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A representation of human immunoglobulin G (center), which has now been produced in transchromosomic calves (see p. 889). FISH images in the background indicate the artificial chromosome (red). Photo courtesy Photo Researchers. FISH images courtesy Robl et al.
The combination of a strong science base, and encouraging and supportive private and public sectors, has recently warmed Australia's biotech sector back to life.
Cloned cattle engineered to carry an artificial chromosome encoding human immunoglobulin genes are a significant leap toward the production of safer and more potent therapeutic antibodies.
Growing human embryonic stem cells in an environment free of mouse feeder cells lowers the risk of cross-species infection but does little to clarify what makes stem cells “tick.”
By the imprinting of a molecular memory in their core, dendrimers can be tailored to bind to defined molecular targets in a selective and reversible fashion.