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Research
Nature Biotechnology 21, 1337–1342 (1 November 2003) | doi:10.1038/nbt890
Computational discovery of gene modules and regulatory networks
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Abstract
We describe an algorithm for discovering regulatory networks of gene modules, GRAM (Genetic Regulatory Modules), that combines information from genome-wide location and expression data sets. A gene module is defined as a set of coexpressed genes to which the same set of transcription factors binds.
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