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Nature Biotechnology
ISSUE
August 2003, Volume 21 No 8
In This Issue
Editorials
NewsIn Brief
Opinion and CommentCorrespondence | Commentary | Fool's Corner | Book Review
Features
News and ViewsNews and Views
ResearchPerspective | Articles | Letters | Errata | Corrigenda
ResourcesPatents | People | New on the Market
NaturejobsCareers and Recruitment
About the cover
In This Issue Top
PDF
Editorials Top
A piece of history p831
doi:10.1038/nbt0803-831a
Full text | PDF (113K)
Number crunching p831
doi:10.1038/nbt0803-831b
Full text | PDF (113K)
News Top
Public markets show signs of life pp833 - 834
Peter Mitchell
doi:10.1038/nbt0803-833
Full text | PDF (192K)
US courts narrow patent exemptions p834
Jeffrey L Fox
doi:10.1038/nbt0803-834
Full text | PDF (151K)
GM labeling in China beset by problems pp835 - 836
Hepeng Jia
doi:10.1038/nbt0803-835
Full text | PDF (324K)
Illumina tussles in court with ABI pp836 - 837
Kendall Powell
doi:10.1038/nbt0803-836
Full text | PDF (227K)
US government previews biotech survey pp837 - 838
Alexandra Goho
doi:10.1038/nbt0803-837
Full text | PDF (222K)
EU directive on clinical trials penalizes small sponsors p838
Anna Meldolesi
doi:10.1038/nbt0803-838
Full text | PDF (205K)
In Brief
News in Brief pp839 - 842
doi:10.1038/nbt0803-839
Full text | PDF (388K)
Opinion and Comment Top
Correspondence
Hybrid vigor p843
Keith Williams
doi:10.1038/nbt0803-843a
Full text | PDF (136K)
Rediscovering plant-based drugs pp843 - 844
John Littleton, Deane Falcone & H. Maelor Davies
doi:10.1038/nbt0803-843b
Full text | PDF (155K)
Data integration—connecting the dots pp844 - 845
David B. Searls
doi:10.1038/nbt0803-844
Full text | PDF (185K)  | Supplementary Information
Genomic databases yield novel bioplastic producers pp845 - 846
Vipin Chandra Kalia, Ashwini Chauhan, Goutam Bhattacharyya & Rashmi
doi:10.1038/nbt0803-845
Full text | PDF (183K)
Commentary
Biotechnology partnerships—medicine for an ailing industry? pp847 - 848
John DeLamarter
doi:10.1038/nbt0803-847
Full text | PDF (84K)
The science and politics of plant biotechnology—a personal perspective pp849 - 851
Indra K Vasil
doi:10.1038/nbt0803-849
Full text | PDF (90K)
Rethinking US leadership in food biotechnology pp852 - 854
Michael R. Taylor
doi:10.1038/nbt0803-852
Full text | PDF (84K)
Fool's Corner
The stampede to convertibles p855
Tom Jacobs
doi:10.1038/nbt0803-855
Full text | PDF (60K)
Book Review
Defusing an ancient debate pp857 - 858
Reviewed by: Alan McHughen
doi:10.1038/nbt0803-857
Full text | PDF (166K)
Features Top
Screening for content—the evolution of high throughput pp859 - 864
Alan Dove
doi:10.1038/nbt0803-859
Abstract | Full text | PDF (912K)
Biopharmaceutical benchmarks—2003 pp865 - 870
Gary Walsh
doi:10.1038/nbt0803-865
Abstract | Full text | PDF (337K)
News and Views Top
Thrombi—beware of red cells bearing gifts pp871 - 872
Kenneth Ouriel
doi:10.1038/nbt0803-871
Abstract | Full text | PDF (154K)
See also: Research by Murciano et al.
Rise of the nanomachines pp872 - 873
Stephen J Russell
doi:10.1038/nbt0803-872
Abstract | Full text | PDF (101K)
See also: Research by Yamada et al.
Constructing dwarf rice pp873 - 874
Peter Hedden
doi:10.1038/nbt0803-873
Abstract | Full text | PDF (235K)
See also: Research by Sakamoto et al.
