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| Editorials | Top |
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Hybrid rigor mortis p585
doi:10.1038/nbt0603-585a
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(57K)
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Getting a facelift p585
doi:10.1038/nbt0603-585b
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(57K)
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| News | Top |
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Germany contemplates new biotech tax scheme pp587 - 588
Peter Mitchell
doi:10.1038/nbt0603-587
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(134K)
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EU stalls on funding of ES cell research pp588 - 589
Anna Meldolesi
doi:10.1038/nbt0603-588
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(135K)
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Agbiotech climbs Africa's agenda p589
Jeffrey L. Fox
doi:10.1038/nbt0603-589
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(74K)
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US FDA contemplates collection of pharmacogenomic data p590
Jim Kling
doi:10.1038/nbt0603-590a
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(74K)
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India dawdles over Bt-cotton pp590 - 591
K.S. Jayaraman
doi:10.1038/nbt0603-590b
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(194K)
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| In Brief |
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News in Brief pp593 - 595
doi:10.1038/nbt0603-593
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(252K)
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| Opinion and Comment | Top |
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| Correspondence |
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The challenge of industrializing proteomics p597
Mark P. Molloy
doi:10.1038/nbt0603-597a
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(119K)
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Clarifying press before paper pp597 - 598
Allison A. Snow
& Diana Pilson
doi:10.1038/nbt0603-597b
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(191K)
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Identity tags p598
Urs Pauli
doi:10.1038/nbt0603-598
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(122K)
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| Commentary |
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Making 'safety first' a reality for biotechnology products pp599 - 601
Anne R Kapuscinski, Robert M Goodman, Stuart D Hann, Lawrence R Jacobs, Emily E Pullins, Charles S Johnson, Jean D Kinsey, Ronald L Krall, Antonio GM La Viña, Margaret G Mellon
& Vernon W Ruttan
doi:10.1038/nbt0603-599
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(87K)
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Putting nature back into drug discovery p602
Lutz Müller-Kuhrt
doi:10.1038/nbt0603-602
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(72K)
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| Fool's Corner |
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Hidden in plain view p603
Tom Jacobs
doi:10.1038/nbt0603-603
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(60K)
| Supplementary Information |
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| Book Review |
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The biotech speculator p605
Reviewed by: Robert Teitelman
doi:10.1038/nbt0603-605
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(104K)
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| Features | Top |
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Public biotechnology 2002—the numbers pp607 - 612
Riku Lähteenmäki
& Laura DeFrancesco
doi:10.1038/nbt0603-607
Abstract | Full text | PDF
(132K)
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US venture capital for biotechnology pp613 - 617
Mark D Dibner, Melanie Trull
& Michael Howell
doi:10.1038/nbt0603-613
Abstract | Full text | PDF
(165K)
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Value creation and sharing among universities, biotechnology and pharma pp618 - 624
Mark G Edwards, Fiona Murray
& Robert Yu
doi:10.1038/nbt0603-618
Abstract | Full text | PDF
(149K)
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| News and Views | Top |
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Targeting mammalian genes—rats join in and mice move ahead pp625 - 627
Janet Rossant
doi:10.1038/nbt0603-625
Abstract | Full text | PDF
(213K)
See also: Research by Zan et al. | Research by Valenzuela et al. |
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Mass spectrometry provides sweet inspiration pp627 - 629
Hudson Freeze
doi:10.1038/nbt0603-627
Abstract | Full text | PDF
(127K)
See also: Research by Zhang et al. | Research by Kaji et al. |
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RNAi puts a lid on virus replication pp629 - 630
Raul Andino
doi:10.1038/nbt0603-629
Abstract | Full text | PDF
(140K)
See also: Research by McCaffrey et al. |
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Plugging metal connectors into enzymes pp631 - 632
Adam Heller
doi:10.1038/nbt0603-631
Abstract | Full text | PDF
(114K)
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| News and Views |
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Research notes p633
doi:10.1038/nbt0603-633
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(404K)
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| Research | Top |
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| Brief Communications |
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Expression profiling reveals off-target gene regulation by RNAi pp635 - 637
Aimee L Jackson, Steven R Bartz, Janell Schelter, Sumire V Kobayashi, Julja Burchard, Mao Mao, Bin Li, Guy Cavet
& Peter S Linsley
Published online: 18 May 2003 | doi:10.1038/nbt831
