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| In This Issue |  Top |
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| Editorial | Top |
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Patenting pieces of people p341
doi:10.1038/nbt0403-341
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(53K)
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| Business and Regulatory News | Top |
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| Analysis |
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UK bidding war amidst merger mania pp343 - 344
Peter Mitchell
doi:10.1038/nbt0403-343
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(722K)
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FDA panel recommends easing gene therapy trial limits pp344 - 345
Jeffrey L. Fox
doi:10.1038/nbt0403-344
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US Patent Office strategic plan may penalize biotechs pp345 - 346
Debra Robertson
doi:10.1038/nbt0403-345
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(70K)
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Italy employs further GMO delay tactics p346
Anna Meldolesi
doi:10.1038/nbt0403-346a
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(58K)
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US food aid still under GM cloud pp346 - 347
K.S. Jayaraman
doi:10.1038/nbt0403-346b
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(557K)
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Industry ponders reimbursement crisis pp347 - 348
Aaron Bouchie
doi:10.1038/nbt0403-347
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(555K)
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| In Brief |
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In Brief pp349 - 351
doi:10.1038/nbt0403-349
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(392K)
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| Opinion | Top |
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| Commentary |
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Press before paper—when media and science collide pp353 - 354
C. Neal Stewart Jr.
doi:10.1038/nbt0403-353
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(63K)
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The biotechnology bubble machine pp355 - 356
David Rasnick
doi:10.1038/nbt0403-355
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(64K)
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| Fool's Corner |
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Fighting company spin p357
Tom Jacobs
doi:10.1038/nbt0403-357
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(47K)
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| Correspondence |
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Xeno—still stuck without  Gal pp359 - 360
Yoshihiro Miyata
& Jeffrey L. Platt
doi:10.1038/nbt0403-359
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(334K)
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European agbiotech crisis? p360
Trevor M. Fenning
& Jonathan Gershenzon
doi:10.1038/nbt0403-360
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(44K)
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| Features | Top |
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Slimy business—the biotechnology of biofilms pp361 - 365
Beth Schachter
doi:10.1038/nbt0403-361
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(1,003K)
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Who is driving biotechnology acceptance? pp366 - 369
Nicholas Kalaitzandonakes
& Jos Bijman
doi:10.1038/nbt0403-366
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(490K)
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| Research News | Top |
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| News and Views |
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Antisense starts making more sense pp371 - 372
Gordon G. Carmichael
doi:10.1038/nbt0403-371
Abstract | Full text | PDF
(536K)
See also: Research by Yelin et al. |
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Taming ricin toxin pp372 - 374
Robert J. Kreitman
doi:10.1038/nbt0403-372
Abstract | Full text | PDF
(186K)
See also: Research by Smallshaw et al. |
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Jumping genes and containment pp374 - 375
Henry Daniell
& Christopher L. Parkinson
doi:10.1038/nbt0403-374
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(419K)
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| In Brief |
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In Brief p377
doi:10.1038/nbt0403-377
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(196K)
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| Research | Top |
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| Articles |
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Widespread occurrence of antisense transcription in the human
genome pp379 - 386
Rodrigo Yelin, Dvir Dahary, Rotem Sorek, Erez Y. Levanon, Orly Goldstein, Avi Shoshan, Alex Diber, Sharon Biton, Yael Tamir, Rami Khosravi, Sergey Nemzer, Elhanan Pinner, Shira Walach, Jeanne Bernstein, Kinneret Savitsky
& Galit Rotman
Published online: 17 March 2003 | doi:10.1038/nbt808
Abstract | Full text | PDF
(3,054K)
| Supplementary Information
See also: Research News by Carmichael |
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Genetic engineering of an immunotoxin to eliminate pulmonary vascular
leak in mice pp387 - 391
Joan E. Smallshaw, Victor Ghetie, Jose Rizo, John R. Fulmer, Linda L. Trahan, Maria-Ana Ghetie
& Ellen S. Vitetta
Published online: 10 March 2003 | doi:10.1038/nbt800
Abstract | Full text | PDF
(635K)
See also: Research News by Kreitman |
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Immunotargeting of catalase to the pulmonary endothelium alleviates oxidative stress and reduces acute lung transplantation injury pp392 - 398
Benjamin D. Kozower, Melpo Christofidou-Solomidou, Thomas D. Sweitzer, Silvia Muro, Donald G. Buerk, Charalambos C. Solomides, Steven M. Albelda, G. Alexander Patterson
& Vladimir R. Muzykantov
Published online: 24 March 2003 | doi:10.1038/nbt806
Abstract | Full text | PDF
(1,865K)
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Synthesis of a poly(vinylpyrrolidone-co
-dimethyl maleic
anhydride) co-polymer and its application for renal drug targeting pp399 - 404
Haruhiko Kamada, Yasuo Tsutsumi, Keiko Sato-Kamada, Yoko Yamamoto, Yasuo Yoshioka, Takayuki Okamoto, Shinsaku Nakagawa, Satoshi Nagata
& Tadanori Mayumi