Plant metabolic profiling en route to destination pp875 - 876
Barbara J Mazur
doi:10.1038/nbt0803-875
Abstract | Full text | PDF (816K)
News and Views
Research notes p877
doi:10.1038/nbt0803-877
Full text | PDF (226K)
Research Top
Perspective
Chemical discovery and global gene expression analysis in zebrafish pp879 - 883
Franz B Pichler, Sophie Laurenson, Liam C Williams, Andrew Dodd, Brent R Copp & Donald R Love
Published online: 31 July 2003 | doi:10.1038/nbt852
Abstract | Full text | PDF (720K)
Articles
Nanoparticles for the delivery of genes and drugs to human hepatocytes pp885 - 890
Tadanori Yamada, Yasushi Iwasaki, Hiroko Tada, Hidehiko Iwabuki, Marinee KL Chuah, Thierry VandenDriessche, Hideki Fukuda, Akihiko Kondo, Masakazu Ueda, Masaharu Seno, Katsuyuki Tanizawa & Shun'ichi Kuroda
Published online: 29 June 2003 | doi:10.1038/nbt843
Abstract | Full text | PDF (816K)
See also: News and Views by Russell
Prophylactic fibrinolysis through selective dissolution of nascent clots by tPA-carrying erythrocytes pp891 - 896
Juan-Carlos Murciano, Sandra Medinilla, Donald Eslin, Elena Atochina, Douglas B Cines & Vladimir R Muzykantov
Published online: 06 July 2003 | doi:10.1038/nbt846
Abstract | Full text | PDF (1,125K)
See also: News and Views by Ouriel
A transgenic mouse model of the ubiquitin/proteasome system pp897 - 902
Kristina Lindsten, Victoria Menéndez-Benito, Maria G Masucci & Nico P Dantuma
Published online: 20 July 2003 | doi:10.1038/nbt851
Abstract | Full text | PDF (964K)
Dendritic cells, engineered to secrete a T-cell receptor mimic peptide, induce antigen-specific immunosuppression in vivo pp903 - 908
Karsten Mahnke, Yingjie Qian, Jürgen Knop & Alexander H Enk
Published online: 29 June 2003 | doi:10.1038/nbt842
Abstract | Full text | PDF (356K)
Genetic manipulation of gibberellin metabolism in transgenic rice pp909 - 913
Tomoaki Sakamoto, Yoichi Morinaka, Kanako Ishiyama, Masatomo Kobayashi, Hironori Itoh, Toshiaki Kayano, Shuichi Iwahori, Makoto Matsuoka & Hiroshi Tanaka
Published online: 13 July 2003 | doi:10.1038/nbt847
Abstract | Full text | PDF (695K)
See also: News and Views by Hedden
Engineering tolerance and accumulation of lead and cadmium in transgenic plants pp914 - 919
Won-Yong Song, Eun Ju Sohn, Enrico Martinoia, Yong Jik Lee, Young-Yell Yang, Michal Jasinski, Cyrille Forestier, Inwhan Hwang & Youngsook Lee
Published online: 20 July 2003 | doi:10.1038/nbt850
Abstract | Full text | PDF (740K)
Letters
A proteomics approach to understanding protein ubiquitination pp921 - 926
Junmin Peng, Daniel Schwartz, Joshua E Elias, Carson C Thoreen, Dongmei Cheng, Gerald Marsischky, Jeroen Roelofs, Daniel Finley & Steven P Gygi
Published online: 20 July 2003 | doi:10.1038/nbt849
Abstract | Full text | PDF (331K)  | Supplementary Information
Metabolic labeling of C. elegans and D. melanogaster for quantitative proteomics pp927 - 931
Jeroen Krijgsveld, René F Ketting, Tokameh Mahmoudi, Janik Johansen, Marta Artal-Sanz, C Peter Verrijzer, Ronald H A Plasterk & Albert J R Heck
Published online: 13 July 2003 | doi:10.1038/nbt848
Abstract | Full text | PDF (461K)
Transfection-independent production of alphavirus replicon particles based on poxvirus expression vectors pp932 - 935
Nikos Vasilakis, Darlene Falvey, Seema S Gangolli, John Coleman, Jacek Kowalski, Stephen A Udem, Timothy J Zamb & Gerald R Kovacs
Published online: 06 July 2003 | doi:10.1038/nbt845
Abstract | Full text | PDF (489K)
Targeting of proteins to membranes through hedgehog auto-processing pp936 - 940
Sylvie Vincent, Abraham Thomas, Bradley Brasher & John D Benson
Published online: 13 July 2003 | doi:10.1038/nbt844
Abstract | Full text | PDF (1,044K)  | Supplementary Information
Errata
Development of potent monoclonal antibody auristatin conjugates for cancer therapy p941
Svetlana O Doronina, Brian E Toki, Michael Y Torgov, Brian A Mendelsohn, Charles G Cerveny, Dana F Chace, Ron L DeBlanc, R Patrick Gearing, Tim D Bovee, Clay B Siegall, Joseph A Francisco, Alan F Wahl, Damon L Meyer & Peter D Senter
doi:10.1038/nbt0803-941a
Full text | PDF (44K)
Corrigenda
A model of molecular interactions on short oligonucleotide microarrays p941
Li Zhang, Michael F Miles & Kenneth D Aldape
doi:10.1038/nbt0803-941b
Full text | PDF (44K)
Resources Top
Patents
Is the viability of the Lilly doctrine on the decline? pp943 - 944
Barbara Webb Walker & Sherry M Carty
doi:10.1038/nbt0803-943
Abstract | Full text | PDF (79K)
Recent patents in drug discovery p945
doi:10.1038/nbt0803-945
Full text | PDF (33K)
People
People p947
doi:10.1038/nbt0803-947
Full text | PDF (68K)
New on the Market
Drug discovery & development p949
doi:10.1038/nbt0803-949
Full text | PDF (398K)
Naturejobs Top
Careers and Recruitment
The learning curve pp951 - 952
Karen Kreeger
doi:10.1038/nbt0803-951
Abstract | Full text | PDF (63K)
  Top
 
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Nature Biotechnology
ISSN: 1087-0156
EISSN: 1546-1696
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