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| This focus brings together a selection of articles on new techniques in optical imaging. |
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| Editorial | Top |
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Focus on Optical Imaging
Out of the shadows p1251
doi:10.1038/nbt1103-1251
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(54K)
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| News | Top |
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US NHGRI launches chemical attack on drug development gap pp1253 - 1254
Ken Garber
Published online: 01 November 2003 | doi:10.1038/nbt905
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(277K)
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Public−private partnerships boost research on neglected
diseases pp1254 - 1255
Sabine Louët
Published online: 01 November 2003 | doi:10.1038/nbt903
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(216K)
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Concerns raised over declining antiinfectives R&D pp1255 - 1256
Jeffrey L. Fox
Published online: 01 November 2003 | doi:10.1038/nbt904
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(218K)
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Japan's biotech sector shows signs of life pp1256 - 1257
Keiko Kandachi
Published online: 01 November 2003 | doi:10.1038/nbt906
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(205K)
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GM confusion in Brazil pp1257 - 1258
Ricardo Bonalume Neto
Published online: 01 November 2003 | doi:10.1038/nbt901
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(216K)
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Benefits of biotech clusters questioned pp1258 - 1259
Cormac Sheridan
Published online: 01 November 2003 | doi:10.1038/nbt902
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(559K)
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Biotech parks proliferate, despite concerns over sustainability pp1259 - 1260
Hepeng Jia
Published online: 01 November 2003 | doi:10.1038/nbt900
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(643K)
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| In Brief |
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News In Brief pp1261 - 1263
doi:10.1038/nbt1103-1261
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(274K)
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| Opinion and Comment | Top |
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| Correspondence |
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Letter 1: Equivocal role of micelles in Eprex adverse events p1265
Janice M Smiell
doi:10.1038/nbt1103-1265a
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(71K)
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Letter 2: Equivocal role of micelles in Eprex adverse events p1265
Huub Schellekens
& Daan J A Crommelin
doi:10.1038/nbt1103-1265b
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(73K)
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Reply to: Equivocal role of micelles in Eprex adverse events p1266
doi:10.1038/nbt1103-1266a
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(84K)
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Chaperonins govern growth of Escherichia coli at low temperatures pp1266 - 1267
Manuel Ferrer, Tatyana N Chernikova, Michail M Yakimov, Peter N Golyshin
& Kenneth N Timmis
doi:10.1038/nbt1103-1266b
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(99K)
| Supplementary Information |
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| Commentary |
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Focus on Optical Imaging
Invention and commercialization in optical bioimaging pp1269 - 1271
Daniel L Farkas
doi:10.1038/nbt1103-1269
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(517K)
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Focus on Optical Imaging
Crystal gazing in optical microscopy pp1272 - 1273
Scott E Fraser
doi:10.1038/nbt1103-1272
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(94K)
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A framework for designing transgenic crops—science, safety and citizen's concerns pp1274 - 1279
Ariane König
doi:10.1038/nbt1103-1274
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(141K)
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Gene medication or genetic modification? The devil is in the details pp1280 - 1281
Grethe S Foss
& Sissel Rogne
doi:10.1038/nbt1103-1280
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(97K)
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The tyranny of 'genethics' p1282
Leigh Turner
doi:10.1038/nbt1103-1282
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(73K)
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| Fool's Corner |
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Why biotech don't pay dividends — yet p1283
Tom Jacobs
doi:10.1038/nbt1103-1283
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(95K)
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| Book Review |
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How to sell an industry p1285
Reviewed by: Donna Murray
doi:10.1038/nbt1103-1285
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(104K)
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The rise of European venture capital for biotechnology pp1287 - 1291
Michael Howell, Melanie Trull
& Mark D Dibner
doi:10.1038/nbt1103-1287
Abstract | Full text | PDF
(636K)
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| News and Views | Top |
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Engineering better cytokines pp1293 - 1294
Lawrence Steinman
doi:10.1038/nbt1103-1293
Abstract | Full text | PDF
(115K)
See also: Research by Adams et al. |
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Sequence of a symbiont pp1294 - 1295
Valerie M Williamson
& Harry K Kaya
doi:10.1038/nbt1103-1294
Abstract | Full text | PDF
(185K)
See also: Research by Duchaud et al. |
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Reconstructing genetic networks in yeast pp1295 - 1297
Zhaolei Zhang
& Mark Gerstein
doi:10.1038/nbt1103-1295
Abstract | Full text | PDF
(219K)
See also: Research by Bar-Joseph et al. |
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Playing tag with the yeast proteome pp1297 - 1299
Brenda J Andrews, Gary D Bader
& Charles Boone
doi:10.1038/nbt1103-1297
Abstract | Full text | PDF
(147K)
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Research notes p1301
doi:10.1038/nbt1103-1301
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(180K)
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| Research | Top |
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| Brief Communications |
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Focus on Optical Imaging
Immunofluorescence stimulated emission depletion microscopy pp1303 - 1304
Marcus Dyba, Stefan Jakobs
& Stefan W Hell