Published online: 03 March 2003 | doi:10.1038/nbt798
Abstract | Full text | PDF
(1,478K)
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Serial in vivo imaging of the targeted migration of human
HSV-TK-transduced antigen-specific lymphocytes pp405 - 413
Guenther Koehne, Mikhail Doubrovin, Ekaterina Doubrovina, Pat Zanzonico, Humilidad F. Gallardo, Anna Ivanova, Julius Balatoni, Julie Teruya-Feldstein, Glenn Heller, Chad May, Vladimir Ponomarev, Shutian Ruan, Ronald Finn, Ronald G. Blasberg, William Bornmann, Isabelle Riviere, Michel Sadelain, Richard J. O'Reilly, Steven M. Larson
& Juri G. Gelovani Tjuvajev
Published online: 24 March 2003 | doi:10.1038/nbt805
Abstract | Full text | PDF
(2,323K)
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Enhancement of therapeutic protein in vivo activities through glycoengineering pp414 - 421
Steve Elliott, Tony Lorenzini, Sheilah Asher, Ken Aoki, David Brankow, Lynette Buck, Leigh Busse, David Chang, Janis Fuller, James Grant, Natasha Hernday, Martha Hokum, Sylvia Hu, Andrew Knudten, Nancy Levin, Renee Komorowski, Frank Martin, Rachell Navarro, Timothy Osslund, Gary Rogers, Norma Rogers, Geri Trail
& Joan Egrie
Published online: 03 March 2003 | doi:10.1038/nbt799
Abstract | Full text | PDF
(1,624K)
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Semisynthetic production of unnatural L--amino acids by metabolic engineering of the cysteine-biosynthetic pathway pp422 - 427
Thomas H. P. Maier
Published online: 17 March 2003 | doi:10.1038/nbt807
Abstract | Full text | PDF
(118K)
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Multiherbicide tolerance conferred by AtPgp1 and apyrase overexpression in Arabidopsis thaliana pp428 - 433
Brian Windsor, Stanley J. Roux
& Alan Lloyd
Published online: 17 March 2003 | doi:10.1038/nbt809
Abstract | Full text | PDF
(1,684K)
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| Technical Reports |
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Identification of co-regulated genes through Bayesian clustering of
predicted regulatory binding sites pp435 - 439
Zhaohui S. Qin, Lee Ann McCue, William Thompson, Linda Mayerhofer, Charles E. Lawrence
& Jun S. Liu
Published online: 10 March 2003 | doi:10.1038/nbt802
Abstract | Full text | PDF
(1,678K)
| Supplementary Information |
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A transformation method for obtaining marker-free plants of a
cross-pollinating and vegetatively propagated crop pp439 - 442
Nick de Vetten, Anne-Marie Wolters, Krit Raemakers, Ingrid van der Meer, Renaldo ter Stege, Els Heeres, Paul Heeres
& Richard Visser
Published online: 10 March 2003 | doi:10.1038/nbt801
Abstract | Full text | PDF
(847K)
| Supplementary Information |
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Engineering the mouse genome with bacterial artificial chromosomes to create multipurpose alleles pp443 - 447
Giuseppe Testa, Youming Zhang, Kristina Vintersten, Vladimir Benes, W.W.M. Pim Pijnappel, Ian Chambers, Andrew J.H. Smith, Austin G. Smith
& A. Francis Stewart
Published online: 10 March 2003 | doi:10.1038/nbt804
Abstract | Full text | PDF
(1,231K)
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Site-specific gene targeting in mouse embryonic stem cells with intact bacterial artificial chromosomes pp447 - 451
Yi Yang
& Brian Seed
Published online: 10 March 2003 | doi:10.1038/nbt803
Abstract | Full text | PDF
(1,368K)
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| Corrigenda |
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Corrigendum: Kindling fluorescent proteins for precise in vivo
photolabeling p452
Dmitriy M. Chudakov, Vsevolod V. Belousov, Andrey G. Zaraisky, Vladimir V. Novoselov, Dmitry B. Staroverov, Dmitry B. Zorov, Sergey Lukyanov
& Konstantin A. Lukyanov
doi:10.1038/nbt0403-452a
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(37K)
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Corrigendum: Immunofluorescent labeling of cancer marker Her2 and
other cellular targets with semiconductor quantum dots p452
Xingyong Wu, Hongjian Liu, Jianquan Liu, Kari N. Haley, Joseph A. Treadway, J. Peter Larson, Nianfeng Ge, Frank Peale
& Marcel P. Bruchez
doi:10.1038/nbt0403-452b
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(37K)
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Corrigendum: Human zinc fingers as building blocks in the
construction of artificial transcription factors p452
Kwang-Hee Bae, Young Do Kwon, Hyun-Chul Shin, Moon-Sun Hwang, Eun-Hyun Ryu, Kyung-Soon Park, Hyo-Young Yang, Dong-ki Lee, Yangsoon Lee, Jinwoo Park, Heung Sun Kwon, Hyun-Won Kim, Byung-Il Yeh, Hyean-Woo Lee, Soon Hyung Sohn, Joonho Yoon, Wongi Seol
& Jin-Soo Kim
doi:10.1038/nbt0403-452c
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(37K)
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| Errata |
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Erratum: Decoding the literature on genetic variation p452
Roger Coronini, Marie-Angèle de Looze, Pierre Puget, Gérard Bley
& Shyama V. Ramani
doi:10.1038/nbt0403-452d
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(37K)
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| Resources | Top |
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| Patents |
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No room for experiment: the Federal Circuit's narrow construction of the experimental use defense p453
S. Peter Ludwig
& Jason C. Chumney
doi:10.1038/nbt0403-453
Abstract | Full text | PDF
(50K)
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Recent patents in RNA interference p455
doi:10.1038/nbt0403-455
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(25K)
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| People |
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People p457
doi:10.1038/nbt0403-457
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(71K)
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| New on the Market |
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Sample preparation and Enzymes & reagents pp459 - 461
doi:10.1038/nbt0403-459
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(1,080K)
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| Naturejobs | Top |
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| Careers and Recruitment |
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Taiwan: Biotech vision pp463 - 464
David Cyranoski
doi:10.1038/nbt0403-463
Abstract | Full text | PDF
(1,772K)
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