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| In This Issue | Top |
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| Editorial | Top |
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The one that got away p1 doi:10.1038/nbt0104-1 Full text | PDF
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| News | Top |
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China approves first gene therapy pp3 - 4 Sue Pearson, Hepeng Jia
& Keiko Kandachi doi:10.1038/nbt0104-3 Full text | PDF
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Vatican debates agbiotech pp4 - 5 Jeffrey L. Fox doi:10.1038/nbt0104-4 Full text | PDF
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UK to pursue contract clinical trials pp5 - 6 Sabine Louët doi:10.1038/nbt0104-5 Full text | PDF
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Cancer trials get set for biomarkers pp6 - 7 Aaron Bouchie doi:10.1038/nbt0104-6 Full text | PDF
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Chile launches policy to boost biotech pp7 - 8 Claudia Orellana doi:10.1038/nbt0104-7 Full text | PDF
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Nasdaq dilutes its biotech index p9 Emma Dorey doi:10.1038/nbt0104-9 Full text | PDF
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| In Brief |
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News In Brief pp11 - 13 doi:10.1038/nbt0104-11 Full text | PDF
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| News Feature |
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Signal transduction inhibitorsa work in progress pp15 - 18 Joseph Becker doi:10.1038/nbt0104-15 Abstract | Full text | PDF
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| Opinion and Comment | Top |
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| Correspondence |
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Health impact of nanomaterials? p19 Peter H M Hoet, Abderrahim Nemmar
& Benoit Nemery doi:10.1038/nbt0104-19 Full text | PDF
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Realities for Latin American and Caribbean biotech p20 Rafael Rangel-Aldao doi:10.1038/nbt0104-20 Full text | PDF
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| Commentary |
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The emerging role of academia in commercializing innovation pp21 - 24 Shreefal Mehta doi:10.1038/nbt0104-21 Full text | PDF
(112K)
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Do cloned mammals skip a reprogramming step? pp25 - 26 Josef Fulka Jr., Norikazu Miyashita, Takashi Nagai
& Atsuo Ogura doi:10.1038/nbt0104-25 Full text | PDF
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| Fool's Corner |
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How do your stocks really perform? p27 Tom Jacobs doi:10.1038/nbt0104-27 Full text | PDF
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| Book Review |
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Hybrids abounding pp29 - 30 Reviewed by: Steven H Strauss
& Stephen P DiFazio doi:10.1038/nbt0104-29 Full text | PDF
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| Feature | Top |
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Old dogma, new tricks21st Century phage therapy pp31 - 36 Karl Thiel doi:10.1038/nbt0104-31 Abstract | Full text | PDF
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| News and Views | Top |
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The biological magic behind the bullets pp37 - 38 Brent R Stockwell doi:10.1038/nbt0104-37 Abstract | Full text | PDF
(103K)
See also: Research by Parsons et al. |
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Cancer surgery joins the dots pp38 - 39 Roger F Uren doi:10.1038/nbt0104-38 Abstract | Full text | PDF
(196K)
See also: Research by Kim et al. |
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Rain or shinea phototroph that delivers pp40 - 41 Judy D Wall doi:10.1038/nbt0104-40 Abstract | Full text | PDF
(370K)
See also: Research by Larimer et al. |
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Unnatural selection of cultured human ES cells? pp42 - 43 Martin F Pera doi:10.1038/nbt0104-42 Abstract | Full text | PDF
(148K)
See also: Research by Draper et al. |
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Protein interaction maps on the fly pp43 - 44 Peter Uetz
& Michael J Pankratz doi:10.1038/nbt0104-43 Abstract | Full text | PDF
(378K)
See also: Research by Bader et al. |
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Research notes p45 doi:10.1038/nbt0104-45 Full text | PDF
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| Research | Top |
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| Perspective |
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The use of nanocrystals in biological detection pp47 - 52 Paul Alivisatos Published online: 02 January 2003 | doi:10.1038/nbt927 Abstract | Full text | PDF
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| Brief Communications |
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Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells pp53 - 54 Jonathan S Draper, Kath Smith, Paul Gokhale, Harry D Moore, Edna Maltby, Julie Johnson, Lorraine Meisner, Thomas P Zwaka, James A Thomson
& Peter W Andrews Published online: 07 December 2003 | doi:10.1038/nbt922 Abstract | Full text | PDF
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| Supplementary Information See also: News and Views by Pera |
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| Articles |