Abstract | Full text | PDF
(877K)
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| Articles |
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Inhibition of hepatitis B virus in mice by RNA interference pp639 - 644
Anton P McCaffrey, Hiroyuki Nakai, Kusum Pandey, Zan Huang, Felix H Salazar, Hui Xu, Stefan F Wieland, Patricia L Marion
& Mark A Kay
Published online: 12 May 2003 | doi:10.1038/nbt824
Abstract | Full text | PDF
(1,396K)
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See also: News and Views by Andino |
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Production of knockout rats using ENU mutagenesis and a yeast-based
screening assay pp645 - 651
Yunhong Zan, Jill D Haag, Kai-Shun Chen, Laurie A Shepel, Don Wigington, Yu-Rong Wang, Rong Hu, Christine C Lopez-Guajardo, Heidi L Brose, Katherine I Porter, Rachel A Leonard, Andrew A Hitt, Stacy L Schommer, Anu F Elegbede
& Michael N Gould
Published online: 18 May 2003 | doi:10.1038/nbt830
Abstract | Full text | PDF
(647K)
| Supplementary Information
See also: News and Views by Rossant |
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High-throughput engineering of the mouse genome coupled with
high-resolution expression analysis pp652 - 659
David M Valenzuela, Andrew J Murphy, David Frendewey, Nicholas W Gale, Aris N Economides, Wojtek Auerbach, William T Poueymirou, Niels C Adams, Jose Rojas, Jason Yasenchak, Rostislav Chernomorsky, Marylene Boucher, Andrea L Elsasser, Lakeisha Esau, Jenny Zheng, Jennifer A Griffiths, Xiaorong Wang, Hong Su, Yingzi Xue, Melissa G Dominguez, Irene Noguera, Richard Torres, Lynn E Macdonald, A Francis Stewart, Thomas M DeChiara
& George D Yancopoulos
Published online: 05 May 2003 | doi:10.1038/nbt822
Abstract | Full text | PDF
(1,265K)
| Supplementary Information
See also: News and Views by Rossant |
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Identification and quantification of N-linked glycoproteins using
hydrazide chemistry, stable isotope labeling and mass spectrometry pp660 - 666
Hui Zhang, Xiao-jun Li, Daniel B Martin
& Ruedi Aebersold
Published online: 18 May 2003 | doi:10.1038/nbt827
Abstract | Full text | PDF
(315K)
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See also: News and Views by Freeze |
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Lectin affinity capture, isotope-coded tagging and mass spectrometry
to identify N-linked glycoproteins pp667 - 672
Hiroyuki Kaji, Haruna Saito, Yoshio Yamauchi, Takashi Shinkawa, Masato Taoka, Jun Hirabayashi, Ken-ichi Kasai, Nobuhiro Takahashi
& Toshiaki Isobe
Published online: 18 May 2003 | doi:10.1038/nbt829
Abstract | Full text | PDF
(181K)
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See also: News and Views by Freeze |
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Multiplexed genotyping with sequence-tagged molecular inversion
probes pp673 - 678
Paul Hardenbol, Johan Banér, Maneesh Jain, Mats Nilsson, Eugeni A Namsaraev, George A Karlin-Neumann, Hossein Fakhrai-Rad, Mostafa Ronaghi, Thomas D Willis, Ulf Landegren
& Ronald W Davis
Published online: 05 May 2003 | doi:10.1038/nbt821
Abstract | Full text | PDF
(388K)
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Turnover-based in vitro selection and evolution of biocatalysts
from a fully synthetic antibody library pp679 - 685
Sandro Cesaro-Tadic, Dimitrios Lagos, Annemarie Honegger, James H Rickard, Lynda J Partridge, G Michael Blackburn
& Andreas Plückthun
Published online: 18 May 2003 | doi:10.1038/nbt828
Abstract | Full text | PDF
(438K)
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| Letters |
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Discovering potent and selective reversible inhibitors of enzymes in
complex proteomes pp687 - 691
Donmienne Leung, Christophe Hardouin, Dale L Boger
& Benjamin F Cravatt
Published online: 12 May 2003 | doi:10.1038/nbt826
Abstract | Full text | PDF
(643K)
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High-throughput classification of yeast mutants for functional
genomics using metabolic footprinting pp692 - 696
Jess Allen, Hazel M Davey, David Broadhurst, Jim K Heald, Jem J Rowland, Stephen G Oliver
& Douglas B Kell
Published online: 12 May 2003 | doi:10.1038/nbt823
Abstract | Full text | PDF
(383K)
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Global protein function prediction from protein-protein interaction
networks pp697 - 700
Alexei Vazquez, Alessandro Flammini, Amos Maritan
& Alessandro Vespignani
Published online: 12 May 2003 | doi:10.1038/nbt825
Abstract | Full text | PDF
(113K)
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| Resources | Top |
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| Patents |
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Protecting rights to early-stage technology pp701 - 703
Michael J Shuster, Henry Su
& Sasha Blaug
doi:10.1038/nbt0603-701
Abstract | Full text | PDF
(85K)
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Recent patents in plant biotechnology p705
doi:10.1038/nbt0603-705
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(36K)
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| People |
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People p707
doi:10.1038/nbt0603-707
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(91K)
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| New on the Market |
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Genetic analysis & Centrifugation pp709 - 711
doi:10.1038/nbt0603-709
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(373K)
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| Naturejobs | Top |
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| Careers and Recruitment |
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New immigration laws affect US biotechnology pp713 - 714
Pamela S Cowan
doi:10.1038/nbt0603-713
Abstract | Full text | PDF
(64K)
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