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| Editorials | Top |
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Happier, hornier, hairier p1
doi:10.1038/nbt0103-1a
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(52K)
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It's a gas p1
doi:10.1038/nbt0103-1b
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(52K)
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| Business and Regulatory News | Top |
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| Analysis |
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Antisoma−Roche deal—a new kind of buyout? p3
Peter Mitchell
doi:10.1038/nbt0103-3a
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Puzzling industry response to ProdiGene fiasco pp3 - 4
Jeffrey L. Fox
doi:10.1038/nbt0103-3b
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Hyseq−Variagenics merger signals end of the line p5
John Hodgson
doi:10.1038/nbt0103-5
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Europe angers US with strict GM labeling p6
Peter Mitchell
doi:10.1038/nbt0103-6a
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(57K)
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New products highlight ambiguity of orphan drug law pp6 - 7
Brian Reid
doi:10.1038/nbt0103-6b
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(62K)
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| In Brief |
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In Brief pp9 - 11
doi:10.1038/nbt0103-9
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(532K)
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| Opinion | Top |
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| Commentary |
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The sigmoidal curve of cancer pp13 - 14
Roberto P. Stock
& Harvey Bialy
doi:10.1038/nbt0103-13
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(223K)
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Cytokines—strategic weapons in germ warfare? pp15 - 16
Leonid Margolis
doi:10.1038/nbt0103-15
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(506K)
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| Fool's Corner |
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Who's minding the store? p17
Tom Jacobs
doi:10.1038/nbt0103-17
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(47K)
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| Book Review |
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What's in the Book of Life? p19
Reviewed by: Staffan Müller-Wille
doi:10.1038/nbt0103-19
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(49K)
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| Feature | Top |
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Decoding the literature on genetic variation pp21 - 29
Roger Coronini, Marie-Angèle de Looze, Pierre Puget, Gérard Bley
& Shyama V. Ramani
doi:10.1038/nbt0103-21
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(106K)
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| Research News | Top |
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| News and Views |
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The master mammal pp31 - 32
Arthur T. Sands
doi:10.1038/nbt0103-31
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Quantum dots finally come of age pp32 - 33
Thomas M. Jovin
doi:10.1038/nbt0103-32
Abstract | Full text | PDF
(73K)
See also: Research by Wu et al. | Research by Jaiswal et al. |
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Human therapeutic proteins from silkworms pp34 - 35
Florian M. Wurm
doi:10.1038/nbt0103-34
Abstract | Full text | PDF
(406K)
See also: Research by Tomita et al. |
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Antibody jabs for plant enzymes pp35 - 36
Udo Conrad
& Uwe Sonnewald
doi:10.1038/nbt0103-35
Abstract | Full text | PDF
(91K)
See also: Research by Jobling et al. |
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Harnessing immunity for cancer marker discovery pp37 - 38
Sam Hanash
doi:10.1038/nbt0103-37
Abstract | Full text | PDF
(104K)
See also: Research by Mintz et al. |
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| In Brief |
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In Brief p39
doi:10.1038/nbt0103-39
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(204K)
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| Research | Top |
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| Articles |
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Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots pp41 - 46
Xingyong Wu, Hongjian Liu, Jianquan Liu, Kari N. Haley, Joseph A. Treadway, J Peter Larson, Nianfeng Ge, Frank Peale
& Marcel P. Bruchez
Published online: 02 December 2002 | doi:10.1038/nbt764
Abstract | Full text | PDF
(1,997K)
See also: Research News by Jovin |
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Long-term multiple color imaging of live cells using quantum dot bioconjugates pp47 - 51
Jyoti K. Jaiswal, Hedi Mattoussi, J. Matthew Mauro
& Sanford M. Simon
Published online: 02 December 2002 | doi:10.1038/nbt767
Abstract | Full text | PDF
(668K)
See also: Research News by Jovin |