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Complete genome sequence of the metabolically versatile photosynthetic bacterium Rhodopseudomonas palustris pp55 - 61 Frank W Larimer, Patrick Chain, Loren Hauser, Jane Lamerdin, Stephanie Malfatti, Long Do, Miriam L Land, Dale A Pelletier, J Thomas Beatty, Andrew S Lang, F Robert Tabita, Janet L Gibson, Thomas E Hanson, Cedric Bobst, Janelle L Torres y Torres, Caroline Peres, Faith H Harrison, Jane Gibson
& Caroline S Harwood Published online: 14 December 2003 | doi:10.1038/nbt923 Abstract | Full text | PDF
(386K)
| Supplementary Information See also: News and Views by Wall |
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Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways pp62 - 69 Ainslie B Parsons, Renée L Brost, Huiming Ding, Zhijian Li, Chaoying Zhang, Bilal Sheikh, Grant W Brown, Patricia M Kane, Timothy R Hughes
& Charles Boone Published online: 07 December 2003 | doi:10.1038/nbt919 Abstract | Full text | PDF
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| Supplementary Information See also: News and Views by Stockwell |
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Systemic tumor targeting and killing by Sindbis viral vectors pp70 - 77 Jen-Chieh Tseng, Brandi Levin, Alicia Hurtado, Herman Yee, Ignacio Perez de Castro, Maria Jimenez, Peter Shamamian, Ruzhong Jin, Richard P Novick, Angel Pellicer
& Daniel Meruelo Published online: 30 November 2003 | doi:10.1038/nbt917 Abstract | Full text | PDF
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Gaining confidence in high-throughput protein interaction networks pp78 - 85 Joel S Bader, Amitabha Chaudhuri, Jonathan M Rothberg
& John Chant Published online: 14 December 2003 | doi:10.1038/nbt924 Abstract | Full text | PDF
(275K)
| Supplementary Information See also: News and Views by Uetz & Pankratz |
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Principles of transcriptional control in the metabolic network of Saccharomyces cerevisiae pp86 - 92 Jan Ihmels, Ronen Levy
& Naama Barkai Published online: 30 November 2003 | doi:10.1038/nbt918 Abstract | Full text | PDF
(157K)
| Supplementary Information |
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| Letters |
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Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping pp93 - 97 Sungjee Kim, Yong Taik Lim, Edward G Soltesz, Alec M De Grand, Jaihyoung Lee, Akira Nakayama, J Anthony Parker, Tomislav Mihaljevic, Rita G Laurence, Delphine M Dor, Lawrence H Cohn, Moungi G Bawendi
& John V Frangioni Published online: 07 December 2003 | doi:10.1038/nbt920 Abstract | Full text | PDF
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| Supplementary Information See also: News and Views by Uren |
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Unraveling protein interaction networks with near-optimal efficiency pp98 - 103 Michael Lappe
& Liisa Holm Published online: 07 December 2003 | doi:10.1038/nbt921 Abstract | Full text | PDF
(302K)
| Supplementary Information |
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Systematic identification of sense-antisense transcripts in mammalian cells pp104 - 108 Øystein Røsok
& Mouldy Sioud Published online: 14 December 2003 | doi:10.1038/nbt925 Abstract | Full text | PDF
(291K)
| Supplementary Information |
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| Resources | Top |
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| Patents |
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Patent protection for protein structure analysis pp109 - 112 Itsuki Shimbo, Rie Nakajima, Shigeyuki Yokoyama
& Koichi Sumikura doi:10.1038/nbt0104-109 Abstract | Full text | PDF
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Recent patent applications in proteomics p113 doi:10.1038/nbt0104-113 Full text | PDF
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| People |
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People pp115 - 117 doi:10.1038/nbt0104-115 Full text | PDF
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| New on the Market |
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Lab automation & Proteomics p119 doi:10.1038/nbt0104-119 Full text | PDF
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| Quiz |
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The Nature Biotechnology 2004 New Year Quiz pp121 - 122 doi:10.1038/nbt0104-121 Full text | PDF
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| Bioentrepreneur | Top |
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| Bioenews |
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Humboldt University beefs up technology transfer pp123 - 124 Martina Habeck Published online: 13 November 2003 | doi:10.1038/bioent781
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Scripps lured to Sunshine State pp124 - 125 Aaron Bouchie Published online: 20 November 2003 | doi:10.1038/bioent782
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France critiques its incubators before refinancing p126 Sabine Louët Published online: 04 December 2003 | doi:10.1038/bioent784 Reprinted with some modification from the Bioentrepreneur web portal (http://www.nature.com/bioent)
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| Building a business |
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Proactive accounting: a key factor in the success of biotechnology startups pp127 - 129 Christian C. Jester Published online: 24 November 2003 | doi:10.1038/bioent779 Reprinted with some modification from the Bioentrepreneur web portal (http://www.nature.com/bioent)
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| Naturejobs | Top |
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| Careers and Recruitment |
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Does your chairman need to be Superman? pp131 - 132 Nicolas Hollanders doi:10.1038/nbt0104-131 Abstract | Full text | PDF
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