstract | Full text | PDF (148K)
See also: Research by Draper et al.
Protein interaction maps on the fly pp43 - 44
Peter Uetz & Michael J Pankratz
doi:10.1038/nbt0104-43
Abstract | Full text | PDF (378K)
See also: Research by Bader et al.
Research notes p45
doi:10.1038/nbt0104-45
Full text | PDF (105K)
Research Top
Perspective
The use of nanocrystals in biological detection pp47 - 52
Paul Alivisatos
Published online: 02 January 2003 | doi:10.1038/nbt927
Abstract | Full text | PDF (1,053K)
Brief Communications
Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells pp53 - 54
Jonathan S Draper, Kath Smith, Paul Gokhale, Harry D Moore, Edna Maltby, Julie Johnson, Lorraine Meisner, Thomas P Zwaka, James A Thomson & Peter W Andrews
Published online: 07 December 2003 | doi:10.1038/nbt922
Abstract | Full text | PDF (100K)  | Supplementary Information
See also: News and Views by Pera
Articles
Complete genome sequence of the metabolically versatile photosynthetic bacterium Rhodopseudomonas palustris pp55 - 61
Frank W Larimer, Patrick Chain, Loren Hauser, Jane Lamerdin, Stephanie Malfatti, Long Do, Miriam L Land, Dale A Pelletier, J Thomas Beatty, Andrew S Lang, F Robert Tabita, Janet L Gibson, Thomas E Hanson, Cedric Bobst, Janelle L Torres y Torres, Caroline Peres, Faith H Harrison, Jane Gibson & Caroline S Harwood
Published online: 14 December 2003 | doi:10.1038/nbt923
Abstract | Full text | PDF (386K)  | Supplementary Information
See also: News and Views by Wall
Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways pp62 - 69
Ainslie B Parsons, Renée L Brost, Huiming Ding, Zhijian Li, Chaoying Zhang, Bilal Sheikh, Grant W Brown, Patricia M Kane, Timothy R Hughes & Charles Boone
Published online: 07 December 2003 | doi:10.1038/nbt919
Abstract | Full text | PDF (218K)  | Supplementary Information
See also: News and Views by Stockwell
Systemic tumor targeting and killing by Sindbis viral vectors pp70 - 77
Jen-Chieh Tseng, Brandi Levin, Alicia Hurtado, Herman Yee, Ignacio Perez de Castro, Maria Jimenez, Peter Shamamian, Ruzhong Jin, Richard P Novick, Angel Pellicer & Daniel Meruelo
Published online: 30 November 2003 | doi:10.1038/nbt917
Abstract | Full text | PDF (1,800K)
Gaining confidence in high-throughput protein interaction networks pp78 - 85
Joel S Bader, Amitabha Chaudhuri, Jonathan M Rothberg & John Chant
Published online: 14 December 2003 | doi:10.1038/nbt924
Abstract | Full text | PDF (275K)  | Supplementary Information
See also: News and Views by Uetz & Pankratz
Principles of transcriptional control in the metabolic network of Saccharomyces cerevisiae pp86 - 92
Jan Ihmels, Ronen Levy & Naama Barkai
Published online: 30 November 2003 | doi:10.1038/nbt918
Abstract | Full text | PDF (157K)  | Supplementary Information
Letters
Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping pp93 - 97
Sungjee Kim, Yong Taik Lim, Edward G Soltesz, Alec M De Grand, Jaihyoung Lee, Akira Nakayama, J Anthony Parker, Tomislav Mihaljevic, Rita G Laurence, Delphine M Dor, Lawrence H Cohn, Moungi G Bawendi & John V Frangioni
Published online: 07 December 2003 | doi:10.1038/nbt920
Abstract | Full text | PDF (1,751K)  | Supplementary Information
See also: News and Views by Uren
Unraveling protein interaction networks with near-optimal efficiency pp98 - 103
Michael Lappe & Liisa Holm
Published online: 07 December 2003 | doi:10.1038/nbt921
Abstract | Full text | PDF (302K)  | Supplementary Information
Systematic identification of sense-antisense transcripts in mammalian cells pp104 - 108
Øystein Røsok & Mouldy Sioud
Published online: 14 December 2003 | doi:10.1038/nbt925
Abstract | Full text | PDF (291K)  | Supplementary Information
Resources Top
Patents
Patent protection for protein structure analysis pp109 - 112
Itsuki Shimbo, Rie Nakajima, Shigeyuki Yokoyama & Koichi Sumikura
doi:10.1038/nbt0104-109
Abstract | Full text | PDF (96K)
Recent patent applications in proteomics p113
doi:10.1038/nbt0104-113
Full text | PDF (31K)
People
People pp115 - 117
doi:10.1038/nbt0104-115
Full text | PDF (116K)
New on the Market
Lab automation & Proteomics p119
doi:10.1038/nbt0104-119
Full text | PDF (255K)
Quiz
The Nature Biotechnology 2004 New Year Quiz pp121 - 122
doi:10.1038/nbt0104-121
Full text | PDF (82K)
Bioentrepreneur Top
Bioenews
Humboldt University beefs up technology transfer pp123 - 124
Martina Habeck
Published online: 13 November 2003 | doi:10.1038/bioent781
Scripps lured to Sunshine State pp124 - 125
Aaron Bouchie
Published online: 20 November 2003 | doi:10.1038/bioent782
France critiques its incubators before refinancing p126
Sabine Louët
Published online: 04 December 2003 | doi:10.1038/bioent784
Reprinted with some modification from the Bioentrepreneur web portal (http://www.nature.com/bioent)

PDF (346K)
Building a business
Proactive accounting: a key factor in the success of biotechnology startups pp127 - 129
Christian C. Jester
Published online: 24 November 2003 | doi:10.1038/bioent779
Reprinted with some modification from the Bioentrepreneur web portal (http://www.nature.com/bioent)

PDF (76K)
Naturejobs Top
Careers and Recruitment
Does your chairman need to be Superman? pp131 - 132
Nicolas Hollanders
doi:10.1038/nbt0104-131
Abstract | Full text | PDF (77K)
  Top
 
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Nature Biotechnology
ISSN: 1087-0156
EISSN: 1546-1696
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