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Transgenic silkworms produce recombinant human type III procollagen in cocoons pp52 - 56
Masahiro Tomita, Hiroto Munetsuna, Tsutomu Sato, Takahiro Adachi, Rika Hino, Masahiro Hayashi, Katsuhiko Shimizu, Namiko Nakamura, Toshiki Tamura
& Katsutoshi Yoshizato
Published online: 16 December 2002 | doi:10.1038/nbt771
Abstract | Full text | PDF
(2,762K)
See also: Research News by Wurm |
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Fingerprinting the circulating repertoire of antibodies from cancer patients pp57 - 63
Paul J. Mintz, Jeri Kim, Kim-Anh Do, Xuemei Wang, Ralph G. Zinner, Massimo Cristofanilli, Marco A. Arap, Waun Ki Hong, Patricia Troncoso, Christopher J. Logothetis, Renata Pasqualini
& Wadih Arap
Published online: 23 December 2002 | doi:10.1038/nbt774
Abstract | Full text | PDF
(1,964K)
See also: Research News by Hanash |
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A transgene-based, embryo-specific lethality system for insect pest management pp64 - 70
Carsten Horn
& Ernst A. Wimmer
Published online: 16 December 2002 | doi:10.1038/nbt769
Abstract | Full text | PDF
(1,064K)
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Rational design of a CD4 mimic that inhibits HIV-1 entry and exposes cryptic neutralization epitopes pp71 - 76
Loïc Martin, François Stricher, Dorothée Missé, Francesca Sironi, Martine Pugnière, Philippe Barthe, Rafael Prado-Gotor, Isabelle Freulon, Xavier Magne, Christian Roumestand, André Ménez, Paolo Lusso, Francisco Veas
& Claudio Vita
Published online: 16 December 2002 | doi:10.1038/nbt768
Abstract | Full text | PDF
(1,494K)
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Immunomodulation of enzyme function in plants by single-domain antibody fragments pp77 - 80
Stephen A. Jobling, Carl Jarman, Min-Min Teh, Niklas Holmberg, Caroline Blake
& Martine E. Verhoeyen
Published online: 16 December 2002 | doi:10.1038/nbt772
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(820K)
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Overexpression of a plasma membrane Na+/H+ antiporter gene improves salt tolerance in Arabidopsis thaliana pp81 - 85
Huazhong Shi, Byeong-ha Lee, Shaw-Jye Wu
& Jian-Kang Zhu
Published online: 09 December 2002 | doi:10.1038/nbt766
Abstract | Full text | PDF
(1,708K)
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| Technical Reports |
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A general method for the covalent labeling of fusion proteins with small molecules in vivo pp86 - 89
Antje Keppler, Susanne Gendreizig, Thomas Gronemeyer, Horst Pick, Horst Vogel
& Kai Johnsson
Published online: 09 December 2002 | doi:10.1038/nbt765
Abstract | Full text | PDF
(1,128K)
| Supplementary Information |
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An efficient protein complex purification method for functional proteomics in higher eukaryotes pp89 - 92
Daniel Forler, Thomas Köcher, Michaela Rode, Mark Gentzel, Elisa Izaurralde
& Matthias Wilm
Published online: 16 December 2002 | doi:10.1038/nbt773
Abstract | Full text | PDF
(1,351K)
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Screening for gene function in chicken embryo using RNAi and electroporation pp93 - 96
Vladimir Pekarik, Dimitris Bourikas, Nicola Miglino, Pascal Joset, Stephan Preiswerk
& Esther T. Stoeckli
Published online: 23 December 2002 | doi:10.1038/nbt770
Abstract | Full text | PDF
(1,991K)
| Supplementary Information |
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| Resources | Top |
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| Patents |
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Enzo Biochem v. Gen-Probe: Complying with the written description requirement under US patent law pp97 - 99
Sasha Blaug, Michael Shuster
& Henry Su
doi:10.1038/nbt0103-97
Abstract | Full text | PDF
(71K)
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Recent patents in nucleic acid synthesis and sequencing p100
doi:10.1038/nbt0103-100
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(30K)
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| People |
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People p101
doi:10.1038/nbt0103-101
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(217K)
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| New on the Market |
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Lab automation and Synthesis & sequencing pp103 - 105
doi:10.1038/nbt0103-103
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(388K)
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| Quiz |
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The Nature Biotechnology 2003 New Year Quiz pp106 - 107
Joe Alper, Aaron Bouchie, Andrew Marshall
& Meeghan Sinclair
doi:10.1038/nbt0103-106
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(72K)
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| Naturejobs | Top |
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| Careers and Recruitment |
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Managing your compensation expectations in today's environment pp109 - 110
John Radford
doi:10.1038/nbt0103-109
Abstract | Full text | PDF
(51K)
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