Published online: 19 October 2003 | doi:10.1038/nbt897
Abstract | Full text | PDF
(277K)
| Supplementary Information |
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Human antibodies from immunized donors are protective against anthrax toxin in vivo pp1305 - 1306
Martha A Wild, Hong Xin, Toshiaki Maruyama, Mary Jean Nolan, Peter M Calveley, John D Malone, Mark R Wallace
& Katherine S Bowdish
Published online: 12 October 2003 | doi:10.1038/nbt891
Abstract | Full text | PDF
(123K)
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The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens pp1307 - 1313
Eric Duchaud, Christophe Rusniok, Lionel Frangeul, Carmen Buchrieser, Alain Givaudan, Séad Taourit, Stéphanie Bocs, Caroline Boursaux-Eude, Michael Chandler, Jean-François Charles, Elie Dassa, Richard Derose, Sylviane Derzelle, Georges Freyssinet, Sophie Gaudriault, Claudine Médigue, Anne Lanois, Kerrie Powell, Patricia Siguier, Rachel Vincent, Vincent Wingate, Mohamed Zouine, Philippe Glaser, Noël Boemare, Antoine Danchin
& Frank Kunst
Published online: 05 October 2003 | doi:10.1038/nbt886
Abstract | Full text | PDF
(780K)
| Supplementary Information
See also: News and Views by Williamson & Kaya |
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Targeting cytokines to inflammation sites pp1314 - 1320
Gill Adams, Sandrine Vessillier, Hanna Dreja
& Yuti Chernajovsky
Published online: 05 October 2003 | doi:10.1038/nbt888
Abstract | Full text | PDF
(1,208K)
See also: News and Views by Steinman |
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A genetic approach to inactivating chemokine receptors using a modified viral protein pp1321 - 1327
V McNeil Coffield, Qi Jiang
& Lishan Su
Published online: 12 October 2003 | doi:10.1038/nbt889
Abstract | Full text | PDF
(529K)
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E3 gene manipulations affect oncolytic adenovirus activity in immunocompetent tumor models pp1328 - 1335
Yaohe Wang, Gunnel Hallden, Richard Hill, Arthi Anand, Ta-Chiang Liu, Jennelle Francis, Gabriel Brooks, Nick Lemoine
& David Kirn
Published online: 12 October 2003 | doi:10.1038/nbt887
Abstract | Full text | PDF
(1,209K)
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| Letters |
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Computational discovery of gene modules and regulatory networks pp1337 - 1342
Ziv Bar-Joseph, Georg K Gerber, Tong Ihn Lee, Nicola J Rinaldi, Jane Y Yoo, François Robert, D Benjamin Gordon, Ernest Fraenkel, Tommi S Jaakkola, Richard A Young
& David K Gifford
Published online: 12 October 2003 | doi:10.1038/nbt890
Abstract | Full text | PDF
(1,154K)
| Supplementary Information
See also: News and Views by Zhang & Gerstein |
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Enzymatic synthesis of antithrombin III−binding heparan sulfate pentasaccharide pp1343 - 1346
Balagurunathan Kuberan, Miroslaw Z Lech, David L Beeler, Zhengliang L Wu
& Robert D Rosenberg
Published online: 05 October 2003 | doi:10.1038/nbt885
Abstract | Full text | PDF
(201K)
| Supplementary Information |
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| Perspective |
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Focus on Optical Imaging
Toward fluorescence nanoscopy pp1347 - 1355
Stefan W Hell
Published online: 31 October 2003 | doi:10.1038/nbt895
Abstract | Full text | PDF
(675K)
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Focus on Optical Imaging
Second-harmonic imaging microscopy for visualizing biomolecular arrays in cells, tissues and organisms pp1356 - 1360
Paul J Campagnola
& Leslie M Loew
Published online: 31 October 2003 | doi:10.1038/nbt894
Abstract | Full text | PDF
(969K)
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Focus on Optical Imaging
Optical coherence tomography for ultrahigh resolution in vivo imaging pp1361 - 1367
James G Fujimoto
Published online: 31 October 2003 | doi:10.1038/nbt892
Abstract | Full text | PDF
(2,586K)
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| Reviews |
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Focus on Optical Imaging
Nonlinear magic: multiphoton microscopy in the biosciences pp1369 - 1377
Warren R Zipfel, Rebecca M Williams
& Watt W Webb
Published online: 31 October 2003 | doi:10.1038/nbt899
Abstract | Full text | PDF
(809K)
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Focus on Optical Imaging
Near-field optics: from subwavelength illumination to nanometric shadowing pp1378 - 1386
Aaron Lewis, Hesham Taha, Alina Strinkovski, Alexandra Manevitch, Artium Khatchatouriants, Rima Dekhter
& Erich Ammann
Published online: 31 October 2003 | doi:10.1038/nbt898
Abstract | Full text | PDF
(1,210K)
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Focus on Optical Imaging
FRET imaging pp1387 - 1395
Elizabeth A Jares-Erijman
& Thomas M Jovin
Published online: 31 October 2003 | doi:10.1038/nbt896
Abstract | Full text | PDF
(504K)
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| Errata |
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Biopharmaceutical benchmarks—2003 p1396
Gary Walsh
doi:10.1038/nbt1103-1396a
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(45K)
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| Corrigenda |
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Phosphospecific proteolysis for mapping sites of protein phosphorylation p1396
Zachary A Knight, Birgit Schilling, Richard H Row, Denise M Kenski, Bradford W Gibson
& Kevan M Shokat
doi:10.1038/nbt1103-1396b
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(45K)
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| Resources | Top |
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| Patents |
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Past versus present: the importance of tense in patent application examples pp1397 - 1398
Jane E R Potter
& Gargi Talukder
doi:10.1038/nbt1103-1397
Abstract | Full text | PDF
(72K)
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Recent patent applications in gene expression p1399
doi:10.1038/nbt1103-1399
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(32K)
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| People |
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People p1401
doi:10.1038/nbt1103-1401
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(62K)
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| New on the Market |
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Focus on Optical Imaging
Imaging & microscopy pp1403 - 1405
doi:10.1038/nbt1103-1403
Full text | PDF
(452K)
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| Naturejobs | Top |
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| Careers and Recruitment |
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Professional master's degree programs in regulatory affairs and biomedical quality systems pp1407 - 1409
E Dale Sevier, Robert Wang, Larry E Gundersen
& A Stephen Dahms
doi:10.1038/nbt1103-1407
Abstract | Full text | PDF
(84K)
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